Infectious Disease

COVID-19

Latest AI and machine learning research in covid-19 for healthcare professionals.

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Flemboda artificial intelligence: hybrid fuzzy-convolutional neural network for efficient chromosome abnormality classification.

Chromosomal abnormality detection is a fundamental task in clinical genetics, as accurate identification of structural and numerical defects is essential for reliable diagnosis and treatment planning. However, many existing learning-based approaches failed to effectively capture diverse discriminative features, limiting their classification performance. To address this challenge, this study propos...

Jan 21 2026 41559480

Future risks of cyanobacterial blooms in lakes unveiled by open access data and integrated machine learning models.

Future projections of cyanobacterial blooms is of great significance for ecological risks management in lakes under the combined influences of human activities and climate change. However, due to the lack of long-term data on cyanobacterial blooms and the uncertainty of future prediction models, our current understanding of continental-scale cyanobacterial blooms is still insufficient. This study ...

Jan 20 2026 41579615
Personalized surveillance in giant congenital melanocytic nevus, including the role of AI, histopathology and MC1R genotyping: A case report.

Giant congenital melanocytic nevi (GCMN) are rare pigmented skin lesions present at birth that carry an increased risk of malignant melanoma and neuro...

Jan 20 2026 41624622
Pathomics Signature for Prognosis and CA19-9 Interception in Pancreatic Ductal Adenocarcinoma: A Real-Life, Multi-Center Study.

Histopathological hematoxylin and eosin (H&E) slides contain valuable prognostic information for pancreatic ductal adenocarcinoma (PDAC), yet systemat...

Jan 20 2026 41556438
Interpretable Artificial Intelligence in Assisting Treatment Response Prediction for Locally Advanced Rectal Cancer After Neoadjuvant Chemoradiotherapy: A Prospective, Multicenter, Human-Model Interaction Study.

PURPOSE: Preoperative assessment of pathologic complete response (pCR) to neoadjuvant therapy is an urgent need for anorectal preservation in patients...

Jan 20 2026 41556864
Translational and real-world evidence of trastuzumab biosimilar CT-P6 plus pertuzumab in neoadjuvant HER2-positive early breast cancer.

BACKGROUND: Data on neoadjuvant treatment with trastuzumab biosimilars, particularly CT-P6, in combination with pertuzumab, are limited. This study ev...

Jan 20 2026 41557021
Cross-Supervision Similarity Network for Medical Image Classification on Imbalanced Small Datasets.

Imbalanced small datasets are common scenarios in the field of machine learning for medical imaging, especially in real-world clinical applications. M...

Jan 20 2026 41557572
Classification of Alzheimer's Disease by Modeling Brain Networks as Signed Networks under Deep Learning Frameworks.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that remains a global challenge due to its complex pathology and the lack of defi...

Jan 19 2026 41553900
Fuzzy classification of sepsis subtypes and implications for trajectory and treatment.

BACKGROUND: Sepsis is common and deadly, and subtypes are proposed to guide precision treatment. However, little is known about the uncertainty in sub...

Jan 19 2026 41558249
Insights into the interplay between stroke and depression through lipid metabolism-related diagnostic genes.

Stroke, a result of acute cerebrovascular disease that causes cerebral dysfunction, often coexists with depression or even major depressive disorder (...

Jan 18 2026 41547864
OLink proteomic biomarker to predict clinical efficacy of Macaranga sinensis Müll.Arg: A nested case-control study.

ETHNOPHARMACOLOGICAL RELEVANCE: Despite the fact that herbal medicine has been used for a long time, their clinical application is challenged by uncle...

Jan 18 2026 41558579
Construction of musculoskeletal quantitative model based on deep learning and study of musculoskeletal relationship in patients with osteoporosis.

INTRODUCTION: Lumbar CT and MRI scans are helpful for osteoporosis (OP) screening. Deep learning enhances the efficiency and accuracy of musculoskelet...

Jan 18 2026 41558598
Boosting angiogenesis experimentally in ovo by biofunctionalizing collagen membranes with platelet-rich fibrin and hyaluronic acid: implications for regenerative oral surgery?

PURPOSE: Biocompatible collagen membranes (CM) are widely used in regenerative dentistry, particularly in guided tissue regeneration (GTR) and guided ...

Jan 17 2026 41546800
Machine Learning-Based Identification of Exosome-Associated Diagnostic Biomarkers in Acute Myocardial Infarction and in Silico Drug Prioritization.

BACKGROUND: Acute myocardial infarction (AMI) is a major global health burden, with current diagnostic biomarkers often limited by delayed elevation a...

Jan 17 2026 41546812
A novel hypothetical protein (SAUSA300_1684) confers excellent protection against multi-drug-resistant Staphylococcus aureus infection in the murine model.

Staphylococcus aureus is a leading cause of nosocomial infections, including sepsis, bacteraemia, pneumonia, and endocarditis, and continues to pose a...

Jan 17 2026 41548530
Predicting epistasis across proteins by structural logic.

Accurately predicting the phenotypic consequences of genetic variation is a major challenge for precision medicine. The problem is exacerbated by epis...

Jan 16 2026 41543897
AI-Assisted Multiplex SYBR Green I-Based qPCR for the Identification and Quantitative Analysis of Oral Microbiota.

Conventional multiplex qPCR faces challenges in quantitative multipathogen detection due to limited fluorescent channels, primer interference, and the...

Jan 16 2026 41544058
Alzheimer's disease prediction via an explainable CNN using genetic algorithm and SHAP values.

Convolutional neural networks (CNNs) are widely recognized for their high precision in image classification. Nevertheless, the lack of transparency in...

Jan 16 2026 41544026
Diagnostic Accuracy of the National Library of Medicine (NLM) Screener Application in Screening for Malaria Parasites Among Blood Donors at the Korle-Bu Blood Bank, Ghana: A Cross-Sectional Study.

BACKGROUND AND AIMS: Malaria is a deadly disease spread through the bite of an infected female Anopheles mosquito and remains the leading cause of mor...

Jan 16 2026 41550292
SyMetrics: an integrated machine learning model for evaluating the pathogenicity of synonymous variants in the human genome.

Synonymous single nucleotide variants (sSNVs), traditionally seen as neutral, are now recognized for their biological impact. To assess their relevanc...

Jan 15 2026 41551927
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