Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Automation and artificial intelligence in radiation therapy treatment planning.

Automation and artificial intelligence (AI) is already possible for many radiation therapy planning and treatment processes with the aim of improving workflows and increasing efficiency in radiation oncology departments. Currently, AI technology is advancing at an exponential rate, as are its applications in radiation oncology. This commentary highlights the way AI has begun to impact radiation th...

Oct 4 2023 37794690

Black box no more: a scoping review of AI governance frameworks to guide procurement and adoption of AI in medical imaging and radiotherapy in the UK.

Technological advancements in computer science have started to bring artificial intelligence (AI) from the bench closer to the bedside. While there is still lots to do and improve, AI models in medical imaging and radiotherapy are rapidly being developed and increasingly deployed in clinical practice. At the same time, AI governance frameworks are still under development. Clinical practitioners in...

Oct 3 2023 37747285
Predicting the therapeutic efficacy of AIT for asthma using clinical characteristics, serum allergen detection metrics, and machine learning techniques.

Bronchial asthma is a prevalent non-communicable disease among children. The study collected clinical data from 390 children aged 4-17 years with asth...

Sep 29 2023 37866086
Comparative Effectiveness Analysis of Lumpectomy and Mastectomy for Elderly Female Breast Cancer Patients: A Deep Learning-based Big Data Analysis.

: To evaluate the comparative effectiveness of treatments, a randomized clinical trial remains the gold standard but can be challenged by a high cost,...

Sep 29 2023 37781001
Theory, Measurement, and Psychometric Properties of Risk and Protective Factors for Drug Misuse Among Adolescents Living on or near the Cherokee Nation Reservation.

A team of tribe-based behavioral health specialists and university-based researchers partnered to implement a cluster randomized trial for the prevent...

Sep 25 2023 38895740
Hair-to-Hair Trichoscopy: An Objective Method to Assess Effectiveness of Botulinum Toxin in a Clinical Trial for Androgenetic Alopecia.

INTRODUCTION: Androgenetic alopecia (AGA) is the most common alopecia affecting both genders leading to a potential decrease in quality of life and se...

Sep 21 2023 38313570
Multimodal Data Fusion to Detect Preknowledge Test-Taking Behavior Using Machine Learning.

In various fields, including college admission, medical board certifications, and military recruitment, high-stakes decisions are frequently made base...

Sep 19 2023 39055093
Perioperative safety and efficacy of robot-assisted total hip arthroplasty in ERAS-managed patients: a pilot study.

AIMS: Robot-assisted total hip arthroplasty (rTHA) boasts superior accuracy in implant placement, but there is a lack of effective assessment in perio...

Sep 18 2023 37723565
Effects of oral melatonin premedication on hemodynamic responses to intubation, anesthetic requirements and postoperative sedation: A randomized trial.

BACKGROUND AND AIMS: Sedative effects of melatonin may have an additive effect on general anesthesia (GA). We compared hemodynamic response to intubat...

Sep 18 2023 38269180
Effect of real-time oxygen consumption versus fixed flow-based low flow anesthesia on oxygenation and perfusion: a randomized, single-blind study.

Although low-flow anesthesia is widely used due to its various advantages, there are concerns about potential and relative hypoxia. Furthermore, oxyge...

Sep 17 2023 39073338
Comparative evaluation of the effectiveness of intracanal and intraoral cryotherapy on postendodontic pain in patients with symptomatic apical periodontitis: A randomized clinical trial.

INTRODUCTION: There is a rising need for controlling postendodontic pain (PEP) without using analgesics and other conventional methods.

Sep 16 2023 38292358
Artificial intelligence revolutionizing drug development: Exploring opportunities and challenges.

By harnessing artificial intelligence (AI) algorithms and machine learning techniques, the entire drug discovery process stands to undergo a profound ...

Sep 15 2023 37712494
Effects of driving pressure-guided ventilation by individualized positive end-expiratory pressure on oxygenation undergoing robot-assisted laparoscopic radical prostatectomy: a randomized controlled clinical trial.

PURPOSE: Patients with robot-assisted laparoscopic radical prostatectomy (RALP) need to be placed in Trendelenburg position, which results in cranial ...

Sep 14 2023 37707572
Real-time monitoring unsafe behaviors of portable multi-position ladder worker using deep learning based on vision data.

INTRODUCTION: Fatal fall from height accidents, especially on construction sites, persist, underscoring the importance of monitoring and managing work...

Sep 14 2023 38081718
Comparison of Clinical Efficacy Between Da Vinci Robot-Assisted Ivor Lewis Esophagectomy and McKeown Esophagectomy for Middle and Lower Thoracic Esophageal Cancer: A Multicenter Propensity Score-Matched Study.

BACKGROUND: We compared the perioperative efficacy and safety of da Vinci robot-assisted Ivor Lewis esophagectomy and McKeown esophagectomy for middle...

Sep 12 2023 37698668
The Assessment of Marcaine Versus Meperidine for Spinal Anesthesia in Anorectal Surgery: A Randomized Clinical Trial.

BACKGROUND: Spinal anesthesia (SA) for the surgical management of chronic anal fissures is favored by surgeons as it provides an early return to daily...

Sep 8 2023 38476991
The efficacy of tranexamic acid in primary anatomic and reverse total shoulder arthroplasty: A systematic review and meta-analysis of level I randomized controlled trials.

PURPOSE: The purpose of this study was to systematically review the available level I evidence regarding the impact of tranexamic acid (TXA) on early ...

Sep 7 2023 39493409
Treatment response to spironolactone in patients with heart failure with preserved ejection fraction: a machine learning-based analysis of two randomized controlled trials.

BACKGROUND: Whether there is a subset of patients with heart failure with preserved ejection fraction (HFpEF) that benefit from spironolactone therapy...

Sep 7 2023 37689023
A study on the appropriate dose of rocuronium for intraoperative neuromonitoring in Da Vinci robot thyroid surgery: a randomized, double-blind, controlled trial.

BACKGROUND: This study was to explore the effect of different doses of rocuronium bromide on neuromonitoring during Da Vinci robot thyroid surgery.

Sep 7 2023 37745708
A framework for proactive safety evaluation of intersection using surrogate safety measures and non-compliance behavior.

In recent years, identifying road users' behavior and conflicts at intersections have become an essential data source for evaluating traffic safety. A...

Sep 4 2023 37672846
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