Critical Care

Latest AI and machine learning research in critical care for healthcare professionals.

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Subcategories: Sepsis
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Artificial intelligence for early diagnosis in emergency department.

In recent years, artificial intelligence (AI) has become an increasingly prominent player in emergency medicine, offering innovative tools to enhance the early diagnosis of acute conditions. This systematic review explores how AI, particularly through machine learning (ML) and deep learning (DL), is transforming the way physicians and healthcare professionals respond to high-stakes clinical scenar...

Jan 19 2026 41555414

Fuzzy classification of sepsis subtypes and implications for trajectory and treatment.

BACKGROUND: Sepsis is common and deadly, and subtypes are proposed to guide precision treatment. However, little is known about the uncertainty in subtype classification, and its implications for trajectory and treatment response. METHODS: In multiple electronic health record and trial data of adults with sepsis, we assigned patients clinical sepsis subtypes (α, β, γ, or δ-type), and measured unce...

Jan 19 2026 41558249
Clinician preferences for explainable AI in critical care: a comparative study of interpretable models and visualizations for intubation decision support.

BACKGROUND: The complexity of many AI models hinders their clinical adoption because the clinicians using them do not regard them as transparent. This...

Jan 18 2026 41570512
Interpretable machine learning model for predicting in-hospital mortality in elderly acute pancreatitis: Development and validation in a multicenter cohort.

BACKGROUND: Elderly acute pancreatitis (AP) patients face significantly higher in-hospital all-cause mortality, highlighting the need for effective ri...

Jan 18 2026 41570423
Clinical validation of a unified data-driven respiratory motion correction technique in 18F-FDG PET/CT imaging of upper abdominal lesions: a real-world study.

PURPOSE: Respiratory motion (RM)-related artifacts significantly impact image quality and diagnostic accuracy in PET/CT imaging. This study aimed to p...

Jan 18 2026 41547664
A novel hypothetical protein (SAUSA300_1684) confers excellent protection against multi-drug-resistant Staphylococcus aureus infection in the murine model.

Staphylococcus aureus is a leading cause of nosocomial infections, including sepsis, bacteraemia, pneumonia, and endocarditis, and continues to pose a...

Jan 17 2026 41548530
Gene Modification: Exploring the potential in treating kidney diseases.

Chronic kidney disease (CKD) is a leading cause of death worldwide. Currently available drugs slow but do not cure or prevent progression to end-stage...

Jan 17 2026 41554351
Development of a machine learning model to predict intensive care unit bed demand for adult elective surgical patients at a large United Kingdom National Health Service Trust.

BACKGROUND: Elective surgical admissions form a growing share of demand for ICU beds, a constrained resource. Capacity planning for these admissions i...

Jan 16 2026 41586383
Plasma glutamic acid predicts myelosuppression and mortality in septic patients using machine learning.

Myelosuppression is a common secondary manifestation of sepsis and is associated with increased morbidity and mortality. Recent evidence suggests that...

Jan 16 2026 41545523
DynaGraph: interpretable dynamic graph learning for temporal electronic health records.

Electronic health records (EHRs) capture evolving physiological processes, yet most machine learning models impose static or sequential assumptions th...

Jan 16 2026 41545647
A graph-based spatio-temporal framework for predicting safety-critical pedestrian-vehicle interactions at unsignalized crosswalks.

Pedestrian safety remains a critical global concern, especially in countries like India, where unsignalized crossings with limited traffic control con...

Jan 16 2026 41547101
Construction of a classification system for long-term care service needs among the elderly based on cluster analysis and machine learning: A multi-center, cross-sectional study in central China.

BACKGROUND: Rapid global aging has led to an increasing demand for long-term care services for the elderly; however, current long-term care systems ar...

Jan 15 2026 41619455
Prognostic Significance of Computed Tomography Severity Score for Machine Learning Prediction of Intensive Care Unit Admission in COVID-19 Patients.

OBJECTIVE: The computed tomography-severity score (CT-SS) quantifies the severity of pulmonary involvement and is significantly associated with diseas...

Jan 15 2026 41536171
A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications.

The immune defense function protecting the body from invasive pathogens is a key indicator of an individual's health and lacks of methods for quantita...

Jan 15 2026 41536212
Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches.

BACKGROUND: Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is ste...

Jan 15 2026 41540661
Machine learning frameworks for predicting pulmonary cell toxicities induced by metal ions in the atmosphere.

Metals in PM2.5 are closely associated with cardiopulmonary disease endpoints, potentially attributable to ionic species-induced oxidative stress effe...

Jan 15 2026 41547395
Multi-Task Cascade Forest Framework for Predicting Acute Toxicity across Species.

Evaluating chemical toxicity and its potential hazards to human health and the environment is essential in diverse fields, including medicine, industr...

Jan 15 2026 41551916
Robust multimodal mental workload classification: A cross-physiological condition machine learning approach.

BACKGROUND AND OBJECTIVE: Aircraft pilots can be faced with a high mental workload (MW) combined with moderate hypoxia and sleep restriction. We aimed...

Jan 14 2026 41576780
Multifeature Ultrasound-Based Classification for Breast Lesions: A Comparative Study of PONS Image Enhancement Technology.

OBJECTIVE: To overcome critical limitations of B-mode ultrasound in artificial intelligence diagnostics-including poor image quality and operator vari...

Jan 14 2026 41584234
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