Endocrinology

[Leptin sexual dimorphism, insulin resistance, and body composition in normal weight prepubescent].

INTRODUCTION: The prepubertal stage is a critical period of body fat development, in which leptin and insulin re sistance has been associated, however, there are few studies in normal-weight prepubescents. Ob jective: To assess the relationship between leptin and body composition and insulin resistance in a group of normal-weight prepubescents.

Comparison of Machine Learning Models for the Androgen Receptor.

The androgen receptor (AR) is a target of interest for endocrine disruption research, as altered signaling can affect normal reproductive and neurological development for generations. In an effort to prioritize compounds with alternative methodologies, the U.S. Environmental Protection Agency (EPA) used data from 11 assays to construct models of AR agonist and antagonist signaling pathways. While...

Machine Learning Algorithms for the Prediction of Central Lymph Node Metastasis in Patients With Papillary Thyroid Cancer.

BACKGROUND: Central lymph node metastasis (CLNM) occurs frequently in patients with papillary thyroid cancer (PTC), but performing prophylactic centra...

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BACKGROUND: Currently there is an ever increasing interest in Lu-177 targeted radionuclide therapies, which target neuro-endocrine and prostate tumour...

Defining and Classifying New Subgroups of Diabetes.

An etiologically based classification of diabetes is needed to account for the heterogeneity of type 1 and type 2 diabetes (T1D and T2D) and emerging ...

Fourier transform infrared spectroscopy combined with deep learning and data enhancement for quick diagnosis of abnormal thyroid function.

BACKGROUND: To evaluate the Fourier transform infrared spectroscopy (FT-IR) combined with deep learning models to allow for quick diagnosis of abnorma...

Multi-Hour Blood Glucose Prediction in Type 1 Diabetes: A Patient-Specific Approach Using Shallow Neural Network Models.

Considering current insulin action profiles and the nature of glycemic responses to insulin, there is an acute need for longer term, accurate, blood ...

Resection of the medial wall of the cavernous sinus in functioning pituitary adenomas: Technical note and outcomes in a matched-cohort study.

BACKGROUND: Parasellar dural invasion can be associated with treatment failure after excision of functioning pituitary adenomas. Because the medial wa...

Calcitonin Levels in Thyroid Disease Are Not Affected by Autoimmune Thyroiditis or Differentiated Thyroid Carcinoma.

INTRODUCTION: Association between hypercalcitoninemia and pathological conditions such as autoimmune thyroiditis (AIT) or differentiated thyroid carci...

Application of Computed Tomography Imaging in Diagnosis of Endocrine Nerve of Gastric Cancer and Nursing Intervention Effect.

In this article, some parameters and characteristics of computed tomography (CT) images in patients with gastric cancer are analyzed and the applicati...

Low Testosterone on Social Media: Application of Natural Language Processing to Understand Patients' Perceptions of Hypogonadism and Its Treatment.

BACKGROUND: Despite the results of the Testosterone Trials, physicians remain uncomfortable treating men with hypogonadism. Discouraged, men increasin...

Machine learning in predicting early remission in patients after surgical treatment of acromegaly: a multicenter study.

PURPOSE: Accurate prediction of postoperative remission is beneficial for effective patient-physician communication in acromegalic patients. This stud...

Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes.

Early and precise identification of individuals with prediabetes and type 2 diabetes (T2D) at risk for progressing to chronic kidney disease (CKD) is ...

Important Tools for Use by Pediatric Endocrinologists in the Assessment of Short Stature.

Assessment and management of children with growth failure has improved greatly over recent years. However, there remains a strong potential for furthe...

Prediction of Type II Diabetes Onset with Computed Tomography and Electronic Medical Records.

Type II diabetes mellitus (T2DM) is a significant public health concern with multiple known risk factors (, body mass index (BMI), body fat distributi...

Cardiac Troponin Is Elevated in Patients with Thyrotoxicosis and Decreases as Thyroid Function Improves and Brain Natriuretic Peptide Levels Decrease.

INTRODUCTION: High-sensitive cardiac troponin reflects micro-myocardial injury in the absence of overt myocardial infarction.

THEIA™ development, and testing of artificial intelligence-based primary triage of diabetic retinopathy screening images in New Zealand.

AIM: To develop and evaluate an artificial intelligence triage system with high sensitivity for detecting referable diabetic retinopathy and maculopat...

Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms.

Environmental toxicants affect human health in various ways. Of the thousands of chemicals present in the environment, those with adverse effects on t...

Identification of Potential Type II Diabetes in a Large-Scale Chinese Population Using a Systematic Machine Learning Framework.

BACKGROUND: An estimated 425 million people globally have diabetes, accounting for 12% of the world's health expenditures, and the number continues to...

Successful Treatment of Allergic Bronchopulmonary Aspergillosis Using a Combination of Inhaled Fluticasone Furoate/Vilanterol and Oral Voriconazole.

Systemic corticosteroids are considered to be the standard treatment for allergic bronchopulmonary aspergillosis (ABPA). However, there is controversy...