Infectious Disease

COVID-19

Latest AI and machine learning research in covid-19 for healthcare professionals.

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Gene Specific Pathogenicity Predictor for Chromatin Remodeling BAF Complex-Associated Neurodevelopmental Disorders.

Advancements in whole genome sequencing have increased the number of variants of uncertain significance (VUS) identified in human genomes. This has created a diagnostic bottleneck for genetic counselors tasked with sifting through these variants and determining those most likely to be causative for a patient's clinical presentation. Machine learning (ML) tools can aid in identifying pathogenic var...

Feb 28 2026 41764075

Harnessing Phage-Based Nanosensors for Advancing Ultrasensitive Point-of-Care Detection of Foodborne Pathogenic Bacteria.

The persistent global challenge of foodborne pathogens necessitates the development of ultrasensitive point-of-care (POC) detection technologies. However, conventional methods for detecting foodborne pathogens, such as culture-based and nucleic-acid-based techniques, are often limited by complex procedures and reliance on sophisticated instrumentation, respectively. Although immunoassays are more ...

Feb 28 2026 41762130
Use of Bioinformatics and Machine Learning to Identify Circadian Rhythm Disruption- and Endoplasmic Reticulum Stress-Associated Biomarkers in Nonalcoholic Fatty Liver Disease.

Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disorder closely linked to circadian rhythm disruption (CRD) and endoplasmic reticu...

Feb 28 2026 41731716
AI-driven forecasting of Vibrio vulnificus in the Southern Baltic Sea using high-resolution data.

Vibrio vulnificus poses a growing public health risk in the brackish Baltic Sea, where rising summer sea temperatures can create optimal conditions fo...

Feb 27 2026 41795366
SAFEGUARD: Transforming Military Suicide Prevention Through Predictive Analytics and Targeted Interventions.

PURPOSE OF REVIEW: Machine learning predictive modeling can support scalable prevention of suicide-related behavior (SRB). SAFEGUARD is a three-pronge...

Feb 27 2026 41758437
Genetic insights into migraine pathophysiology: COX-2 1195 A>G (rs689466) and COX-2 765 G>C (rs20417) polymorphisms and their clinical implications.

OBJECTIVES: This study aimed to investigate the association of COX-2 gene polymorphisms with key clinical features of migraine, including headache ons...

Feb 27 2026 41758606
Delta radiomics-based nomogram for preoperative prediction vessels encapsulating tumor clusters (VETC) and prognosis in hepatocellular carcinoma using dynamic contrast-enhanced CT.

BACKGROUND: Vessels encapsulating tumor clusters (VETC) serve as a crucial adverse prognostic indicator in hepatocellular carcinoma (HCC). This study ...

Feb 27 2026 41761127
Fcer1g and St3gal1: Macrophage-associated angiogenesis biomarkers and therapeutic targets in sepsis-induced acute lung injury.

BACKGROUND: Acute lung injury (ALI) involves the release of growth factors and inflammatory mediators from damaged pulmonary tissues, fostering endoth...

Feb 27 2026 41758834
Distinguishing post-COVID from long-COVID in adults: Development and validation of a biomarker signature using targeted proteomics and machine learning in a cross-sectional observational study.

BACKGROUND: COVID-19 can have diverse clinical manifestations, ranging from asymptomatic infection to critical illness with multiorgan involvement. Wh...

Feb 27 2026 41758880
Acute respiratory infection (COVID-19) risk prediction in travelers: A random forest model.

BACKGROUND: Early screening during outbreaks of acute respiratory infections (ARIs) is critical for controlling disease spread among international tra...

Feb 26 2026 41810134
Computational hybrid framework integrating clinical-mutation profiling and physics-based simulations to predict structural tolerance of Bruton tyrosine kinase (BTK) and sustained ARQ 531 binding.

Bruton tyrosine kinase (BTK) is a non-receptor tyrosine kinase crucial for relaying signals from the B cell antigen receptor (BCR) in cancerous B lymp...

Feb 26 2026 41853684
Replication of the Association between Retinal Aging Clock Susceptibility Genes and Retinal Age Gap in an Asian Population: The Nagahama Study.

PURPOSE: To replicate previously reported genetic associations for the retinal aging clock-quantified as the retinal age gap-in an East Asian populati...

Feb 26 2026 41958711
New treatments to rabies virus infections.

Rabies disease is the deadliest of all virus infections. Till now, vaccination is the most effective and reliable treatment for controlling rabies. Ho...

Feb 26 2026 41759787
Identifying Subgroups of People Living With HIV in British Columbia, Canada Based on Sexually Transmitted and Blood-Borne Infection Testing and Diagnostic Laboratory Data: A Retrospective Cohort Study.

BACKGROUND AND AIMS: Although combination antiretroviral therapy has decreased morbidity and mortality in people living with HIV (PLWH), the prevalenc...

Feb 26 2026 41767358
CXCL9 as a key feature for deep learning-based immune subtyping and prediction of immune checkpoint blockade response in triple-negative breast cancer.

BACKGROUND: Immune checkpoint blockade (ICB) therapy has provided a promising treatment option for patients with triple-negative breast cancer (TNBC)....

Feb 26 2026 41759266
Deep learning-assisted tumor radiomic dynamics on MRI predict pathological complete response in HCC undergoing immune-based therapy followed by hepatectomy.

BACKGROUND AIMS: Pathological complete response (pCR) following conversion therapy for initially unresectable hepatocellular carcinoma (uHCC) remains ...

Feb 26 2026 41746634
Population genomics reveals association of transposable elements variants with climatic adaptation in wild Amur grape.

Amur grape (Vitis amurensis Rupr.) is widely recognized for its cold tolerance traits and serves as a valuable genetic resource for breeding climate-r...

Feb 26 2026 41748614
PON-Del predictor for sequence retaining protein deletions.

Protein deletions are frequent among both disease-causing and tolerated variants. Several mechanisms at the DNA, RNA and protein levels can lead to de...

Feb 25 2026 41739875
INHBA: a mitochondrial-related pan-cell death gene associated with the prognosis and immunity of OSCC.

Oral squamous cell carcinoma (OSCC) is a malignant tumor characterized by both clinical and molecular heterogeneity. Its rising global incidence and m...

Feb 25 2026 41741523
Wheat yield prediction using integrated optical and radar remote sensing with machine learning across key phenological stages.

Precise and timely prediction of wheat yield is pivotal for ensuring global food security and optimizing agricultural management practices, particular...

Feb 25 2026 41741606
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