Infectious Disease

COVID-19

Latest AI and machine learning research in covid-19 for healthcare professionals.

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FiRe: Fixed-Noise Refinement for Visual Counterfactual Explanations

Visual counterfactual explanations aim to change classifier decisions through realistic and localized edits while preserving decision-irrelevant content. Existing DDPM-based methods typically perform classifier-guided editing along a long reverse denoising trajectory. The changing noise levels make semantic editability and spatial control difficult to balance, and the editable state is noisy, wher...

Aug 9 2026 2608.08664v1

Assessing Computational Models for Pharmacogenomic Variant Interpretation

Accurately predicting the effects of pharmacogenomic variants is essential for the development of personalized therapeutic strategies, as genetic variability can influence drug response differently across patients. Here, we assessed several computational approaches using a dataset of pharmacogenomic variants with either clinical annotations or functional characterization by deep mutational scannin...

Mapping the Pandemics Echo: Dynamic Narrative Detection and Spatio-Temporal Sentiment Modeling of COVID-19 Discourse on Twitter

The COVID-19 pandemic triggered an unprecedented volume of real-time discourse on social media platforms, with Twitter serving as a global forum for p...

Structure-aware deep learning predicts influenza antigenicity and guides vaccine strain recommendation

The continuous accumulation of genetic mutations in influenza A viruses (IAVs) drives antigenic drift, necessitating precise antigenic prediction for ...

A confound-diagnostic toolkit for in silico perturbation with single-cell foundation models

Deleting a gene token from a cell's input sequence offers a convenient native strategy for in silico perturbation, but the resulting embedding delta m...

PGViS: Personal Genome Variant interpretation Score for lung cancer genomes

Inherited lung cancer risk arises from both protein-coding and non-coding germline variants, but the functional non-coding component is largely unchar...

Universal Concept Disruption for SAM3 Image Segmentation

SAM3 extends promptable segmentation from geometry-driven mask prediction to open-vocabulary concept segmentation, where a text-conditioned grounding ...

Aug 6 2026 2608.05983v1
TLNM: Externally Validated Tooth Detection, Numbering and Segmentation from Smartphone Photographs Using Mask R-CNN

Oral health issues affect billions globally, but the cost and limited access to professional dental care hinder preventive oral healthcare. Research r...

Aug 6 2026 2608.06275v1
Dual-Specific Antibody Design Using Artificial Intelligence

Multibodies, or "two-in-one" Immunoglobulin G (IgG) antibodies, are standard symmetrical IgG molecules engineered to competitively bind more than one ...

HexMIL: Hierarchical Attention MIL for Ante-Hoc Explainable Detection of AI-Manipulated CT Volumes

The emergence of medical deepfakes, i.e., medical images manipulated by deep generative models, poses a significant threat to clinical workflows. Howe...

Aug 5 2026 2608.05101v1
SIGNPOST-Bench: Benchmarking Text-Vision Conflict Resolution in Multimodal Large Language Models

Multimodal large language models (MLLMs) make grounded predictions in real-world scenes by combining visual and textual cues, yet existing benchmarks ...

Aug 4 2026 2608.04244v1
Humanized Anti-PD-1 Antibodies Generated Using The Conditional Kernel-Elastic Autoencoder

The human immune system excels at generating highly effective antibodies through natural selection and somatic hypermutation, but adapting these antib...

EditFlow3D: Automated Local Editing of 3D Assets with Trajectory Preservation

Controllable local editing of 3D assets requires precise target localization and appropriate visual guidance. However, existing methods lack a simple ...

Aug 4 2026 2608.03179v1
TimeRLM: Recursive Language Models Enable Precise Anomaly Localization in Long-Context Time-Series

Precise anomaly localization over long-context time series is a crucial task in monitoring applications across clinical care, industrial operations, f...

Aug 4 2026 2608.03391v1
SRAP: SVD-Refined Adversarial Perturbations for Imperceptible Face-Swap Defense

Deepfake technologies pose increasing threats to facial privacy and identity security, motivating proactive defenses that protect facial images before...

Aug 4 2026 2608.03395v1
Detecting Pose Estimation Failures via Keypoint Self-Consistency

One common approach to pose estimation involves predicting object keypoints in an image, followed by using Perspective-n-Point algorithms to compute t...

Aug 4 2026 2608.03516v1
Can LLMs Test Terminal User Interfaces?

Terminal User Interfaces (TUIs) combine the stateful, screen-oriented behaviour of GUIs with terminal deployment and are now common in developer tools...

Aug 4 2026 2608.03743v1
Better, Stronger, Faster, and Broader: Structured All-Mask Prediction for MLLM-Based Segmentation

MLLM-based segmentation faces a core segmentation trilemma: high segmentation performance, preserved dialogue ability, and fast inference. Embedding-p...

Aug 3 2026 2608.02791v1
Localize, Don't Beautify: Client-Side Control of Image-Editing APIs for Cosmetic Surgery Previews

Ask a commercial image editor to preview a cosmetic procedure and it will often change more of the face than the request names: a nose edit can also s...

Aug 3 2026 2608.02841v1
Variantscape: Large Language Model-Driven Mining of Biomedical Literature for Clinical Interpretation of Cancer Variants

Background: Precision oncology relies on accurate interpretation of tumour-detected gene variants, to guide personalized treatment decisions. However,...

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