Clinical Trials

Comparative Evaluation of the Antibacterial Efficacy of Aloe Vera, 3% Sodium Hypochlorite, and 2% Chlorhexidine Gluconate Against Enterococcus faecalis: An In Vitro Study.

Aim To compare the antibacterial efficacy of irrigants (aloe vera, 3% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), and saline) against Enterococcus faecalis using the turbidometric analysis and colony count method. Materials and methods Eighty freshly extracted, single-rooted, human mandibular premolar teeth were taken. Access opening was done, instrumented, and autoclaved. Samples were in...

Comparisons of Pressure-controlled Ventilation with Volume Guarantee and Volume-controlled 1:1 Equal Ratio Ventilation on Oxygenation and Respiratory Mechanics during Robot-assisted Laparoscopic Radical Prostatectomy: a Randomized-controlled Trial.

During robot-assisted laparoscopic radical prostatectomy (RALP), steep Trendelenburg position and carbon dioxide pneumoperitoneum are inevitable for surgical exposure, both of which can impair cardiopulmonary function. This study was aimed to compare the effects of pressure-controlled ventilation with volume guarantee (PCV with VG) and 1:1 equal ratio ventilation (ERV) on oxygenation, respiratory...

Assessment of specific versus combined purpose knowledge based models in prostate radiotherapy.

Knowledge-based planning (KBP) can be used to improve plan quality, planning speed, and reduce the inter-patient plan variability. KPB may also identi...

Effects of robot-(Morning Walk) assisted gait training for patients after stroke: a randomized controlled trial.

OBJECTIVE:: To investigate the effects of Morning Walk-assisted gait training for patients with stroke.

The digital scribe.

Current generation electronic health records suffer a number of problems that make them inefficient and associated with poor clinical satisfaction. Di...

Predicting Adherence to Internet-Delivered Psychotherapy for Symptoms of Depression and Anxiety After Myocardial Infarction: Machine Learning Insights From the U-CARE Heart Randomized Controlled Trial.

BACKGROUND: Low adherence to recommended treatments is a multifactorial problem for patients in rehabilitation after myocardial infarction (MI). In a ...

Application of electronic trigger tools to identify targets for improving diagnostic safety.

Progress in reducing diagnostic errors remains slow partly due to poorly defined methods to identify errors, high-risk situations, and adverse events....

Identify and monitor clinical variation using machine intelligence: a pilot in colorectal surgery.

Standardized clinical pathways are useful tool to reduce variation in clinical management and may improve quality of care. However the evidence suppor...

Clinical efficacy of upper limb robotic therapy in people with tetraplegia: a pilot randomized controlled trial.

STUDY DESIGN: A pilot randomized controlled trial.

Identifying health information technology related safety event reports from patient safety event report databases.

OBJECTIVE: The objective of this paper was to identify health information technology (HIT) related events from patient safety event (PSE) report free-...

Using predicate and provenance information from a knowledge graph for drug efficacy screening.

BACKGROUND: Biomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They re...

Robot-assisted gait training to reduce pusher behavior: A randomized controlled trial.

OBJECTIVE: To determine the effects of 2 weeks of intensive robot-assisted gait training (RAGT) on pusher behavior compared to nonrobotic physiotherap...

Robot-guided pediatric stereoelectroencephalography: single-institution experience.

OBJECTIVEStereoelectroencephalography (SEEG) has increased in popularity for localization of epileptogenic zones in drug-resistant epilepsy because sa...

Automated deep-neural-network surveillance of cranial images for acute neurologic events.

Rapid diagnosis and treatment of acute neurological illnesses such as stroke, hemorrhage, and hydrocephalus are critical to achieving positive outcome...

The Benefit of Fentanyl in Effective Sedation and Quality of Upper Endoscopy: A Double-Blinded Randomized Trial of Fentanyl Added to Midazolam Versus Midazolam Alone for Sedation.

AIMS: Our goals were to compare the effect of adding fentanyl to midazolam in a double-blinded, randomized, placebo-controlled trial and determine if ...

Synbiotic meal decreases uremic toxins in hemodialysis individuals: A placebo-controlled trial.

Generation of uremic toxins p-cresylsulfate (p-CS), indoxyl sulfate (IS) and indole 3-acetic acid (IAA) in hemodialysis (HD) individuals may be associ...

Evaluating the influence of road lighting on traffic safety at accesses using an artificial neural network.

OBJECTIVES: This article focuses on the effect of road lighting on road safety at accesses to quantitatively analyze the relationship between road lig...

Mining heterogeneous networks with topological features constructed from patient-contributed content for pharmacovigilance.

Drug safety, also called pharmacovigilance, represents a serious health problem all over the world. Adverse drug reactions (ADRs) and drug-drug intera...

Big data and machine learning in critical care: Opportunities for collaborative research.

The introduction of clinical information systems (CIS) in Intensive Care Units (ICUs) offers the possibility of storing a huge amount of machine-ready...

Self-Efficacy, Poststroke Depression, and Rehabilitation Outcomes: Is There a Correlation?

BACKGROUND: The sudden live changes of stroke survivors may lead to negative psychological and behavioral outcomes, including anxiety and depressive m...