Infectious Disease

COVID-19

Latest AI and machine learning research in covid-19 for healthcare professionals.

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Convolutional neural network model to predict causal risk factors that share complex regulatory features.

Major progress in disease genetics has been made through genome-wide association studies (GWASs). On...

Dec 2019 31598692
Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body.

Reliable detection of disseminated tumor cells and of the biodistribution of tumor-targeting therape...

Dec 2019 31835038
Functional interpretation of genetic variants using deep learning predicts impact on chromatin accessibility and histone modification.

Identifying functional variants underlying disease risk and adoption of personalized medicine are cu...

Nov 2019 31544924
Machine-learned analysis of the association of next-generation sequencing-based genotypes with persistent pain after breast cancer surgery.

Cancer and its surgical treatment are among the most important triggering events for persistent pain...

Oct 2019 31107411
Artificial Intelligence Estimates the Importance of Baseline Factors in Predicting Response to Anti-PD1 in Metastatic Melanoma.

OBJECTIVE: Prognosis of patients with metastatic melanoma has dramatically improved over recent year...

Aug 2019 31261257
Uncovering the mouse olfactory long non-coding transcriptome with a novel machine-learning model.

Very little is known about long non-coding RNAs (lncRNAs) in the mammalian olfactory sensory epithel...

Aug 2019 31321403
Using the structure of genome data in the design of deep neural networks for predicting amyotrophic lateral sclerosis from genotype.

MOTIVATION: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by aberrations...

Jul 2019 31510706
Automatic PAP Mask Sizing with an Error Correcting Autoencoder.

We present the use of an error correcting autoencoder stage to a convolutional neural network model ...

Jul 2019 31946674
Antibody interface prediction with 3D Zernike descriptors and SVM.

MOTIVATION: Antibodies are a class of proteins capable of specifically recognizing and binding to a ...

Jun 2019 30395191
Multi-purpose Robotic Training Strategies for Neurorehabilitation with Model Predictive Controllers.

One of the main challenges in robotic neuroreha-bilitation is to understand how robots should physic...

Jun 2019 31374721
Semi-supervised learning of a nonnative phonetic contrast: How much feedback is enough?

Semi-supervised learning refers to learning that occurs when feedback about performance is provided ...

May 2019 31062297
Deep repeat resolution-the assembly of the Drosophila Histone Complex.

Though the advent of long-read sequencing technologies has led to a leap in contiguity of de novo ge...

Feb 2019 30476267
PreMedKB: an integrated precision medicine knowledgebase for interpreting relationships between diseases, genes, variants and drugs.

One important aspect of precision medicine aims to deliver the right medicine to the right patient a...

Jan 2019 30407536
Vision-referential speech enhancement of an audio signal using mask information captured as visual data.

This paper describes a vision-referential speech enhancement of an audio signal using mask informati...

Jan 2019 30710939
Outgroup Machine Learning Approach Identifies Single Nucleotide Variants in Noncoding DNA Associated with Autism Spectrum Disorder.

Autism spectrum disorder (ASD) is a heritable neurodevelopmental disorder affecting 1 in 59 children...

Jan 2019 30864328
An enhanced workflow for variant interpretation in UniProtKB/Swiss-Prot improves consistency and reuse in ClinVar.

Personalized genomic medicine depends on integrated analyses that combine genetic and phenotypic dat...

Jan 2019 30937429
The 18th FRAME Annual Lecture, October 2019: Human Trials in Pharmacology.

Safety and efficacy testing is a crucial part of the drug development process, and several different...

Jan 2019 32090621
ASSOCIATION OF FOXP3 GENE VARIANTS WITH RISK OF HASHIMOTO'S THYROIDITIS AND CORRELATION WITH ANTI-TPO ANTIBODY LEVELS.

CONTEXT: Regulatory T cells (Tregs) have critical roles in preventing autoimmune diseases such as Ha...

Jan 2019 32377237
[The β2GPI/aβ2GPI inhibits phagocytosis of oxidized low-density lipoprotein in THP-1 macrophages via activating TLR4].

Objective To investigate the effects of β2 glycoprotein I/anti-β2 glycoprotein I antibody complex (β...

Dec 2018 30626470
The Comparison Between Different Immunoassays for Serum Carbohydrate Antigen (CA 19-9) Concentration Measurement.

INTRODUCTION: The carbohydrate antigen (CA 19-9) is a marker for pancreatic and colorectal carcinoma...

Dec 2018 30692705
Platelet mitochondrial cytochrome c oxidase subunit I variants with benzene poisoning.

BACKGROUND: Chronic benzene poisoning (CBP) is one of the most common chronic occupational poisoning...

Dec 2018 30746226
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