Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Generative AI Chatbots as Digital Adjuncts for Sexual Health Information After Prostate Cancer in Men Who Have Sex With Men: Auto-Netnographic Study.

BACKGROUND: Sexual health concerns following prostate cancer treatment are common yet often insufficiently addressed in clinical practice, particularly among men who have sex with men. These individuals may face additional barriers stemming from heteronormative assumptions, limited disclosure, and a lack of culturally tailored information. As generative artificial intelligence (GenAI) chatbots bec...

Feb 9 2026 41662502

Effects of Lactiplantibacillus plantarum on moderate dyslipidemia before medication involving gut microbiota and host genetics.

In this 12-week trial, 136 participants with moderately dyslipidemia were randomly assigned to receive Lactiplantibacillus plantarum (LP) or placebo. In the intention-to-treat analysis, the group-by-time interaction did not reach statistical significance. However, in per-protocol set (adherence ≥85% and no antibiotic use), LP supplementation reduced low-density lipoprotein cholesterol (LDL-C) (-0....

Feb 9 2026 41663420
Foundations, evidence, and applications of translational simulation in obstetric anaesthesia: a narrative review.

Obstetric anaesthetists work in high-acuity settings where maternal and fetal conditions can deteriorate rapidly, requiring coordinated action across ...

Feb 8 2026 41663293
TFAP2A transcriptionally regulates B3GALT2 to affect gouty arthritis progression through pyroptosis: a study based on machine learning and multi-omics integration analysis.

BACKGROUND: Gouty arthritis (GA) is an inflammatory joint disease driven by monosodium urate (MSU) crystal deposition. The NOD-like receptor thermal p...

Feb 8 2026 41654938
Predicting the Apnea-Hypopnea index for the diagnosis of obstructive sleep apnea with cardiovascular and cancer comorbidity using wearable sleep-tracking devices.

INTRODUCTION: Obstructive Sleep Apnea (OSA) is a highly prevelance sleep breathing disorder that imposes, significant public health and economic burde...

Feb 7 2026 41653357
From wrinkles to malignancy: small-molecule-mediated stem cell approaches in skin aging.

Skin aging is driven by the progressive exhaustion of stem cell niches, epigenetic drift, and accumulation of senescent cells, which together promote ...

Feb 6 2026 41655728
Empowered by AI: exploring the link between literacy, self-efficacy, and career expectations.

Artificial intelligence is reshaping higher education, yet little is known about how students' AI related beliefs connect to their career expectations...

Feb 6 2026 41653767
Malpractice in the machine age: Legal and ethical responses to machine learning in medical imaging.

OBJECTIVES: Artificial intelligence (AI) and machine learning (ML) are increasingly integrated into diagnostic imaging. This review examines how AI ad...

Feb 6 2026 41653871
Perceived Potential and Challenges of Supporting Coronary Artery Disease Treatment Decisions With AI: Qualitative Study.

BACKGROUND: Coronary revascularization decision-making for patients with coronary artery disease (CAD) can be complex and challenging. Artificial inte...

Feb 6 2026 41650180
AI Scribes: Are We Measuring What Matters?

Artificial intelligence (AI) scribes, software that can convert speech into concise clinical documents, have achieved remarkable clinical adoption at ...

Feb 6 2026 41650281
Combating Antiviral Drug Resistance: A Multipronged Strategy.

ConspectusViral proteases are essential enzymes required for viral replication and assembly, making them prime antiviral drug targets. However, under ...

Feb 6 2026 41650319
Artificial intelligence-powered analysis of operating room turnover: impact of instrument burden.

OBJECTIVE: Improved operating room (OR) efficiency provides greater patient throughput, reduced costs, and maximal patient care. The aim of this study...

Feb 6 2026 41650394
A large language model for complex cardiology care.

The scarcity of subspecialist medical expertise poses a considerable challenge for healthcare delivery. This issue is particularly acute in cardiology...

Feb 6 2026 41652123
Intravitreal faricimab in patients with refractory diabetic macular edema: 6-month fluid analysis using artificial intelligence.

PURPOSE: Diabetic macular edema (DME) is a leading cause of vision loss in patients with diabetes. In developed countries, intravitreal (IVT) anti-vas...

Feb 6 2026 41652390
A graph-based safe reinforcement learning method for multi-agent cooperation.

Safety and Restricted Communication are two critical challenges faced by practical Multi-Agent Systems (MAS). However, most Multi-Agent Reinforcement ...

Feb 5 2026 41719968
Machine learning modeling for predicting growth dynamics of Listeria monocytogenes using ComBase database: A comprehensive feature engineering approach.

Traditional mechanistic models for Listeria monocytogenes prediction face limitations in capturing synergistic environmental interactions and nonlinea...

Feb 5 2026 41794467
A physical information neural network-based path planning method for flexible needle puncture of soft tissues.

BACKGROUND: Flexible needle puncture is a critical minimally invasive technique where path planning accuracy directly impacts clinical outcomes. Tradi...

Feb 5 2026 41645426
The future of PCOS management: Disease modification through regenerative, metabolic, and digital therapeutics.

Polycystic ovary syndrome (PCOS) represents the leading endocrine problem affecting women of reproductive age, leading to serious complications relate...

Feb 5 2026 41666555
A Review Exploring the Translational Perspective of Artificial Intelligence in Drug Discovery and Formulation Development.

The drug development pipeline remains extraordinarily complex, costly, and time-intensive, typically requiring 10-15 years and $2-3 billion per approv...

Feb 5 2026 41653969
Governance Framework for Safe and Ethical Implementation of Artificial Intelligence in Surgery: A Modified-Delphi Consensus.

BACKGROUND: Artificial intelligence (AI)-enabled clinical decision support systems (CDSS) demonstrate performance comparable or superior to human expe...

Feb 5 2026 41641894
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