Oncology/Hematology

Colon Cancer

Latest AI and machine learning research in colon cancer for healthcare professionals.

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Showing 281-300 of 3,597 articles

Integrated transcriptomics, network pharmacology and clinical expression validation reveal the prognostic significance of PANoptosis-related genes in cordycepin-treated lung adenocarcinoma.

BACKGROUND: Studies have shown that PANoptosis is increasingly involved in cancer and cancer treatment. The Cordycepin has also been found to be involved in the development of various cancers. However, relevant research on both in lung adenocarcinoma (LUAD) remains relatively scarce. The present study aims to identify potential prognostic genes in LUAD and elucidate their impact on the prognosis o...

Jun 8 2026 42260221

Deep learning-based automated classification of endometrial lesions in IVF patients using hysteroscopic images.

Endometrial health is a key determinant of female fertility and successful pregnancy outcomes, making the accurate diagnosis of endometrial lesions essential for the success of assisted reproductive technology. While hysteroscopy remains the gold standard for uterine cavity evaluation, interpretation can vary based on clinical expertise. To address this, we developed a deep learning-based clinical...

Jun 6 2026 42251153
Impact of Availability of Computer-Aided Detection Devices on Adenoma Detection During Colonoscopy: A Cluster Randomized Study.

BACKGROUND AND AIMS: Endoscopists' colonoscopy adenoma detection rates (ADR) are inversely associated with their patients' risk of post-colonoscopy co...

Jun 5 2026 42250891
Artificial intelligence for the prediction of prognosis in colorectal cancer patients using routine blood indices.

Overall survival (OS) of colorectal cancer (CRC) patients remains suboptimal, especially in advanced disease. This study aimed to construct and valida...

Jun 5 2026 42249119
Predicting Treatment Response After Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer.

OBJECTIVE: To develop a predictive model for pathological complete response (pCR) after total neoadjuvant therapy (TNT) to inform selection for watch-...

Jun 4 2026 42240534
3D chromatin architecture-related genes orchestrate LUAD evolution and therapy resistance: insights from integrative machine learning and spatial single-cell mapping.

BACKGROUND: Lung adenocarcinoma (LUAD) is a prevalent and lethal malignancy. The three-dimensional (3D) chromatin architecture significantly influence...

Jun 4 2026 42240917
Novel technologies for gastrointestinal cancer detection: a systematic review and meta-analysis of diagnostic accuracy.

INTRODUCTION: Gastrointestinal (GI) cancers account for a quarter of all cancers and one-third of cancer-related deaths worldwide. Novel diagnostic ap...

Jun 4 2026 42242200
Plasma signals of lung tumor promotion for molecular cancer prevention.

Predicting lung cancer risk would enhance prevention trials. Although the Canakinumab Anti-inflammatory Thrombosis Outcome Study (CANTOS) trial demons...

Jun 4 2026 42242224
Construction and validation of a machine learning-based prediction model for social isolation in patients with colorectal cancer after stoma surgery.

OBJECTIVE: To investigate the current status and influencing factors of social alienation in patients with enterostomy after colorectal cancer surgery...

Jun 4 2026 42243692
Multi-omic biomarkers of neoadjuvant treatment response in rectal cancer: A narrative review.

BACKGROUND: Neoadjuvant treatment response in rectal cancer is highly heterogeneous, complicating patient selection for organ-preservation strategies....

Jun 3 2026 42250371
Integrative Network Toxicology and Machine Learning Identify AKR1C3 as a Candidate Functional Target of Cypermethrin in Colorectal Cancer.

The potential contribution of foodborne pesticide residues to colorectal cancer (CRC) remains insufficiently understood. In this study, we integrated ...

Jun 3 2026 42242413
A multimodal prediction framework for colorectal cancer peritoneal metastasis: CT-based tumor and adipose tissue analysis.

Accurate preoperative assessment of CT-occult peritoneal metastasis (PM) in colorectal cancer is critical for clinical decision-making. This study dem...

Jun 3 2026 42234110
Learning and deskilling effects of artificial intelligence in colonoscopy among endoscopists with different levels of experience: a pragmatic, prospective trial.

BACKGROUND: The effect of computer-aided detection (CADe) on performance of endoscopists with different experience levels is not well understood. This...

Jun 3 2026 42235541
Prospective germline exome and machine learning-based risk score identify predictive and prognostic biomarkers of immunotherapy outcomes in advanced non-small cell lung cancer.

BACKGROUND: Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape of advanced non-small cell lung cancer (NSCLC). However, a su...

Jun 2 2026 42231301
Associations of serum per- and polyfluoroalkyl substances (PFAS) mixture with the risk of chronic diseases: evidence from single‑ , multi-pollutant, and machine learning models.

Per- and polyfluoroalkyl substances (PFAS) are persistent chemicals commonly found in consumer products. Despite growing concern over their health eff...

Jun 2 2026 42228134
Organ-Specific Cancer-Associated Fibroblast Subtypes Across the Digestive System Linked to Cancer Hallmarks.

Cancer-associated fibroblasts (CAFs) are major stromal components of the tumor microenvironment (TME) and play diverse roles in gastrointestinal (GI) ...

Jun 1 2026 42222902
In-Depth Plasma Proteomics Identifies SNCA as a Discriminating Biomarker of PDAC.

Pancreatic ductal adenocarcinoma (PDAC) carries a poor prognosis largely due to lack of efficient diagnostic means. We applied mass spectrometry-based...

Jun 1 2026 42223356
Integrative multi-omics analysis identifies a circadian rhythm-associated gene signature for prognosis and therapeutic stratification in lung adenocarcinoma.

BACKGROUND/OBJECTIVES: Circadian rhythm disruption is increasingly implicated in tumor progression and therapy resistance. However, its prognostic val...

Jun 1 2026 42223738
A risk stratification framework based on ammonia-induced cell death signatures for prognostic assessment and therapeutic insights in colorectal cancer.

BACKGROUND: Ammonia, which was traditionally regarded as a metabolic by-product, has more recently emerged as a crucial regulator of tumor metabolism ...

Jun 1 2026 42223795
Feasibility and Preliminary Effectiveness of the ChulaCancer Mobile Chatbot for Supportive Care of Patients With Breast or Colorectal Cancer Receiving Chemotherapy: Pilot Randomized Controlled Trial.

BACKGROUND: Chemotherapy-related toxicities often lead to unscheduled health care use and diminished quality of life. Digital health interventions, su...

Jun 1 2026 42224667
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