Clinical Trials

Real-time assistance in suicide prevention helplines using a deep learning-based recommender system: A randomized controlled trial.

OBJECTIVE: To evaluate the effectiveness and usability of an AI-assisted tool in providing real-time assistance to counselors during suicide prevention helpline conversations.

Next-Gen Therapeutics: Pioneering Drug Discovery with iPSCs, Genomics, AI, and Clinical Trials in a Dish.

In the high-stakes arena of drug discovery, the journey from bench to bedside is hindered by a daunting 92% failure rate, primarily due to unpredicted toxicities and inadequate therapeutic efficacy in clinical trials. The FDA Modernization Act 2.0 heralds a transformative approach, advocating for the integration of alternative methods to conventional animal testing, including cell-based assays tha...

ChatGPT as a patient education tool in colorectal cancer-An in-depth assessment of efficacy, quality and readability.

AIM: Artificial intelligence (AI) chatbots such as Chat Generative Pretrained Transformer-4 (ChatGPT-4) have made significant strides in generating hu...

Efficacy of preoperative prophylactic application of betamethasone on postoperative nausea and vomiting in patients undergoing total knee arthroplasty: a prospective randomized controlled trial.

BACKGROUND: The demand for total knee arthroplasty (TKA) is increasing, yet postoperative nausea and vomiting (PONV) significantly hinder patient reco...

Ethical Application of Generative Artificial Intelligence in Medicine.

Generative artificial intelligence (AI) may revolutionize health care, providing solutions that range from enhancing diagnostic accuracy to personaliz...

Analysis of HIV infection among voluntary blood donors based on HIV ELISA and nucleic acid detection.

OBJECTIVE: To analyze the epidemiological characteristics of human immunodeficiency virus (HIV) infection among voluntary blood donors and provide a f...

Predicting student self-efficacy in Muslim societies using machine learning algorithms.

INTRODUCTION: Self-efficacy is a critical determinant of students' academic success and overall life outcomes. Despite its recognized importance, rese...

Antibacterial Activity of Crude , , and Methanolic Extracts on serovar Manilae.

BACKGROUND AND OBJECTIVE: Leptospirosis is a disease caused by pathogenic prevalent in tropical countries like the Philippines. Some studies have sho...

Revolutionizing the construction industry by cutting edge artificial intelligence approaches: a review.

The construction industry is rapidly adopting Industry 4.0 technologies, creating new opportunities to address persistent environmental and operationa...

Model-informed approach to estimate treatment effect in placebo-controlled clinical trials using an artificial intelligence-based propensity weighting methodology to account for non-specific responses to treatment.

In randomized, placebo controlled clinical trials (RCT) in major depressive disorders (MDD), treatment response (TR) is estimated by the change from b...

From Code to Clots: Applying Machine Learning to Clinical Aspects of Venous Thromboembolism Prevention, Diagnosis, and Management.

The high incidence of venous thromboembolism (VTE) globally and the morbidity and mortality burden associated with the disease make it a pressing issu...

Flexibility and resilience in equity-centered research: lessons learned conducting a randomized controlled trial of a family-based substance use prevention program for American Indian families.

Meaningful and effective community engagement lies at the core of equity-centered research, which is a powerful tool for addressing health disparities...

Heparin in sepsis: current clinical findings and possible mechanisms.

Sepsis is a clinical syndrome resulting from the interaction between coagulation, inflammation, immunity and other systems. Coagulation activation is ...

The Effect of Different Bleaching Techniques Using 6% Hydrogen Peroxide: Penetration Inside the Pulp Cavity, Bleaching Efficacy and Toxicity.

This in vitro study aimed to quantify the penetration of hydrogen peroxide (HP), bleaching efficacy (BE) and toxicity in larvae in different bleaching...

Effectiveness of unilateral lower-limb exoskeleton robot on balance and gait recovery and neuroplasticity in patients with subacute stroke: a randomized controlled trial.

BACKGROUND: Impaired balance and gait in stroke survivors are associated with decreased functional independence. This study aimed to evaluate the effe...

A mixed methods crossover randomized controlled trial exploring the experiences, perceptions, and usability of artificial intelligence (ChatGPT) in health sciences education.

BACKGROUND: Generative artificial intelligence (AI) integrated programs such as Chat Generative Pre-trained Transformers (ChatGPT) are becoming more w...

Effects of Robot-Assisted Gait Training on Balance and Fear of Falling in Patients With Stroke: A Randomized Controlled Clinical Trial.

OBJECTIVE: The aim of this study was compare the effects of combined training, which included robot-assisted gait training in addition to traditional ...

Cohort profile: AI-driven national Platform for CCTA for clinicaL and industriaL applicatiOns (APOLLO).

PURPOSE: Coronary CT angiography (CCTA) is well established for the diagnostic evaluation and prognostication of coronary artery disease (CAD). The gr...

Using deep learning and word embeddings for predicting human agreeableness behavior.

The latest advancements of deep learning have resulted in a new era of natural language processing. The machines now possess an unparallel ability to ...

Diagnosis of Pain Deception Using Minnesota Multiphasic Personality Inventory-2 Based on XGBoost Machine Learning Algorithm: A Single-Blinded Randomized Controlled Trial.

: Assessing pain deception is challenging due to its subjective nature. The main goal of this study was to evaluate the diagnostic value of pain decep...