Infectious Disease

COVID-19

Latest AI and machine learning research in covid-19 for healthcare professionals.

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DeepRank-Ab: a scoring function for antibody-antigen complexes based on geometric deep learning.

Gaining structural insights into antibody-antigen interactions is essential for understanding immune recognition and therapeutics design. Accurately modeling these complexes remains challenging for both physics-based approaches and AI-based, co-folding methods such as AlphaFold3. These methods not only struggle to generate near-native conformations, but, more critically, often fail to rank those c...

Jun 2 2026 42230751

Landscape of T-cell bispecific antibodies in cancer therapy: therapeutic strategies, challenges and future prospection.

T-cell bispecific antibodies (TCBs), a specialized subclass of bispecific antibodies (BsAbs), are engineered to simultaneously engage T cells and tumor cells by binding two distinct antigens-or two epitopes on a single antigen-thereby redirecting cytotoxic T lymphocytes to eliminate malignant cells. These agents enhance anti-tumor immunity through dual mechanisms: direct activation of T cell recep...

Jun 1 2026 42226254
[A nomogram combining ultrasound radiomics and clinical features for predicting pathological invasiveness of papillary thyroid carcinoma].

OBJECTIVES: To develop a nomogram model combining ultrasound radiomics and clinical features and to evaluate its predictive value for pathological inv...

Jun 1 2026 42226496
Evolution of PM2.5 chemical composition during summer new particle formation in a coastal city in the Yangtze River Delta: insights from pollution episodes, machine learning, and air mass origins.

To investigate the influence of O3 on new particle formation (NPF) events and associated changes in PM2.5 chemical composition, an observation campaig...

Jun 1 2026 42229564
Building Machine Learning Model for Emotional Analysis of Twitter (X) Discourse during Flood Disasters: A Case Study of Chennai, India.

OBJECTIVE: The aim of this study is to develop disaster specific classification model specific to India, that extracts population emotional states dur...

Jun 1 2026 42219928
Targeting Type 2 and Non-type 2 Asthma: Emerging Biologics and Personalized Strategies.

PURPOSE OF REVIEW: Asthma continues to pose a serious global health issue affecting billions of people and causing significant morbidity. It is immuno...

Jun 1 2026 42223828
Human and Robot Assistance for Cognitive Load in Younger and Older Adults: Multimodal Within-Subject Experimental Study.

BACKGROUND: Maintaining cognitive efficiency and independence is a central goal of healthy aging. Socially assistive robots (SARs) are increasingly pr...

Jun 1 2026 42224389
Designing the Future of Hemostasis.

Bleeding disorders arising from dysfunctional platelet-protein interactions pose a significant clinical challenge due to their heterogeneity and compl...

Jun 1 2026 42225137
Bayesian convolutional front-end based uncertainty-aware hybrid quantum-classical image classification.

Quantum machine learning on noisy intermediate-scale quantum (NISQ) devices often suffers from noise sensitivity, small-data overfitting, and miscalib...

Jun 1 2026 42225773
Improving seismic fault detection through fault-balanced patch extraction and deep learning networks (UNet, Efficient-UNet, and VGG19-UNet).

Accurate seismic fault detection is essential for reliable structural interpretation, reservoir characterization, and drilling risk mitigation. Conven...

Jun 1 2026 42225901
Application of delta radiomics based on cone-beam computed tomography in predicting radiotherapy efficacy for nasopharyngeal carcinoma.

PURPOSE: To investigate the value of cone-beam computed tomography (CBCT)-based delta radiomics for predicting short-term radiotherapy (RT) response i...

Jun 1 2026 42225987
Leveraging clinical epidemiology concepts to strengthen machine learning fairness evaluations.

OBJECTIVES: The increasing use of machine learning (ML) in clinical care makes fairness a central issue. Fairness, defined as the absence of dispariti...

Jun 1 2026 41947590
From Theory to Practice: Which Biomarkers Are Ready for Predicting Response in Advanced HCC?

Systemic therapies for advanced hepatocellular carcinoma (HCC) have expanded considerably with the advent of tyrosine kinase inhibitors, immune checkp...

Jun 1 2026 42126023
Screening and comprehensive analysis of endoplasmic reticulum stress-related biomarkers in atherosclerosis.

Atherosclerosis (AS) is a chronic inflammatory vascular disorder in which endoplasmic reticulum stress (ERS) plays a crucial regulatory role. However,...

Jun 1 2026 42224166
SHARP: a hybrid metaheuristic approach for intelligent robotic path planning.

Robotic path planning is a fundamental requirement for autonomous navigation, where a robot must reach a target while avoiding obstacles and producing...

May 31 2026 42225711
Rapid autofluorescence based 3D optical imaging of the pancreatic cancer milieu at mesoscopic scale - stain-free volumetric segmentation.

Although major advances have been made in the field of mesoscopic imaging and associated tissue clearing protocols, these applications are greatly cha...

May 31 2026 42225812
HAMNet: Hierarchical Multi-scale Attention Network for precise disease detection in pearl millet using spatial fusion.

Pearl millet is a vital crop in arid and semi-arid regions, but its productivity is significantly impacted by fungal and bacterial diseases. Tradition...

May 31 2026 42219448
A Multidimensional Integrated Strategy for Identifying Anti-thrombotic Quality Markers(Q-Markers) in Taohong Siwu Decoction through Combined Analysis of Chemical Profiling, Bioactivity, and Pharmacodynamic Efficacy.

ETHNOPHARMACOLOGICAL RELEVANCE: Taohong Siwu Decoction (TSD), originating from the Qing Dynasty medical text Gynecology Ice Mirror, is a representativ...

May 29 2026 42217590
Development and validation of a serum microRNA biomarker panel for bovine Johne's disease.

Johne's disease (JD) is a chronic wasting disease of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP). For decades, JD manage...

May 29 2026 42217777
AI-MIRACLE: Artificial Intelligence and MultIpaRAmetric MRI Predict CLinical OutcomEs to Neoadjuvant Immunotherapy in Patients with Muscle-invasive Bladder Cancer Undergoing Radical Cystectomy.

BACKGROUND AND OBJECTIVE: Neoadjuvant immune-checkpoint inhibitors (ICIs) in muscle-invasive bladder cancer (MIBC) were tested in patient's ineligible...

May 29 2026 42215334
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