Clinical Trials

From traditional medicine to modern medicine: the importance of TCM regulatory science (TCMRS) as an emerging discipline.

Traditional Chinese medicine (TCM) has become a standardized medical system through systematic development across global healthcare practices. However, concerns persist regarding the safety, efficacy and quality of traditional medicinal products. Traditional Chinese medicine regulatory science (TCMRS) has emerged as an interdisciplinary field to address these challenges. This discipline integrates...

[Current situation and development trends of minimally invasive surgical procedures in the treatment of pancreatic tumors].

With the rapid development of modern medical technology,minimally invasive surgical procedures are playing an increasingly important role in the field of pancreatic tumor treatment. This article systematically expounds on the application status of minimally invasive surgical procedures,including robotic surgery and laparoscopic surgery,in the treatment of pancreatic tumors. Through in-depth analys...

Evaluating a brief smartphone-based stress management intervention with heart rate biofeedback from built-in sensors in a three arm randomized controlled trial.

Perceived stress is prevalent in industrial societies, negatively impacting mental health. Smartphone-based stress management interventions provide ac...

Intervention through an intelligent technological platform for socio-emotional development and health promotion in adolescents with Type 1 Diabetes Mellitus (emoTICare): A study protocol for randomized controlled trial.

BACKGROUND: During adolescence, individuals face various challenges that require adequate psychosocial and emotional adjustment. Additionally, the pre...

Evaluation of flight crew risk factors in aviation occupational health and safety: Application of Fermatean Fuzzy DEMATEL approach and machine learning.

BackgroundFlight crews operate in an environment surrounded by a wide array of physical, chemical, biological, ergonomic, and psychosocial risks. It i...

Comparison of a novel gamified binocular therapy and standard monocular patching therapy in treating unilateral amblyopia in young children: a prospective, multicenter, randomized controlled trial.

BACKGROUND: Amblyopia is a leading cause of visual impairment in children, and conventional treatments often encounter challenges related to poor comp...

Artificial Intelligence-assisted Endoscopy and Examiner Confidence: A Study on Human-Artificial Intelligence Interaction in Barrett's Esophagus (With Video).

OBJECTIVE: Despite high stand-alone performance, studies demonstrate that artificial intelligence (AI)-supported endoscopic diagnostics often fall sho...

Advances in vaccine adjuvant development and future perspectives.

Use of highly purified antigens to improve vaccine safety has led to reduced immunogenicity and efficacy, resulting in the need for adjuvants to incre...

Empirically derived evaluation requirements for responsible deployments of AI in safety-critical settings.

Processes to assure the safe, effective, and responsible deployment of artificial intelligence (AI) in safety-critical settings are urgently needed. H...

Understanding and acceptance of open, laparoscopic, and robotic surgery among nursing students: implications for educational curricula based on a mixed-methods study.

This study aimed to assess university nursing students' knowledge and perceptions of open, laparoscopic, and robotic surgery applications. A simultane...

Analysis of the neural mechanisms of social anxiety based on EEG features and machine learning and construction of a diagnostic model.

Social anxiety is a common psychological problem, and its accurate diagnosis and investigation of underlying neurophysiological mechanisms are of sign...

Artificial Intelligence in Predicting Efficacy and Toxicity of Immunotherapy: Applications, Challenges, and Future Directions.

Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, becoming a standard approach for various tumor types. Consequently, accurate...

The role of tumor microenvironment and immune cell crosstalk in triple-negative breast cancer (TNBC): Emerging therapeutic opportunities.

Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by its lack of estrogen, progesterone, and HER2 receptors, leading to limi...

Effectiveness of an Artificial Intelligence-Infused SinDance Exergame for Enhancing Physical Functions and Well-Being in Older Adults: A Pilot Randomized Controlled Trial.

The acceptance of ophthalmic artificial intelligence for eye diseases: a literature review and qualitative analysis.

Thorough investigations of end-users' awareness, acceptance, and concerns about ophthalmic artificial intelligence (AI) are essential to ensure its su...

Research on the evaluation and rehabilitation training system of upper limb motor function for poststroke patients based on artificial intelligence: a study protocol for a randomized controlled trial.

BACKGROUND: Stroke-induced upper limb dysfunction requires functional assessment and rehabilitation. The intelligent rehabilitation assessment and vir...

Evaluating Equity in Usage and Effectiveness of the CONCERN Early Warning System.

BACKGROUND: The CONCERN Early Warning System (CONCERN EWS) is an artificial intelligence based clinical decision support system (AI-CDSS) for predicti...

Heart rate variability in patients with cardiovascular diseases.

Heart rate variability (HRV) has been reported to predict overall mortality and the risk of cardiovascular disease events in patients, including those...

Artificial intelligence-assisted diagnosis and prognostication in low ejection fraction using electrocardiograms in inpatient department: a pragmatic randomized controlled trial.

BACKGROUND: Early diagnosis of low ejection fraction (EF) remains challenging despite being a treatable condition. This study aimed to evaluate the ef...

The illusion of safety: A report to the FDA on AI healthcare product approvals.

Artificial intelligence is rapidly transforming healthcare, offering promising advancements in diagnosis, treatment, and patient outcomes. However, co...