Neurology

Dementia

Latest AI and machine learning research in dementia for healthcare professionals.

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Listening Beyond The Labels

Alzheimer’s Disease (AD), a progressive neurodegenerative condition of cognitive decline, presents f...

Integrating explainable AI with multiomics systems biology and EHR data mining for personalized drug repurposing in Alzheimer’s disease

Alzheimer’s disease (AD) is characterized by region- and patient-specific molecular heterogeneity, w...

Replacement of a single residue in an antibody completely abolishes cognate antigen binding, as predicted by theoretical methods

Structural insights into the interaction between antibodies and antigens at the atomic level are piv...

Uncertainty in Deep Learning for EEG under Dataset Shifts

As artificial intelligence (AI) is increasingly integrated into medical diagnostics, it is essential...

Comparative Analysis of Diffusion Models for Enhancing Alzheimer’s Disease Classification

Early and accurate detection of Alzheimer’s disease (AD) is vital for timely intervention and better...

Frequency bands EEG Biomarkers for Dementia using Graph Neural Networks

We introduce a simple and interpretable model for classification of electroencephalography (EEG) sig...

Neural Network-Enhanced Investigation of Ferroptosis and Druggability in Early-Onset Alzheimer’s Disease

Alzheimer’s disease (AD) is a complex neurodegenerative disorder which is multifactorial in nature. ...

ROSMAP-Compass: a data-harmonised, AI-ready atlas of 22 million single nuclei from the ROSMAP cohort

The Religious Orders Study and Memory and Aging Project (ROSMAP) cohort has generated the world’s mo...

An Explainable Web-Based Diagnostic System for Alzheimer’s Disease Using XRAI and Deep Learning on Brain MRI

Background Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive...

In Silico Design of APOE ɛ4 Interaction Inhibitor Peptides for Alzheimer’s Disease

Protein-protein interactions (PPIs) are essential for cellular functions, and their aberrant formati...

Alzheimer’s subtypes A supervised, unsupervised, multimodal, multilayered embedded recursive (SUMMER) AI study

Since Alzheimer’s disease (AD) is a heterogeneous disease, different subtypes may have distinct biol...

Graph-Based Modeling of Alzheimer’s Protein Interactions via Spiking Neural, Hyperdimensional Encoding, and Scalable Ray-Based Learning

This study introduces a novel computational framework for predicting protein-protein interactions (P...

An Open-Source Deep Learning-Based Toolbox for Automated Auditory Brainstem Response Analyses (ABRA)

Hearing loss is a pervasive global health challenge with profound impacts on communication, cognitiv...

AmyloDeep: pLM-based ensemble model for predicting amyloid propensity from the amino acid sequence

Amyloids are predominantly β-sheet-rich, stable protein structures that can maintain their presence ...

Disease-specific tau polymorphs define unique protein interaction networks across proteinopathies

Tau protein aggregates exhibit distinct conformations across tauopathies, but their disease-specific...

Frequency-Aware Interpretable Deep Learning Framework for Alzheimer’s Disease Classification Using rs-fMRI

Gaining insight into the spectral and temporal alterations in brain connectivity associated with Alz...

Evaluation of Deep Learning Algorithms to Predict Multiple Dementia-Related Neuropathologies from Brain MRI, Clinical and Genetic Data

Alzheimer’s disease and related dementias (ADRD) involve overlapping neurodegenerative and vascular ...

Hippocampal grey matter changes across scales in Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive and debilitating neurodegenerative disease of the central ...

Integrative Chemical Genetics Platform Identifies Condensate Modulators Linked to Neurological Disorders

Aberrant biomolecular condensates are implicated in multiple incurable neurological disorders, inclu...

Cross-species connectome comparisons reveal the network attributes of memory capacity and time series prediction

The brain’s connectome provides a powerful blueprint for designing efficient neural networks, yet th...

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