Clinical Trials

Artificial intelligence in health care: accountability and safety.

The prospect of patient harm caused by the decisions made by an artificial intelligence-based clinic...

The Metabolic Rainbow: Deep Learning Phase I Metabolism in Five Colors.

Metabolism of drugs affects their absorption, distribution, efficacy, excretion, and toxicity profil...

A comparison between Artificial Neural Network and Hybrid Intelligent Genetic Algorithm in predicting the severity of fixed object crashes among elderly drivers.

Run-off-road (ROR) crashes have always been a major concern as this type of crash is usually associa...

Identifying treatment effects of an informal caregiver education intervention to increase days in the community and decrease caregiver distress: a machine-learning secondary analysis of subgroup effects in the HI-FIVES randomized clinical trial.

BACKGROUND: Informal caregivers report substantial burden and depressive symptoms which predict high...

Letter to the Editor Re: "The Effects of a Robot-Assisted Arm Training Plus Hand Functional Electrical Stimulation on Recovery After Stroke: A Randomized Clinical Trial".

Robot-assisted radical cystectomy: Review of surgical technique, and perioperative, oncological and functional outcomes.

Since the introduction of robot-assisted radical cystectomy, efforts have been made to meet the stan...

Beyond the Randomized Clinical Trial: Innovative Data Science to Close the Pediatric Evidence Gap.

Despite the application of advanced statistical and pharmacometric approaches to pediatric trial dat...

Image Quality and Lesion Detection on Deep Learning Reconstruction and Iterative Reconstruction of Submillisievert Chest and Abdominal CT.

The objective of this study was to compare image quality and clinically significant lesion detectio...

Fuzzy Logic-Based Risk Assessment of a Parallel Robot for Elbow and Wrist Rehabilitation.

A few decades ago, robotics started to be implemented in the medical field, especially in the rehabi...

Adaptive Ankle Resistance from a Wearable Robotic Device to Improve Muscle Recruitment in Cerebral Palsy.

Individuals with cerebral palsy can have weak and poorly coordinated ankle plantar flexor muscles th...

Predicting real-time traffic conflicts using deep learning.

Recently, technologies for predicting traffic conflicts in real-time have been gaining momentum due ...

Motivational interviewing and culture for urban Native American youth (MICUNAY): A randomized controlled trial.

To date, few programs that integrate traditional practices with evidence-based practices have been d...

Effects of aged garlic extract on arterial elasticity in a placebo-controlled clinical trial using EndoPAT™ technology.

Cardiovascular diseases are the main cause of death in the industrialized world, with the main risk ...

Beyond Performance Metrics: Automatic Deep Learning Retinal OCT Analysis Reproduces Clinical Trial Outcome.

PURPOSE: To validate the efficacy of a fully automatic, deep learning-based segmentation algorithm b...

Estimating individualized treatment regimes from crossover designs.

The field of precision medicine aims to tailor treatment based on patient-specific factors in a repr...

Right Dose Right Now: bedside data-driven personalized antibiotic dosing in severe sepsis and septic shock - rationale and design of a multicenter randomized controlled superiority trial.

BACKGROUND: Antibiotic exposure is often inadequate in critically ill patients with severe sepsis or...

Pharmacokinetic-pharmacodynamic assessment of the ivermectin and abamectin nematodicidal interaction in cattle.

In a context of nematodicidal resistance, anthelmintic combinations have emerged as a reliable pharm...

Out damn bot, out: Recruiting real people into substance use studies on the internet.

While the Internet has become a popular and effective strategy for recruiting substance users into r...

Cell proliferation activity delineated by molecular docking of four new compounds isolated from the aerial parts of Forssk. ex. J.F. Gmel.

Using different chromatographic methods, four new compounds were isolated from the aerial parts of ...

Immunogenicity and safety of a 12-valent pneumococcal conjugate vaccine in infants aged 6-10 weeks: a randomized double-blind active-controlled trial.

BACKGROUND: Pneumococcal diseases among children aged <5 years worldwide are associated with high an...

The influence of on rumen morphometrics of cull cows immediately stepped up to a high-energy finishing diet.

Forty-five beef cull cows [body weight () = 503 ± 58 kg; body condition score () = 2.1 ± 0.6] were r...