Clinical Trials

Growth Factor Delivery for the Repair of a Critical Size Tibia Defect Using an Acellular, Biodegradable Polyethylene Glycol-Albumin Hydrogel Implant.

Growth factor delivery using acellular matrices presents a promising alternative to current treatment options for bone repair in critical-size injuries. However, supra-physiological doses of the factors can introduce safety concerns that must be alleviated, mainly by sustaining delivery of smaller doses using the matrix as a depot. We developed an acellular, biodegradable hydrogel implant composed...

Safety and efficacy of transoral robotic and endoscopic thyroidectomy: The first 100 cases.

BACKGROUND: The aim of this study was to evaluate the safety and efficacy of transoral robotic and endoscopic thyroidectomy.

A Wrapper Feature Subset Selection Method Based on Randomized Search and Multilayer Structure.

The identification of discriminative features from information-rich data with the goal of clinical diagnosis is crucial in the field of biomedical sci...

Development of a Deep Learning Model for Dynamic Forecasting of Blood Glucose Level for Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Controlled Trial.

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a major public health burden. Self-management of diabetes including maintaining a healthy lifestyle is ...

Machine learning techniques to predict the effectiveness of music therapy: A randomized controlled trial.

BACKGROUND: The literature shows the effectiveness of music listening, but which factors and what types of music produce therapeutic effects, as well ...

ECG AI-Guided Screening for Low Ejection Fraction (EAGLE): Rationale and design of a pragmatic cluster randomized trial.

BACKGROUND: A deep learning algorithm to detect low ejection fraction (EF) using routine 12-lead electrocardiogram (ECG) has recently been developed a...

Label-Free Estimation of Therapeutic Efficacy on 3D Cancer Spheres Using Convolutional Neural Network Image Analysis.

Despite recent advances in cancer treatment, developing better therapeutic reagents remains an essential task for oncologists. To accurately character...

Training for Walking Efficiency With a Wearable Hip-Assist Robot in Patients With Stroke: A Pilot Randomized Controlled Trial.

Background and Purpose- The purpose of this study was to investigate the effects of gait training with a newly developed wearable hip-assist robot on ...

Efficacy and Safety Evaluation of Human Growth Hormone Therapy in Patients with Idiopathic Short Stature in Korea - A Randomised Controlled Trial.

BACKGROUND: This trial evaluated the efficacy and safety of growth hormone (GH) therapy (Norditropin®; Novo Nordisk, Bagsværd, Denmark) in paediatric ...

Large-Truck Safety Warning System Based on Lightweight SSD Model.

Transportation is an important link in the mining process, and large trucks are one of the important tools for mine transportation. Due to their large...

The use of a machine-learning algorithm that predicts hypotension during surgery in combination with personalized treatment guidance: study protocol for a randomized clinical trial.

BACKGROUND: Intraoperative hypotension is associated with increased morbidity and mortality. Current treatment is mostly reactive. The Hypotension Pre...

Re: Comparing Off-Clamp and On-Clamp Robot-Assisted Partial Nephrectomy: A Prospective Randomized Trial.

Application of Artificial Intelligence in the Health Care Safety Context: Opportunities and Challenges.

There is a growing awareness that artificial intelligence (AI) has been used in the analysis of complicated and big data to provide outputs without hu...

The Effect of Robot Attentional Behaviors on User Perceptions and Behaviors in a Simulated Health Care Interaction: Randomized Controlled Trial.

BACKGROUND: For robots to be effectively used in health applications, they need to display appropriate social behaviors. A fundamental requirement in ...

Formalizing video documentation of the Critical View of Safety in laparoscopic cholecystectomy: a step towards artificial intelligence assistance to improve surgical safety.

BACKGROUND: In laparoscopic cholecystectomy (LC), achievement of the Critical View of Safety (CVS) is commonly advocated to prevent bile duct injuries...

Efficacy and safety of degarelix in patients with prostate cancer: Results from a phase III study in China.

OBJECTIVE: To establish non-inferiority of gonadotropin-releasing hormone degarelix compared with goserelin in suppressing and maintaining castrate te...

[E-health and "Cancer outside the hospital walls", Big Data and artificial intelligence].

To heal otherwise in oncology has become an imperative of Public Health and an economic imperative in France. Patients can therefore receive live most...

Comparing blind spots of unsedated ultrafine, sedated, and unsedated conventional gastroscopy with and without artificial intelligence: a prospective, single-blind, 3-parallel-group, randomized, single-center trial.

BACKGROUND AND AIMS: EGD is the most vital procedure for the diagnosis of upper GI lesions. We aimed to compare the performance of unsedated ultrathin...

Evaluation of essential oils and a prebiotic for newborn dairy calves.

A blend of essential oils (EO) and a prebiotic were combined (EOC) to formulate a colostrum-based liquid birth supplement and a separate feeding suppl...

Interventions to Improve Blood Pressure Control Among Socioeconomically Disadvantaged Patients With CKD: Kidney Awareness Registry and Education Pilot Randomized Controlled Trial.

RATIONALE & OBJECTIVE: Sustainable interventions that enhance chronic kidney disease (CKD) management are not often studied in safety-net primary care...