Clinical Trials

Robot-supported upper limb training in a virtual learning environment : a pilot randomized controlled trial in persons with MS.

BACKGROUND: Despite the functional impact of upper limb dysfunction in multiple sclerosis (MS), effects of intensive exercise programs and specifically robot-supported training have been rarely investigated in persons with advanced MS.

Efficacy of Postoperative Pain Management Using Continuous Local Anesthetic Infusion at the Iliac Crest Bone Graft Site in Patients with Adolescent Idiopathic Scoliosis: A Parallel, Double-Blinded, Randomized Controlled Pilot Trial.

Study Design Randomized controlled trial. Objective Adolescent idiopathic scoliosis (AIS) is a common spinal deformity that affects every population. In severe deformity, surgical intervention is performed. Autogenous iliac crest bone graft (ICBG) harvesting remains a common procedure worldwide for scoliosis surgery. Postoperative pain at the ICBG donor site is a major concern in patients undergoi...

Lidocaine 5% Patch for Treatment of Acute Pain After Robotic Cardiac Surgery and Prevention of Persistent Incisional Pain: A Randomized, Placebo-Controlled, Double-Blind Trial.

OBJECTIVES: To test the hypotheses that lidocaine 5% patches decrease the severity of acute pain and incidence of persistent incisional pain after rob...

Towards a Food Safety Knowledge Base Applicable in Crisis Situations and Beyond.

In case of contamination in the food chain, fast action is required in order to reduce the numbers of affected people. In such situations, being able ...

Global harmonization of safety regulations for the use of industrial robots-permission of collaborative operation and a related study by JNIOSH.

In December 2013, the Japanese Ministry of Health, Labour and Welfare (MHLW) partially amended the safety regulations for use of industrial robots so ...

Controlling Listeria monocytogenes Scott A on Surfaces of Fully Cooked Turkey Deli Product Using Organic Acid-Containing Marinades as Postlethality Dips.

This study evaluated the efficacy of organic acids applied singly or in combination as postlethality dips to sliced uncured turkey deli loaves to inhi...

Effects on Symptoms of Agitation and Depression in Persons With Dementia Participating in Robot-Assisted Activity: A Cluster-Randomized Controlled Trial.

OBJECTIVES: To examine effects on symptoms of agitation and depression in nursing home residents with moderate to severe dementia participating in a r...

Population pharmacokinetic/pharmacodynamic assessment of pharmacological effect of a selective estrogen receptor β agonist on total testosterone in healthy men.

BACKGROUND: LY500307 is a highly selective estrogen receptor β (ERβ) agonist, which loses its selectivity at high dose and leads to undesirable suppre...

Understanding safety-critical interactions with a home medical device through Distributed Cognition.

As healthcare shifts from the hospital to the home, it is becoming increasingly important to understand how patients interact with home medical device...

What device should be used for telementoring? Randomized controlled trial.

BACKGROUND AND OBJECTIVE: The paper analyzes behavioral patterns of mentors while using different mentoring devices to demonstrate the feasibility of ...

Comparison of Coopdech®, CoPilot®, Intubrite®, and Macintosh laryngoscopes for tracheal intubation during pediatric cardiopulmonary resuscitation: a randomized, controlled crossover simulation trial.

UNLABELLED: The aim of the study was to compare the intubation times and success rates of various laryngoscopes during resuscitation in pediatric emer...

A review on the mechanical design elements of ankle rehabilitation robot.

Ankle rehabilitation robots are developed to enhance ankle strength, flexibility and proprioception after injury and to promote motor learning and ank...

Driver's behavioural changes with new intelligent transport system interventions at railway level crossings--A driving simulator study.

Improving safety at railway level crossings is an important issue for the Australian transport system. Governments, the rail industry and road organis...

Gait training in subacute non-ambulatory stroke patients using a full weight-bearing gait-assistance robot: A prospective, randomized, open, blinded-endpoint trial.

BACKGROUND: This study was a prospective, randomized, open, blinded-endpoint trial with the aim of examining whether gait training with a gait-assista...

Efficacy of robot-assisted fingers training in chronic stroke survivors: a pilot randomized-controlled trial.

BACKGROUND: While constraint-induced movement therapy (CIMT) is one of the most promising techniques for upper limb rehabilitation after stroke, it re...

Effects of Innovative WALKBOT Robotic-Assisted Locomotor Training on Balance and Gait Recovery in Hemiparetic Stroke: A Prospective, Randomized, Experimenter Blinded Case Control Study With a Four-Week Follow-Up.

The present clinical investigation was to ascertain whether the effects of WALKBOT-assisted locomotor training (WLT) on balance, gait, and motor recov...

An Evaluation of Patient Safety Event Report Categories Using Unsupervised Topic Modeling.

OBJECTIVE: Patient safety event data repositories have the potential to dramatically improve safety if analyzed and leveraged appropriately. These saf...

Comparing the efficacy and safety between robotic-assisted versus open pyeloplasty in children: a systemic review and meta-analysis.

OBJECTIVE: This manuscript is mainly to systemically review the published reports that compared the efficacy and safety of robotic-assisted (RP) versu...

Robotic-assisted gait training in neurological patients: who may benefit?

Regaining one's ability to walk is of great importance for neurological patients and is a major goal of all rehabilitation programs. Gait training of ...

Urodynamic Efficacy and Safety of Mirabegron Add-on Treatment with Tamsulosin for Japanese Male Patients with Overactive Bladder.

OBJECTIVES: To investigate urodynamic efficacy and safety of mirabegron add-on treatment with tamsulosin for Japanese male patients with overactive bl...