Infectious Disease

COVID-19

Latest AI and machine learning research in covid-19 for healthcare professionals.

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Design and structure of protein cages based on helical fusion and machine learning

Self-assembling protein cages are versatile nanoscale architectures with broad applications in drug ...

Transcriptomics-Conditioned Virtual Tissue Synthesis via Diffusion Transformers

Spatial transcriptomics couples hematoxylin and eosin (H&E) tissue morphology with spatially resolve...

Pansoma, a machine learning tool for identifying somatic variants using pangenome graphs

Somatic variant calling, the identification of mutations in non-germline cells acquired over an indi...

Mapping Genetic Risk Associations to Cellular Contexts via Deep Learning and Biological Ontologies

Translating genome-wide association studies (GWAS) signals into trait-relevant cellular contexts rem...

Sequence-Based Prioritization of Promoter Regulatory Variants in Colorectal Cancer Using a DNA Foundation Model

Noncoding regulatory variants contribute to colorectal cancer (CRC) susceptibility, yet their functi...

Random Forest Model for Predicting Post-Lockdown Antenatal Depression Risk: A Cross-Sectional Study of Pregnant Women in China

Background As lockdown measures was eased, pregnant women faced an elevated risk of COVID-19 infecti...

Beyond natural amino acids: Extending immunogenicity risk assessment to non-canonical peptide drugs through chemical feature encoding

Peptide therapeutics are increasingly used to treat challenging diseases, but immunogenicity risks l...

Inducible lipid storage and steatosis in the human choroid plexus associated with age and adiposity

Cells that store lipids for other cells or organs can contain ''giant'' or large lipid droplets (LLD...

MedVol-R1: Reward-Driven Evidence Grounding for Volumetric Reasoning Segmentation

Volumetric Reasoning Segmentation (VRS) aims to segment a target region in a 3D medical scan from a ...

Not All Tokens Matter Equally: Dynamic In-context Vector Distillation with Decisive-Token Supervision for Long-form Medical Report Generation

Distilling demonstration effects into hidden-space interventions offers a lightweight alternative to...

Feedforward 3D Editing Learns from Semantic-Part Transformation

3D editing is a fundamental capability for scalable 3D content creation. While image editing has rap...

Co-folding model guided by structural proteomics

Protein structure generative models excel at predicting single protein static structures from sequen...

Genomic Diagnostics for Drug-Resistant Mycobacterium tuberculosis: Computational Prediction of Antimicrobial Resistance

Tuberculosis remains a leading cause of infectious disease mortality, and the continued emergence of...

Weakly Supervised Camouflaged Object Detection Based on the SAM Model and Mask Guidance

Camouflaged object detection (COD) from a single image is a challenging task due to the high similar...

Event-based Batting Impact Estimation

Estimating the precise timing of batting impact is crucial for understanding the rapid sensorimotor ...

DeCoDrift: Stabilizing Decoder Coupling in Closed-Loop Foundation Segmentation

Foundation segmentation models such as Segment Anything Model (SAM) are now routinely used in iterat...

Pixel-Level Pavement Distress Assessment Using Instance Segmentation

Automated pavement distress assessment requires more than image-level classification or coarse bound...

OpenSplice: the impact of half a million mutations on the alternative splicing of 600 human exons

Alternative splicing of mRNA precursors is an important step in gene regulation and a major mechanis...

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