Latest AI and machine learning research in dermatology for healthcare professionals.
External cervical resorption (ECR) is a resorptive process affecting teeth. While in some patients, active resorption ceases and gets replaced by osseous tissue, in other cases, the resorption progresses and ultimately results in tooth loss. For proper ECR assessment, cone-beam computed tomography (CBCT) is the recommended imaging modality, enabling a 3-D characterization of these lesions. While...
Chronic itch affects 13% of the US population, is highly debilitating, and underlies many medical conditions. A major challenge in clinical care and new therapeutics development is the lack of an objective measure for quantifying itch, leading to reliance on subjective measures like patients' self-assessment of itch severity. In this paper, we show that a home radio device paired with artificial...
Denoising Diffusion Models (DDMs) are widely used for high-quality image generation and medical image segmentation but often rely on Unet-based arch...
Multiplex immunofluorescence (mIF) imaging plays a crucial role in studying multiple biomarkers and their interactions within the tumour microenvironm...
Tissue microenvironments reprogram local cellular states in disease, yet current computational spatial methods remain descriptive and do not simulate ...
A robust artificial intelligence-assisted workflow for tumor assessment in pathology requires not only accurate classification but also precise lesion...
Atopic dermatitis (AD) is a chronic inflammatory skin disease driven by complex interactions among genetic, environmental, and microbial factors; howe...
Despite increased understanding of psoriasis pathogenesis, molecular classification of clinical phenotypes and disease severity is poorly defined. Kno...
Cetaceans (whales and dolphins) are important ecosystem sentinels but face growing threats from major disease-related mortality events expected to int...
Large language models are increasingly being used by dermatology professionals to support diagnostic investigation, patient education, and medical res...
Itch or pruritus invokes a specific reflexive and repetitive directed nocifensive behavioural response, known as scratching. Recent decades have revea...
Elucidating drug response mechanisms in human melanoma is crucial for improving treatment outcomes. Although scRNA-seq captures gene expression at the...
Neurological disorders often originate from progressive brain network dysfunctions that start years before symptoms appear. How these changes emerge i...
Analyzing whole tissue architecture remains challenging due to the inherent complexity of multicellular organization, variable morphology, and the lim...
Linking spatial transcriptomic data to clinically relevant phenotypes is essential for advancing spatially informed precision oncology. Here, we prese...
Malassezia pachydermatis is a zoophilic yeast found on the skin and in the outer ear canal of many mammals. It normally maintains a commensal lifestyl...
Biological systems can be interrogated by perturbing individual components and observing the consequences across molecular, cellular, and phenotypic l...
Here we are introducing CryoPhold, a modular workflow that unifies AlphaFold-based ensemble generation, Bayesian reweighting against experimental cryo...
In cell biology, optical techniques are increasingly used to measure cells’ internal states (biosensors) and to stimulate cellular responses (optogene...
Brain metastasis (BrM) is a serious complication of advanced cancers and remains difficult to predict before clinical symptoms appear. To investigate ...