Colon Cancer

Development of a Diagnostic Model for Pancreatic Ductal Adenocarcinoma Using Machine Learning and Blood-Based miRNAs.

INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) has the lowest survival rate among all major cancers due to a lack of symptoms in early stages, early detection tools, and optimal therapies for late-stage patients. Thus, effective and non-invasive diagnostic tests are greatly needed. Recently, circulating miRNAs have been reported to be altered in PDAC. They are promising biomarkers because o...

Artificial Intelligence and cancer: Profile of registered clinical trials.

Artificial Intelligence (AI) has made significant strides due to advancements in processing algorithms and data availability. Recent years have shown a resurgence in AI, driven by breakthroughs in deep machine learning. AI has attracted particular interest in the medical sector, especially in the field of personalized medicine, which for example uses large-scale genomic and molecular data to predi...

Deciphering colorectal cancer radioresistance and immune microrenvironment: unraveling the role of EIF5A through single-cell RNA sequencing and machine learning.

BACKGROUND: Radiotherapy (RT) is a critical component of treatment for locally advanced rectal cancer (LARC), though patient response varies significa...

Enhancing metastatic colorectal cancer prediction through advanced feature selection and machine learning techniques.

BACKGROUND AND AIMS: Colorectal cancer (CRC) is the third most prevalent cancer globally, posing a significant challenge due to its high rate of metas...

A Deep Learning Approach for the Identification of the Molecular Subtypes of Pancreatic Ductal Adenocarcinoma Based on Whole Slide Pathology Images.

Delayed diagnosis and treatment resistance result in high pancreatic ductal adenocarcinoma (PDAC) mortality rates. Identifying molecular subtypes can ...

Integrated machine learning survival framework to decipher diverse cell death patterns for predicting prognosis in lung adenocarcinoma.

Various forms of programmed cell death (PCD) collectively regulate the occurrence, development and metastasis of tumors. Nevertheless, a comprehensive...

Deciphering Dormant Cells of Lung Adenocarcinoma: Prognostic Insights from O-glycosylation-Related Tumor Dormancy Genes Using Machine Learning.

Lung adenocarcinoma (LUAD) poses significant challenges due to its complex biological characteristics and high recurrence rate. The high recurrence ra...

Use of artificial intelligence improves colonoscopy performance in adenoma detection: a systematic review and meta-analysis.

BACKGROUND AND AIMS: Artificial intelligence (AI) is increasingly used to improve adenoma detection during colonoscopy. This meta-analysis aimed to pr...

Identification of cancer stem cell-related genes through single cells and machine learning for predicting prostate cancer prognosis and immunotherapy.

BACKGROUND: Cancer stem cells (CSCs) are a subset of cells within tumors that possess the unique ability to self-renew and give rise to diverse tumor ...

Machine Learning Based on Clinical Information and Integrated CT Radiomics to Predict Local Recurrence of Stage Ia Lung Adenocarcinoma after Microwave Ablation.

PURPOSE: To develop and compare 3 different machine learning-based models of clinical information and integrated radiomics features predicting the loc...

A prognostic biomarker of disulfidptosis constructed by machine learning framework model as potential reporters of pancreatic adenocarcinoma.

BACKGROUND: Pancreatic adenocarcinoma (PAAD), known for its high lethality, has not been thoroughly explored in terms of its mechanisms and patterns o...

Polar contrast attention and skip cross-channel aggregation for efficient learning in U-Net.

The performance of existing lesion semantic segmentation models has shown a steady improvement with the introduction of mechanisms like attention, ski...

A Computer Vision Algorithm to Predict Superior Mesenteric Artery Margin Status for Patients With Pancreatic Ductal Adenocarcinoma.

OBJECTIVE: To evaluate the feasibility of developing a computer vision algorithm that uses preoperative computed tomography (CT) scans to predict supe...

Enhancing colorectal cancer histology diagnosis using modified deep neural networks optimizer.

Optimizers are the bottleneck of the training process of any Convolutionolution neural networks (CNN) model. One of the critical steps when work on CN...

An end-to-end deep learning method for mass spectrometry data analysis to reveal disease-specific metabolic profiles.

Untargeted metabolomic analysis using mass spectrometry provides comprehensive metabolic profiling, but its medical application faces challenges of co...

An efficient colorectal cancer detection network using atrous convolution with coordinate attention transformer and histopathological images.

The second most common type of malignant tumor worldwide is colorectal cancer. Histopathology image analysis offers crucial data for the clinical diag...

Predictive Study of Machine Learning-Based Multiparametric MRI Radiomics Nomogram for Perineural Invasion in Rectal Cancer: A Pilot Study.

This study aimed to establish and validate the efficacy of a nomogram model, synthesized through the integration of multi-parametric magnetic resonanc...

Polyp detection with colonoscopy assisted by the GI Genius artificial intelligence endoscopy module compared with standard colonoscopy in routine colonoscopy practice (COLO-DETECT): a multicentre, open-label, parallel-arm, pragmatic randomised controlled trial.

BACKGROUND: Increased polyp detection during colonoscopy is associated with decreased post-colonoscopy colorectal cancer incidence and mortality. The ...

The Usefulness of Low-Kiloelectron Volt Virtual Monochromatic Contrast-Enhanced Computed Tomography with Deep Learning Image Reconstruction Technique in Improving the Delineation of Pancreatic Ductal Adenocarcinoma.

To evaluate the usefulness of low-keV multiphasic computed tomography (CT) with deep learning image reconstruction (DLIR) in improving the delineation...

Foundation models in gastrointestinal endoscopic AI: Impact of architecture, pre-training approach and data efficiency.

Pre-training deep learning models with large data sets of natural images, such as ImageNet, has become the standard for endoscopic image analysis. Thi...