Oncology/Hematology

Colon Cancer

Latest AI and machine learning research in colon cancer for healthcare professionals.

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Showing 21-40 of 3,597 articles

Quality, transparency, and readability of AI chatbot responses for patient counseling in robot-assisted colorectal cancer resection: a cross-sectional evaluation.

Robot-assisted colorectal cancer resection (RACR) has emerged as a preferred surgical approach for mid-to-low rectal tumors, yet patients often struggle to find accessible, accurate information about this complex procedure. Artificial intelligence (AI) chatbots increasingly serve as lay-friendly health information sources, but whether they deliver counseling of sufficient quality, transparency, an...

Aug 28 2026 42663795

Leveraging artificial intelligence in the early detection of ovarian cancer: Development and validation of a risk prediction model.

OBJECTIVE: To develop and validate a predictive tool to estimate the risk of ovarian cancer in a screening setting. METHODS: Machine learning was leveraged to create a predictive model for ovarian cancer diagnosis within one year of screening. Data from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial were used in model creation. Participants in this trial were comprised of female...

Aug 28 2026 42664614
Lactylation-related immune-metabolic dysregulation defines prognostic and therapeutic stratification in lung adenocarcinoma.

BACKGROUND: Lactylation links lactate metabolism with inflammatory signaling and immune regulation in tumors. However, its cellular distribution and t...

Aug 28 2026 42664787
Comment on "Artificial intelligence construction: a review of the bridge between CT imaging features of lung ground-glass nodules adenocarcinoma and carcinogenic driver genes".

Xue and Chen et al.'s review connects AI-derived CT features of lung ground-glass nodule adenocarcinoma to driver gene status. Three aspects are missi...

Aug 27 2026 42661070
Semi-Supervised Domain Adaptation with Latent Diffusion for Pathology Image Classification.

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches eith...

Aug 27 2026 42658697
Detection of Pancreatic Cancer via Specific Metabolite Markers: A Metabolomics Approach.

BACKGROUND AND AIMS: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies worldwide because most patients are diagnosed...

Aug 26 2026 42661978
Deciphering Post-surgery Gut Microbial Dynamics in Colorectal Cancer through Multi-cohort Machine Learning.

Surgical resection, and its associated bowel preparation, remain the primary treatment for colorectal cancer (CRC), yet the associated effects on post...

Aug 26 2026 42645508
Association between body composition and recurrence in stage II-III colon cancer: a retrospective cohort study.

INTRODUCTION: Colorectal Cancer (CRC) is a common cause of cancer death and prognostic factors are used to determine management. Patients with advance...

Aug 26 2026 42648596
Tissue-Agnostic Cellular Morphometric Biomarkers for Risk-Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers.

While precision oncology increasingly adopts tissue-agnostic paradigms, current strategies remain heavily reliant on molecular alterations, with limit...

Aug 25 2026 42639854
Integrated Multi-Omics Analysis of Gut Microbiota-Associated Metabolites and Related Host Molecular Signatures in Cervical Squamous Cell Carcinoma.

Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) is a common female malignancy. Gut microbiota and metabolites are critical reg...

Aug 25 2026 42640410
Predicting Synchronous Liver Metastasis in Pancreatic Cancer Using CT Radiomics and Clinical Features: A Machine Learning Approach.

RATIONALE AND OBJECTIVES: To address the challenge of preoperative prediction of synchronous liver metastasis (LM) in pancreatic cancer (PC), we devel...

Aug 25 2026 42642322
Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer-Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy.

Paclitaxel (PTX) chemotherapy is constrained by an "immunomodulatory paradox," where antitumor Type I Interferon (IFN-I) activation is coupled with de...

Aug 24 2026 42635620
An ICD gene set-derived immune contexture signature for colorectal cancer prognosis: integrated single-cell and bulk transcriptomic analysis with external validation.

Immunogenic cell death (ICD) links tumor cell demise with antitumor immunity, but the transcriptional features associated with ICD gene expression pat...

Aug 24 2026 42636619
Multidimensional 5-hydroxymethylcytosine features in cell-free DNA enable the detection, staging and subtyping of pancreatic ductal adenocarcinoma.

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignant cancer with limited biomarkers for early detection and disease stratification. He...

Aug 24 2026 42638133
CDKN3, PKP2, ADM, MS4A1, FAM83A, and DKK1 Define a Posttranslational Modification (PTM)-Associated Prognostic Model for Lung Adenocarcinoma.

INTRODUCTION: Posttranslational modification (PTM) plays an important role in protein regulation and may influence tumor initiation and progression. H...

Aug 24 2026 42638932
Precision Pancreatic Cancer Care: From Early Detection to Adaptive Precision Oncology.

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains highly lethal, and genome-centric precision oncology shows limited impact due to low actio...

Aug 22 2026 42632056
Identification of Mitotic Catastrophe-related Prognostic Genes in Lung Adenocarcinoma via Transcriptome Analysis.

Lung adenocarcinoma (LUAD), the most common lung cancer subtype, exhibits a poor prognosis. Although mitotic catastrophe can be induced in LUAD, leadi...

Aug 21 2026 42631570
AI-assisted second forward-view examination of the right colon significantly improves the adenoma detection rate: a multicenter randomized controlled trial.

BACKGROUND: Adenomas in the right colon are likely to be missed during colonoscopy because of anatomical complexity and lesion characteristics. Althou...

Aug 20 2026 42633947
Mouth-to-gut microbial transmission signatures enable robust, non-invasive diagnosis of gastrointestinal cancers.

The human microbiome is spatially compartmentalized, yet oral bacteria can ectopically colonize distal sites such as the gut, potentially influencing ...

Aug 20 2026 42624114
Advanced gene editing technologies for oncology mechanisms, applications, and clinical implementation.

Advanced gene editing tools have transformed oncology by facilitating precise molecular therapies aimed at the hereditary basis of cancer. This thorou...

Aug 20 2026 42624898
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