Psychiatry

Depression

Latest AI and machine learning research in depression for healthcare professionals.

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Showing 521-540 of 2,048 articles

Explainable machine learning for mental health prediction from social media behavior: a nested cross-validation study with SHAP and LIME interpretability.

Social media behavior is a promising source of early indicators for psychological distress; however, predictive models often lack transparency, limiting their adoption in mental health settings. This paper describes an explainable machine learning framework for predicting self-reported depression risk based on behavioral features collected from 481 anonymized social media users. Three supervised l...

Jan 22 2026 41569469

Syntactic complexity of written text as a structural linguistic marker of depressive symptoms.

BACKGROUND: Language analysis methods have been increasingly explored for the detection of depressive symptoms. However, current approaches have largely focused on analysing the thematic content of language, while the underlying structure and grammatical composition of language remains underexamined. The current study assessed features of syntactic complexity in written text as potential linguisti...

Jan 21 2026 41577043
Psychiatric Documentation and Management in Primary Care With Artificial Intelligence Scribe Use.

IMPORTANCE: Despite increasingly widespread use of artificial intelligence (AI)-driven ambient scribes in medicine, the extent to which they are assoc...

Jan 21 2026 41563771
Leveraging an AI-Driven Voice Companion to Enhance Mental Health in Older Adults in Post-Acute and Long-Term Care Settings: A Feasibility Study.

Loneliness, depression, and anxiety are prevalent among older adults in post-acute and long-term care settings and are associated with adverse health ...

Jan 20 2026 41461198
Microbiota-metabolome interplay in depression: Metabolic insights and diagnostic potential.

Mounting evidence highlights the interplay between gut microbiota, metabolism, and depression. In this study, we analyze fecal and serum metabolomes i...

Jan 20 2026 41564867
Autonomous conversational agents for loneliness, social isolation, depression, and anxiety in older people without cognitive impairment: Systematic review and meta-analysis.

Loneliness is a major psychological challenge in older adulthood, contributing to increased risks of depression, anxiety, and mortality. Conversationa...

Jan 20 2026 41556104
Lateralized effects of vagus nerve stimulation on cortical spreading depression: insights from a mouse model.

OBJECTIVES: Vagus nerve stimulation (VNS) is increasingly recognized as a therapeutic approach for neurological disorders, such as epilepsy, migraine,...

Jan 20 2026 41557703
A study on the coupling mechanism between the urban environment and depression perception based on deep learning and street view image.

With the accelerated urbanization process, the impact of the urban environment on the mental health of residents has attracted extensive attention. Ho...

Jan 20 2026 41559177
Interface-engineered Gd₂O₃/ZrO₂ bilayer memristor for emulating synaptic plasticity in neuromorphic systems.

Rare-earth-based materials are attracting growing interest for neuromorphic devices due to their unique electronic structures, defect engineering capa...

Jan 19 2026 41579574
GIN-transformer based pairwise graph contrastive learning framework.

Resting-state functional magnetic resonance imaging (rs-fMRI) provides critical biomarkers for diagnosing neuropsychiatric disorders such as autism sp...

Jan 18 2026 41576557
Insights into the interplay between stroke and depression through lipid metabolism-related diagnostic genes.

Stroke, a result of acute cerebrovascular disease that causes cerebral dysfunction, often coexists with depression or even major depressive disorder (...

Jan 18 2026 41547864
Transfer learning from 2D natural images to 4D fMRI brain images via geometric mapping.

Functional magnetic resonance imaging (fMRI) allows real-time observation of brain activity through blood oxygen level-dependent (BOLD) signals and is...

Jan 17 2026 41576824
Association of depressive symptoms with systemic immune-inflammation index and platelet parameters among survivors of myocardial infarction: a cross-sectional NHANES study enhanced by machine learning and SHAP analysis.

BACKGROUND: Inflammation is implicated in the elevated risk of depressive disorder following myocardial infarction (MI), with platelets serving as a k...

Jan 17 2026 41547726
A Study on the Effectiveness of Al-Assisted Patient Health Education Using Voice Cloning and ChatGPT: A Prospective Randomized Controlled Trial.

BACKGROUND: Traditional patient education often lacks personalization and engagement, potentially limiting knowledge acquisition and treatment adheren...

Jan 17 2026 41548948
Deep learning for depression prediction in older adults: A retrospective cohort study from CHARLS (2011-2020) with independent cohort validation in CLHLS (2008-2018).

BACKGROUND: Geriatric depression is highly prevalent yet under-recognized, severely affecting older adults' quality of life and social functioning. Th...

Jan 17 2026 41554486
Data Science Education for Residents, Researchers, and Students in Psychiatry and Psychology: Program Development and Evaluation Study.

BACKGROUND: The use of artificial intelligence (AI) to analyze health care data has become common in behavioral health sciences. However, the lack of ...

Jan 16 2026 41544003
Deep learning for detecting depression in individuals with and without alexithymia.

BACKGROUND: To accurately detect individuals' mental health issues using artificial intelligence and self-report scales, it is crucial to recognize ho...

Jan 16 2026 41545479
Machine learning guided structural dynamics identifies translation elongation factor 1 (EEF1A1) as an immunological biomarker and marine natural products as therapeutic leads for rheumatoid arthritis with major depressive disorder.

Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects synovial joints, especially those of the hands, elbows, wrists, ...

Jan 16 2026 41547049
Exploration of Mental Health and Stress Among Nursing Interns Through a Chatbot: A Single-Group Pilot Study.

BACKGROUND: Nursing interns face early clinical distress; chatbot-based mental health tools show promise, although evidence of their feasibility and e...

Jan 15 2026 41533862
Increasing engagement with cognitive-behavioral therapy (CBT) using generative AI: a randomized controlled trial (RCT).

BACKGROUND: Shortages in mental healthcare lead to long periods of inadequate support for many patients. While digital interventions offer a scalable ...

Jan 15 2026 41540194
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