Devices and Vaccines

Skilled reaching tasks for head-fixed mice using a robotic manipulandum.

Skilled forelimb behaviors are among the most important for studying motor learning in multiple species including humans. This protocol describes learned forelimb tasks for mice using a two-axis robotic manipulandum. Our device provides a highly compact adaptation of actuated planar two-axis arms that is simple and inexpensive to construct. This paradigm has been dominant for decades in primate mo...

Automatic detection of brachytherapy seeds in 3D ultrasound images using a convolutional neural network.

A novel approach for automatic localization of brachytherapy seeds in 3D transrectal ultrasound (TRUS) images, using machine learning based algorithm, is presented. 3D radiofrequency ultrasound signals were collected from 13 patients using the linear array of the TRUS probe during the brachytherapy procedure in which needles are used for insertion of stranded seeds. Gold standard for the location ...

Learning metal artifact reduction in cardiac CT images with moving pacemakers.

Metal objects in the human heart such as implanted pacemakers frequently lead to heavy artifacts in reconstructed CT image volumes. Due to cardiac mot...

How to manage a partial detachment of the ureter during robotic radical prostatectomy?

The management of a ureteral orifice injury occurring during robotic radical prostatectomy (RARP) represents a challenge for urologists. Several techn...

First-in-human evaluation of a hand-held automated venipuncture device for rapid venous blood draws.

Obtaining venous access for blood sampling or intravenous (IV) fluid delivery is an essential first step in patient care. However, success rates rely ...

Portable Detection of Apnea and Hypopnea Events Using Bio-Impedance of the Chest and Deep Learning.

Sleep apnea is one of the most common sleep-related breathing disorders. It is diagnosed through an overnight sleep study in a specialized sleep clini...

Prediction of peptide binding to MHC using machine learning with sequence and structure-based feature sets.

Selecting peptides that bind strongly to the major histocompatibility complex (MHC) for inclusion in a vaccine has therapeutic potential for infection...

Gate-Tunable Synaptic Dynamics of Ferroelectric-Coupled Carbon-Nanotube Transistors.

Artificial neural networks (ANNs) based on synaptic devices, which can simultaneously perform processing and storage of data, have superior computing ...

Strain-controlled power devices as inspired by human reflex.

Bioinspired electronics are rapidly promoting advances in artificial intelligence. Emerging AI applications, e.g., autopilot and robotics, increasingl...

Evaluating Convolutional Neural Networks for Cage-Free Floor Egg Detection.

The manual collection of eggs laid on the floor (or 'floor eggs') in cage-free (CF) laying hen housing is strenuous and time-consuming. Using robots f...

pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens.

Identification of neoantigens is a critical step in predicting response to checkpoint blockade therapy and design of personalized cancer vaccines. Thi...

Automated tracheal intubation in an airway manikin using a robotic endoscope: a proof of concept study.

Robotic endoscope-automated via laryngeal imaging for tracheal intubation (REALITI) has been developed to enable automated tracheal intubation. This p...

Fully automatic estimation of pelvic sagittal inclination from anterior-posterior radiography image using deep learning framework.

BACKGROUND AND OBJECTIVE: Malposition of the acetabular component causes dislocation and prosthetic impingement after Total Hip Arthroplasty (THA), wh...

Machine learning-based identification of hip arthroplasty designs.

BACKGROUND: The purposes of this study were to develop a machine learning-based implant recognition program and to verify its accuracy.

Ratiometric fluorescent sensing system for drug residue analysis: Highly sensitive immunosensor using dual-emission quantum dots hybrid and compact smartphone based-device.

Immunoassays such as the enzyme-linked immunosorbent assay (ELISA) are utilized extensively for detecting protein biomarkers and small molecules in he...

Effect of experimental infectious bursal disease virus on clinical signs and pathogenesis of avian influenza virus HN in turkey by real time PCR.

Infectious bursal disease virus (IBDV) in turkeys may result in immunosuppression, and inability of turkeys to resist nonpathogenic or less pathogenic...

ISFET and Dex-AgNPs based portable sensor for reusable and real-time determinations of concanavalin A and glucose on smartphone.

In this paper, a portable real-time sensing device was built for Concanavalin A (Con A) and glucose detection using a smartphone. The ion-sensitive fi...

CT based measurement of anatomical dimensions of femur and its relevance in nail designs for proximal femoral fractures.

INTRODUCTION: The purpose of this study was to obtain computed tomography (CT) based measurements of femoral dimensions in adults, to identify its rel...

Therapeutic Anticoagulation With an Ultra-Low Concentration Argatroban-Based Purge Solution for Percutaneous Ventricular Assist Device in Patient With Heparin-Induced Thrombocytopenia.

Percutaneous left ventricular assist devices (pVADs) require a continuous purge solution containing heparin to prevent pump thrombosis and device fai...

Immunogenicity and safety of a 12-valent pneumococcal conjugate vaccine in infants aged 6-10 weeks: a randomized double-blind active-controlled trial.

BACKGROUND: Pneumococcal diseases among children aged <5 years worldwide are associated with high annual mortality rates.