Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Impact of LLM Assistance on Physician Decision-Making: A Multi-Country Randomized Controlled Trial∗

Disparities in the quality of healthcare persist globally, with poor-quality care contributing signi...

Using transportability methods to map the local effectiveness of mass drug administration for malaria in Senegal

Numerous trials have evaluated the effectiveness of mass drug administration (MDA) to rapidly reduce...

Early Subtypes and Progressions of Progressive Supranuclear Palsy: A Data-Driven Brain Bank Study

Progressive supranuclear palsy (PSP) is typically characterized by vertical supranuclear gaze palsy ...

Epigenetic patient stratification reveals a sub-endotype of type 2 asthma with altered B-cell response

Despite biomarker-guided treatment strategies, clinical outcomes among patients with type 2 (T2)-hig...

Protocol for update of food-based dietary guidelines for Czechia

Current Czech national food-based dietary guidelines are outdated and do not reflect the most recent...

Machine Learning Assisted Differentiation of Low Acuity Patients at Dispatch (MADLAD): A Randomized Controlled Trial

Resource Constrained Situations (RCS) at Emergency Medical Dispatch centers where there are more pat...

Independent contributions of language activations in left and right temporal cortex to aphasia outcomes after stroke

Recovery from aphasia after stroke is thought to depend on functional reorganization of language pro...

Personalized AI Prompt Generator and ChatGPT for Weight Loss: Randomized Controlled Trial in Adults with Overweight and Obesity

The global prevalence of overweight and obesity continues escalating, driven by environmental factor...

Automation Bias in Large Language Model Assisted Diagnostic Reasoning Among AI-Trained Physicians

Large language models (LLMs) show promise for improving clinical reasoning, but they also risk induc...

Candidate Correlates of Protection in the HVTN505 HIV-1 Vaccine Efficacy Trial Identified by Positive-Unlabeled Learning

With a goal of unveiling mechanisms by which vaccines can provide protection against HIV-1 acquisiti...

Factors influencing the trustworthiness of non-randomized studies of interventions: a survey of international experts

Perceived trustworthiness of research may be influenced by factors beyond the risk of bias, includin...

Privacy-Enhancing Sequential Learning under Heterogeneous Selection Bias in Multi-Site EHR Data

To develop privacy-enhancing statistical methods for estimation of binary disease risk model associa...

A randomized clinical trial reveals effects of mindfulness and slow breathing on plasma amyloid beta levels

Prior research suggests that meditation may slow brain aging and reduce the risk of Alzheimer’s dise...

Neurocomputational evidence of sustained Self-Other mergence after psychedelics

Mental illness is often characterised by a maladaptive sense of self. The neurobiological basis of S...

Benchmarking Large Language Models and Clinicians Using Locally Generated Primary Healthcare Vignettes in Kenya

Large language models (LLMs) show promise on healthcare tasks, yet most evaluations emphasize multip...

Music-Induced Cortical Plasticity: Protocol for a Systematic Review

Music engages sensory, motor, cognitive, and emotional systems, making it a powerful model for study...

Improving Surrogate Endpoints for Survival Prediction Through Integration of Patient-Reported Outcomes

Overall survival (OS) remains the gold standard for oncology drug approval, but measuring it require...

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