Clinical Trials

Experiencing digital technologies: The importance of feeling safe in healthcare - A qualitative participatory design.

Digital technologies are increasingly used in healthcare. In this context, perceived safety plays a critical role in their acceptance and implementation. Previous research had focused more on data security or specific digital technologies. There has also been a lack of participatory approaches to consider and empower healthcare recipients (and relatives), providers, and technology experts to broad...

Exploring the complex nature of implementation of Artificial intelligence in clinical practice: an interview study with healthcare professionals, researchers and Policy and Governance Experts.

Artificial Intelligence (AI)-based tools have shown potential to optimize clinical workflows, enhance patient quality and safety, and facilitate personalized treatment. However, transitioning viable AI solutions to clinical implementation remains limited. To understand the challenges of bringing AI into clinical practice, we explored the experiences of healthcare professionals, researchers, and Po...

Systemic therapy informed self-help and paraprofessional training in a naturalistic setting: study protocol of a digital randomised trial.

BACKGROUND: Multiple studies have shown the efficacy of Systemic Psychotherapy (ST) approaches as a promising path to address various mental health di...

Evaluation of the Efficacy of Step-down Therapy with Oral Minocycline for Complicated Pyelonephritis Caused by Extended-Spectrum β-Lactamase-Producing Enterobacterales: A Retrospective Cohort Study.

BACKGROUND: Extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) infections present significant treatment challenges owing to limited ora...

Anomaly Detection in Electronic Health Records Across Hospital Networks: Integrating Machine Learning With Graph Algorithms.

In a large hospital system, a network of hospitals relies on electronic health records (EHRs) to make informed decisions regarding their patients in v...

A robotic-assisted intervention (ROBERT®) to enhance muscle strength in the hip flexor muscles following spinal cord injury: A pilot within-person randomized controlled trial.

OBJECTIVE: To determine whether a robotic-assisted intervention increases hip flexor muscle strength in people with spinal cord injury (SCI) and marke...

Collision risk prediction and takeover requirements assessment based on radar-video integrated sensors data: A system framework based on LLM.

There are safety risks when drivers take over the control of autonomous driving vehicles, and reducing unnecessary takeovers is essential to improve d...

GLIO-Select: Machine Learning-Based Feature Selection and Weighting of Tissue and Serum Proteomic and Metabolomic Data Uncovers Sex Differences in Glioblastoma.

Glioblastoma (GBM) is a fatal brain cancer known for its rapid and aggressive growth, with some studies indicating that females may have better surviv...

Integrating genetic variation with deep learning provides context for variants impacting transcription factor binding during embryogenesis.

Understanding how genetic variation impacts transcription factor (TF) binding remains a major challenge, limiting our ability to model disease-associa...

Efficacy of eprinomectin 5 mg/mL topical solution administered twice pour on at 1 mg per kg body weight against sarcoptic mange (Sarcoptes scabiei) in sheep.

Sarcoptic mange of sheep is a skin disease which compromises the health and welfare of the animals, impacts their productivity and is zoonotic. In Eur...

Recruiting Teacher IF Modality for Nephropathy Diagnosis: A Customized Distillation Method With Attention-Based Diffusion Network.

The joint use of multiple modalities for medical image processing has been widely studied in recent years. The fusion of information from different mo...

Stricter cadmium and lead standards needed for organic fertilizers in China.

This study aims to evaluate the adequacy of China's national standards for heavy metals in organic fertilizers by predicting their concentrations in g...

Mediating effect of AI attitudes and AI literacy on the relationship between career self-efficacy and job-seeking anxiety.

As artificial intelligence (AI) technology quickly grows, college students have new worries and fears. Using Marx's theory of labour alienation, this ...

Urban walkability through different lenses: A comparative study of GPT-4o and human perceptions.

Urban environments significantly shape our well-being, behavior, and overall quality of life. Assessing urban environments, particularly walkability, ...

Cyclist safety in the digital age: A review of advanced warning technologies.

Improving the safety of cyclists, who are considered vulnerable road users, is essential. Implementing a warning system that alerts cyclists to nearby...

A NLP analysis of digital demand for healthcare jobs in China.

The rapid growth of the healthcare industry in China has led to a significant talent gap, particularly in the areas of digital skills and management e...

Single Joint Hybrid Assistive Limb (HAL-SJ) robotic exoskeleton therapy in improving functional outcomes among workers with wrist fractures: Study protocol for a randomized controlled trial.

INTRODUCTION: Robotic technologies have been developed for motor rehabilitation and such robots have shown favourable results when compared with equiv...

Mechanism Exploration of Dietary Supplement Astaxanthin on Improving Atherosclerosis through an Integrated Strategy Encompassing Artificial Intelligence Virtual Screening and Experimental Validation.

Atherosclerosis (AS) is a major and common pathological basis of ischemic intestinal infarction, myocardial infarction, stroke, renal failure, and oth...

Multicontact Safety-Critical Planning and Adaptive Neural Control of a Soft Exosuit Over Different Terrains.

Many previous works on wearable soft exosuits have primarily focused on assisting human motion, while overlooking safety concerns during movement. Thi...

Emerging artificial intelligence-driven precision therapies in tumor drug resistance: recent advances, opportunities, and challenges.

Drug resistance is one of the main reasons for cancer treatment failure, leading to a rapid recurrence/disease progression of the cancer. Recently, ar...