Clinical Trials

Development and Validation of a Natural Language Processing Tool to Generate the CONSORT Reporting Checklist for Randomized Clinical Trials.

IMPORTANCE: Adherence to the Consolidated Standards of Reporting Trials (CONSORT) for randomized clinical trials is associated with improvingquality because inadequate reporting in randomized clinical trials may complicate the interpretation and the application of findings to clinical care.

Cyclic transitions between higher order motifs underlie sustained asynchronous spiking in sparse recurrent networks.

A basic-yet nontrivial-function which neocortical circuitry must satisfy is the ability to maintain stable spiking activity over time. Stable neocortical activity is asynchronous, critical, and low rate, and these features of spiking dynamics contribute to efficient computation and optimal information propagation. However, it remains unclear how neocortex maintains this asynchronous spiking regime...

Effects on sleep from group activity with a robotic seal for nursing home residents with dementia: a cluster randomized controlled trial.

OBJECTIVES: Sleep disturbances are common in people with dementia and increase with the severity of the disease. Sleep disturbances are complex and ca...

The effect of a social robot intervention on sleep and motor activity of people living with dementia and chronic pain: A pilot randomized controlled trial.

OBJECTIVE: To investigate the effect of a social robot intervention on sleep and motor activity in nursing home residents living with dementia and chr...

A comparison of the efficacy, safety, and duration of frame-based and Remebot robot-assisted frameless stereotactic biopsy.

OBJECTIVE: The aim of this study was to compare the efficacy, safety, and duration of Remebot robot-assisted frameless brain biopsy with those of stan...

Evaluation of the enhanced upper limb therapy programme within the Robot-Assisted Training for the Upper Limb after Stroke trial: descriptive analysis of intervention fidelity, goal selection and goal achievement.

OBJECTIVE: To report the fidelity of the enhanced upper limb therapy programme within the Robot-Assisted Training for the Upper Limb after stroke (RAT...

Quality of Care Perceived by Older Patients and Caregivers in Integrated Care Pathways With Interviewing Assistance From a Social Robot: Noninferiority Randomized Controlled Trial.

BACKGROUND: Society is facing a global shortage of 17 million health care workers, along with increasing health care demands from a growing number of ...

Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension.

The CONSORT 2010 statement provides minimum guidelines for reporting randomized trials. Its widespread use has been instrumental in ensuring transpare...

Democratizing AI: non-expert design of prediction tasks.

Non-experts have long made important contributions to machine learning (ML) by contributing training data, and recent work has shown that non-experts ...

Review on big data applications in safety research of intelligent transportation systems and connected/automated vehicles.

The era of Big Data has arrived. Recently, under the environment of intelligent transportation systems (ITS) and connected/automated vehicles (CAV), B...

Ontological approach to the knowledge systematization of a toxic process and toxic course representation framework for early drug risk management.

Various types of drug toxicity can halt the development of a drug. Because drugs are xenobiotics, they inherently have the potential to cause injury. ...

The EEG Signal Analysis for Spatial Cognitive Ability Evaluation Based on Multivariate Permutation Conditional Mutual Information-Multi-Spectral Image.

This study aims to find an effective method to evaluate the efficacy of cognitive training of spatial memory under a virtual reality environment, by c...

Neurocognitive robot-assisted rehabilitation of hand function: a randomized control trial on motor recovery in subacute stroke.

BACKGROUND: Hand function is often impaired after stroke, strongly affecting the ability to perform daily activities. Upper limb robotic devices have ...

A Comparison of the Effect of Fractionated and Bolus Dose Injection on Spinal Anesthesia for Lower Limb Surgery: A Randomized Clinical Trial.

BACKGROUND: In previous clinical trials and a small number of studies, the fractional injection of anesthetics led to reduced physiological complicati...

Complementary Deep and Shallow Learning with Boosting for Public Transportation Safety.

To monitor road safety, billions of records can be generated by Controller Area Network bus each day on public transportation. Automation to determine...

Development and Cross-Validation of a Nomogram for Chronic Kidney Disease Following Robot-Assisted Radical Cystectomy.

We sought to identify the factors associated with deterioration of renal functions after robot-assisted radical cystectomy, and to develop a nomogram...

Effects of two different robot-assisted arm training on upper limb motor function and kinematics in chronic stroke survivors: A randomized controlled trial.

BACKGROUND: Comparative studies of different robotic types are warranted to tailor robot-assisted upper limb training to patient's functional level.

Caregiver burden in stroke inpatients: a randomized study comparing robot-assisted gait training and conventional therapy.

The effects of caregiver burden during the inpatient rehabilitation period have not yet been investigated. The purpose of this study was to evaluate t...

Efficacy of intralesional sodium thiosulfate for the treatment of dystrophic calcinosis cutis: A double-blind, placebo-controlled pilot study.

BACKGROUND: Intralesional injection of sodium thiosulfate has emerged as a promising therapy for calcinosis cutis, but to our knowledge there are no r...

Effects of Exoskeletal Lower Limb Robot Training on the Activities of Daily Living in Stroke Patients: Retrospective Pre-Post Comparison Using Propensity Score Matched Analysis.

PURPOSE: There is limited evidence of gait training using newly developed exoskeletal lower limb robot called Hybrid Assistive Limb (HAL) on the funct...