Endocrinology

Latest AI and machine learning research in endocrinology for healthcare professionals.

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TLR3 as a PANoptosis-related gene: a potential diagnostic biomarker and therapeutic target for diabetic retinopathy.

UNLABELLED: WGCNA was used to identify DR-related PANoptosis genes, and the LASSO, SVM-RFE, and Random Forest machine learning models were then employed to identify key PANoptosis-related genes. The lncRNA-miRNA-TLR3 networks were constructed, and the levels of hub lncRNAs, hub miRNAs and TLR3 were measured in a high-glucose cell model. The luciferase reporter assay was employed to validate the in...

Mar 10 2026 41821661

A multimodal retinal image dataset for diabetic retinopathy detection using foundation models.

Diabetic Retinopathy (DR), a leading cause of preventable blindness worldwide, underscores the urgent need for robust AI-driven diagnostic tools. Although various deep learning models for retinal imaging have emerged, their evaluation remains constrained by limited public available datasets that lack both large-scale coverage and fine-grained annotations, compromising reliable assessments of model...

Mar 10 2026 41807442
Machine learning-based identification of abnormal functional connectivity in obesity across different metabolic states.

BACKGROUND: Obesity is a major health concern linked to chronic conditions such as diabetes and cardiovascular disease. However, most neurological stu...

Mar 10 2026 41807824
A targeted proteomics assay for the preoperative diagnosis of thyroid nodules.

Accurate preoperative diagnosis of thyroid nodules via fine-needle aspiration (FNA) biopsy remains challenging, particularly in cases with indetermina...

Mar 10 2026 41812663
Molecular-level understanding of the aging bone and regeneration mechanisms using computational methods.

Bone degeneration diseases, such as osteoporosis, are skeletal disorders characterized by diminished bone mass and increased susceptibility to fractur...

Mar 10 2026 41805841
[Digital transformation in endocrinology/diabetology, pneumology, and hematology/oncology : Where do we stand today-and what lies ahead?].

As in many areas of medicine, increasing digitalisation is also having an impact on everyday practice in internal medicine, entailing both enormous po...

Mar 10 2026 41806053
Evaluating Large Language Models-Generated Health Education Materials for Discharged Patients with Diabetes: A Comparative Analysis.

BACKGROUND: Diabetes is a chronic condition requiring long-term management, and continuous health education is vital for improving disease awareness a...

Mar 10 2026 41807129
Hybrid Aquila optimizer-Harris Hawks optimization for CNN hyperparameter tuning in brain tumor classification.

Magnetic resonance imaging (MRI) is hard to categorize properly in terms of interclass similarity, there is data imbalance, and sensitive clinical dec...

Mar 9 2026 41803423
Comprehensive evaluation of triglyceride glucose index-a body shape index (TyG-ABSI) for incident peripheral artery disease: data-driven phenotyping and machine learning-based risk prediction in the UK Biobank.

BACKGROUND: The prevalence of Peripheral Artery Disease (PAD) is rising globally, yet early risk stratification remains challenging due to the limitat...

Mar 9 2026 41803825
Identifying Predictors of Early Treatment Intensification in Individuals With Type 2 Diabetes Treated With GLP-1 Receptor Agonists: A Machine Learning-Based Analysis of a Large Real World Cohort.

AIMS: Despite the proven efficacy of GLP-1 receptor agonists (GLP-1 RAs), many patients with type 2 diabetes (T2DM) are not able to achieve glycaemic ...

Mar 9 2026 41804217
Training and validation of an automated algorithm to differentiate no and minimal diabetic retinopathy from more severe stages in wide-field images.

PURPOSE: Diabetic retinopathy (DR) is a leading cause of blindness in the working-age population. Screening is essential to identify and treat sight-t...

Mar 9 2026 41800557
LRF-UNet: Low-Rank Factorized Convolution Deep-Learning Networks for Visceral Adipose and Muscle Tissue Segmentation in Abdominal Computed Tomography Image.

Quantitative analysis of skeletal muscle (SM) and visceral adipose tissue (VAT) cross-sectional volumes at the third lumbar vertebral level (L3) on ab...

Mar 9 2026 41801305
AI-Enabled Personalization of Semaglutide Therapy in Type 2 Diabetes: Systematic Review With an Integration Framework.

BACKGROUND: Type 2 diabetes mellitus (T2D) is a rapidly growing global health concern requiring innovative treatment methods. Ozempic (semaglutide), a...

Mar 9 2026 41802231
An Accurate Glucose Detection Platform Using Colorimetry and Supervised Learning Algorithms.

Maintaining optimal health and preventing diabetes-related complications require accurate and timely monitoring of blood glucose levels. In this conte...

Mar 9 2026 41802365
BigEye: a clinically interpretable deep learning framework for diabetic retinopathy detection and stage prediction.

Diabetic Retinopathy (DR) is a major cause of vision loss and blindness in diabetic individuals. DR is conventionally diagnosed by assessing retinal l...

Mar 8 2026 41796249
AI-Driven Diagnostics vs. Clinician Assessment in Diabetic Retinopathy: A Comparative Analysis at a Secondary Eye Care Centre.

PURPOSE: To determine the diagnostic accuracy and reliability of artificial intelligence (AI) in identifying diabetic retinopathy (DR) and macular oed...

Mar 8 2026 41797256
Artificial Intelligence in Screening and Grading Diabetic Eye Diseases: A Systematic Review From Algorithms to Clinic.

SIGNIFICANCE: This systematic review comprehensively synthesises the progress of artificial intelligence in the grading diagnosis of diabetes-related ...

Mar 8 2026 41796091
Characterization of biomarker profiles in patients with coronary artery disease: A prospective coronary computed tomography angiography study.

BACKGROUND AND AIMS: Conventional biomarkers such as low-density lipoprotein (LDL) and high-density lipoprotein may fail to identify patients' risk fo...

Mar 7 2026 41802525
Integrating the Glycemia Risk Index Into Clinical Practice and Research: A Consensus Report.

A panel of experts in the use of continuous glucose monitoring (CGM) data in the treatment of diabetes met in Burlingame, California on October 27, 20...

Mar 7 2026 41793701
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