Neurology

Dementia

Latest AI and machine learning research in dementia for healthcare professionals.

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Deep learning-based identification of genetic variants: application to Alzheimer's disease classification.

Deep learning is a promising tool that uses nonlinear transformations to extract features from high-dimensional data. Deep learning is challenging in genome-wide association studies (GWAS) with high-dimensional genomic data. Here we propose a novel three-step approach (SWAT-CNN) for identification of genetic variants using deep learning to identify phenotype-related single nucleotide polymorphisms...

Mar 10 2022 35183061

Differential Role for Hippocampal Subfields in Alzheimer's Disease Progression Revealed with Deep Learning.

Mild cognitive impairment (MCI) is often considered the precursor of Alzheimer's disease. However, MCI is associated with substantially variable progression rates, which are not well understood. Attempts to identify the mechanisms that underlie MCI progression have often focused on the hippocampus but have mostly overlooked its intricate structure and subdivisions. Here, we utilized deep learning ...

Jan 22 2022 34322704
Advances in Deep Neuropathological Phenotyping of Alzheimer Disease: Past, Present, and Future.

Alzheimer disease (AD) is a neurodegenerative disorder characterized pathologically by the presence of neurofibrillary tangles and amyloid beta (Aβ) p...

Jan 21 2022 34981115
The Use of Robotics in Dementia Care: An Ethical Perspective.

Dementia and other related diseases are becoming increasingly diagnosed and are placing a serious strain on the healthcare system. Robotic technology ...

Jan 14 2022 35062167
Identifying Mild Cognitive Impairment by Using Human-Robot Interactions.

BACKGROUND: Mild cognitive impairment (MCI), which is common in older adults, is a risk factor for dementia. Rapidly growing health care demand associ...

Jan 1 2022 34897086
Utility of Machine Learning Approach with Neuropsychological Tests in Predicting Functional Impairment of Alzheimer's Disease.

BACKGROUND: In assessing the levels of clinical impairment in dementia, a summary index of neuropsychological batteries has been widely used in descri...

Jan 1 2022 34924390
Chronic Beneficial Effect of Makeup Therapy on Cognitive Function of Dementia and Facial Appearance Analyzed by Artificial Intelligence Software.

BACKGROUND: Makeup greatly impacts normal social lives but can also be a non-pharmacological form of therapy for dementia.

Jan 1 2022 34924394
A Machine Learning-Based Holistic Approach to Predict the Clinical Course of Patients within the Alzheimer's Disease Spectrum.

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative condition driven by multifactorial etiology. Mild cognitive impairment (MCI) is a transiti...

Jan 1 2022 34958014
The Use of Machine Learning in MicroRNA Diagnostics: Current Perspectives.

MicroRNAs constitute small non-coding RNAs that play a pivotal role in regulating the translation and degradation of mRNA and have been associated wit...

Jan 1 2022 35984026
Effects of Exercise-Diet Therapy on Cognitive Function in Healthy Elderly People Evaluated by Deep Learning Based on Basic Blood Test Data.

BACKGROUND: Recent studies reported that vascular cognitive impairment in the elderly caused by arteriosclerosis plays an important role in cognitive ...

Jan 1 2022 36527628
Applications and Challenges of Machine Learning Methods in Alzheimer's Disease Multi-Source Data Analysis.

BACKGROUND: Recent development in neuroimaging and genetic testing technologies have made it possible to measure pathological features associated with...

Dec 31 2021 35386189
Educational Program Using Robots for Preventing Cognitive Decline of Elderly Persons.

An expected surge of dementia patients in Japan indicates a pressing need to establish countermeasures. As described herein, by developing an educatio...

Dec 15 2021 34920577
Interpretable temporal graph neural network for prognostic prediction of Alzheimer's disease using longitudinal neuroimaging data.

Alzheimer's disease (AD) is a progressive neurodegenerative brain disorder characterized by memory loss and cognitive decline. Early detection and acc...

Dec 1 2021 35299717
[Retinal Imaging as Potential Biomarkers for Dementia].

Alzheimer's disease (AD) is a leading cause of dementia, and the current diagnostic methods of AD, such as positron emission tomography imaging, have ...

Nov 1 2021 34759057
Deep Learning on SDF for Classifying Brain Biomarkers.

Biomarkers are one of the primary medical signs to facilitate the early detection of Alzheimer's disease. The small beta-amyloid (Aβ) peptide is an im...

Nov 1 2021 34891469
Early Detection of Low Cognitive Scores from Dual-task Performance Data Using a Spatio-temporal Graph Convolutional Neural Network.

Detecting low cognitive scores at an early stage is important for delaying the progress of dementia. Investigations of early-stage detection have empl...

Nov 1 2021 34891657
A comparative study of AI systems for epileptic seizure recognition based on EEG or ECG.

The majority of studies for automatic epileptic seizure (ictal) detection are based on electroencephalogram (EEG) data, but electrocardiogram (ECG) pr...

Nov 1 2021 34891722
Federated Learning via Conditional Mutual Learning for Alzheimer's Disease Classification on T1w MRI.

Data-driven deep learning has been considered a promising method for building powerful models for medical data, which often requires a large amount of...

Nov 1 2021 34891771
Data-Limited Deep Learning Methods for Mild Cognitive Impairment Classification in Alzheimer's Disease Patients.

Mild Cognitive Impairment (MCI) is the stage between the declining of normal brain function and the more serious decline of dementia. Alzheimer's dise...

Nov 1 2021 34891795
Input Agnostic Deep Learning for Alzheimer's Disease Classification Using Multimodal MRI Images.

Alzheimer's disease (AD) is a progressive brain disorder that causes memory and functional impairments. The advances in machine learning and publicly ...

Nov 1 2021 34891847
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