Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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An interpretable 1⁸F-PSMA PET/CT-MRI model for optimizing prostate biopsy decisions.

PURPOSE: Distinguishing indolent from clinically significant prostate cancer (csPCa) in biopsy-naïve men remains a diagnostic challenge, often leading to unnecessary biopsies. This study aimed to develop and externally validate an interpretable multimodal model integrating 18F-PSMA PET/CT, mpMRI, and clinical variables to predict csPCa and optimize biopsy decision-making. METHODS: This multicenter...

May 23 2026 42176196

Clin-STAR Corner: Practice Changing Advances at the Interface of Artificial Intelligence/Machine Learning and Geriatrics.

Artificial intelligence (AI) methods, including machine learning (ML), are transforming healthcare by enabling personalized interventions that integrate multimodal data to support rehabilitation, preventive care, and remote monitoring. Despite their broad potential, older adults remain underrepresented in model development, raising concerns about bias and limited generalizability. As AI/ML adoptio...

May 23 2026 42176238
Affective processes in perceived inclusive EFL classrooms: Linking self-efficacy, engagement, resilience, and attitudes toward generative AI.

Inclusive education, extending beyond classroom access to emphasize affective support, equitable participation, and learner diversity, frames this stu...

May 23 2026 42176447
Effectiveness of a generative AI-powered digital tutor integrated with a knowledge graph in anatomy education for nursing students: a randomized controlled trial.

BACKGROUND: Human Anatomy and Histology & Embryology are foundational courses in nursing education but are often challenging for students due to their...

May 22 2026 42174555
Application of AI-assisted PBL-CBL combined teaching in the diagnosis and treatment of post-herpetic neuralgia: a randomised controlled trial.

BACKGROUND: This study aimed to explore the efficacy of a teaching model integrating artificial intelligence-assisted problem-based learning (PBL) wit...

May 22 2026 42174592
Virtual crystal violet chromoendoscopy: a digital alternative to dye-based staining.

BACKGROUND AND AIMS: Routine use of crystal violet (CV) chromoendoscopy for pit pattern-based colorectal lesion characterization is limited by safety ...

May 22 2026 42176744
A machine learning-derived speech index as a biomarker for Huntington's disease severity.

BACKGROUND: The development of disease-modifying therapies for Huntington's disease (HD) necessitates sensitive, scalable, and objective biomarkers fo...

May 22 2026 42171798
Twelve Tips for Recognizing and Addressing the Adverse Effects of Medical Education Interventions: Tutorial.

"First, do no harm" is a fundamental principle in health care, and clinical researchers carefully monitor adverse drug reactions to ensure patient saf...

May 22 2026 42172571
Beyond the digital health tsunami: reaffirming biomedical and health informatics as the scientific foundation of digital healthcare transformation.

Digital health (DH) has emerged as the dominant terminology for technology-enabled healthcare, reshaping institutional discourse, educational programm...

May 22 2026 42173551
LSTM-based safety-oriented prediction of big toe skin temperature in extreme cold conditions for mountaineering footwear evaluation.

This study proposes a safety-oriented framework for the assessment of mountaineering footwear insulation in extreme cold environments. A novel metric,...

May 22 2026 42173984
Machine learning based hepatic safety score predicts decompensation in hepatocellular carcinoma systemic therapy.

Hepatocellular carcinoma (HCC) frequently coexists with portal hypertension, significantly increasing the risk of hepatic decompensation (HD) and vari...

May 22 2026 42168526
Using Machine Learning Methodology to Identify Predictors of Non-Response to MTSS-B: a Focus on Discipline Problems and Juvenile Justice Involvement.

Multi-tiered systems of support for behavior (MTSS-B) is a widely-used tiered preventive intervention currently used in over 25,000 schools across the...

May 22 2026 42168693
Effectiveness of tele-rehabilitation using AI-guided exercise and pain neuroscience education for fibromyalgia (FIBROIA): Protocol for a randomized controlled trial.

INTRODUCTION: Fibromyalgia (FM) is a chronic condition characterized by widespread pain and cognitive dysfunction, with pharmacological treatments off...

May 22 2026 42172217
A Comparison of Different Models to Recommend Variables for Research Data Requests to German Cancer Registries.

Cancer registry data is an important resource in cancer research, e.g. to formulate hypotheses for new interventions, to identify recruitment potentia...

May 21 2026 42174835
Bridging Expertise with Algorithms: Evaluation of Generative AI in Nursing Decisions.

Integrating generative artificial intelligence (GenAI) into nursing clinical decision-making (CDM) offers potential to bridge expertise gaps. This ran...

May 21 2026 42174837
Advancing Knowledge in Evaluating the Clinical Impact of Large Language Models for Clinical Text Summarization: A Narrative Review.

Large language models (LLMs) are increasingly explored for clinical text summarization from electronic health records (EHRs), where they could reduce ...

May 21 2026 42174918
Aligning AI-Native 6G Healthcare Systems with EU Ethical and Legal Frameworks.

The convergence of AI, robotics, and 6G networks is reshaping healthcare through real-time This paper applies a structured regulatory-technical analys...

May 21 2026 42174947
Crique: A System for Automatic Extraction and Formalization of Eligibility Criteria for Clinical Trials.

Defining formal and structured eligibility criteria for digital recruitment assistant systems can be a challenging interdisciplinary task requiring co...

May 21 2026 42174964
Assessing Clinical Decision-Making Aided by a RAG-Based Dialog in Pre-Examination on Non-Odontogenic Tooth Pain.

Differentiating Non-Odontogenic Tooth Pain, a potential symptom of life-threatening conditions like Ischemic Heart Disease, is a critical challenge fo...

May 21 2026 42175018
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