Neurology

Dementia

Latest AI and machine learning research in dementia for healthcare professionals.

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Detecting Cognitive Impairment and Psychological Well-being among Older Adults Using Facial, Acoustic, Linguistic, and Cardiovascular Patterns Derived from Remote Conversations

The aging society urgently requires scalable methods to monitor cognitive decline and identify social and psychological factors indicative of dementia risk in older adults. Our machine learning (ML) models captured facial, acoustic, linguistic, and cardiovascular features from 39 individuals with normal cognition or Mild Cognitive Impairment derived from remote video conversations and classified...

A comprehensive interpretable machine learning framework for Mild Cognitive Impairment and Alzheimer's disease diagnosis

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises volumetric measurements from brain MRI and genetic data from healthy individuals and patients with MCI/AD, obtained through the Alzheimer's Disease Neuroimaging ...

Not All Errors Are Equal: Investigation of Speech Recognition Errors in Alzheimer's Disease Detection

Automatic Speech Recognition (ASR) plays an important role in speech-based automatic detection of Alzheimer's disease (AD). However, recognition err...

Leveraging Prompt Learning and Pause Encoding for Alzheimer's Disease Detection

Compared to other clinical screening techniques, speech-and-language-based automated Alzheimer's disease (AD) detection methods are characterized by...

A Self-guided Multimodal Approach to Enhancing Graph Representation Learning for Alzheimer's Diseases

Graph neural networks (GNNs) are powerful machine learning models designed to handle irregularly structured data. However, their generic design ofte...

LVS-Net: A Lightweight Vessels Segmentation Network for Retinal Image Analysis

The analysis of retinal images for the diagnosis of various diseases is one of the emerging areas of research. Recently, the research direction has ...

Early Diagnosis of Alzheimer's Diseases and Dementia from MRI Images Using an Ensemble Deep Learning

Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timel...

Self-Supervised Masked Mesh Learning for Unsupervised Anomaly Detection on 3D Cortical Surfaces

Unsupervised anomaly detection in brain imaging is challenging. In this paper, we propose self-supervised masked mesh learning for unsupervised anom...

Graph-Based Biomarker Discovery and Interpretation for Alzheimer's Disease

Early diagnosis and discovery of therapeutic drug targets are crucial objectives for the effective management of Alzheimer's Disease (AD). Current a...

The Trusted Caregiver: The Influence of Eye and Mouth Design Incorporating the Baby Schema Effect in Virtual Humanoid Agents on Older Adults Users' Perception of Trustworthiness

The increasing proportion of the older adult population has made the smart home care industry one of the critical markets for virtual human-like age...

Genome-wide association neural networks identify genes linked to family history of Alzheimer's disease.

Augmenting traditional genome-wide association studies (GWAS) with advanced machine learning algorithms can allow the detection of novel signals in av...

Nov 22 2024 39775791
Explainable deep neural networks for predicting sample phenotypes from single-cell transcriptomics.

Recent advances in single-cell RNA-Sequencing (scRNA-Seq) technologies have revolutionized our ability to gather molecular insights into different phe...

Nov 22 2024 39814561
Introducing TEC-LncMir for prediction of lncRNA-miRNA interactions through deep learning of RNA sequences.

The interactions between long noncoding RNA (lncRNA) and microRNA (miRNA) play critical roles in life processes, highlighting the necessity to enhance...

Nov 22 2024 39927859
Efficient Brain Imaging Analysis for Alzheimer's and Dementia Detection Using Convolution-Derivative Operations

Alzheimer's disease (AD) is characterized by progressive neurodegeneration and results in detrimental structural changes in human brains. Detecting ...

Deep learning assisted quantitative analysis of Aβ and microglia in patients with idiopathic normal pressure hydrocephalus in relation to cognitive outcome.

Neuropathologic changes of Alzheimer disease (AD) including Aβ accumulation and neuroinflammation are frequently observed in the cerebral cortex of pa...

Nov 1 2024 39101555
Comparing machine learning and deep learning models to predict cognition progression in Parkinson's disease.

Cognitive decline in Parkinson's disease (PD) varies widely. While models to predict cognitive progression exist, comparing traditional probabilistic ...

Nov 1 2024 39513668
Generative forecasting of brain activity enhances Alzheimer's classification and interpretation

Understanding the relationship between cognition and intrinsic brain activity through purely data-driven approaches remains a significant challenge ...

Exploiting Longitudinal Speech Sessions via Voice Assistant Systems for Early Detection of Cognitive Decline

Mild Cognitive Impairment (MCI) is an early stage of Alzheimer's disease (AD), a form of neurodegenerative disorder. Early identification of MCI is ...

Copula-Linked Parallel ICA: A Method for Coupling Structural and Functional MRI brain Networks

Different brain imaging modalities offer unique insights into brain function and structure. Combining them enhances our understanding of neural mech...

SGUQ: Staged Graph Convolution Neural Network for Alzheimer's Disease Diagnosis using Multi-Omics Data

Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the leading cause of dementia, significantly impacting cost, mortality, and bur...

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