Latest AI and machine learning research in endocrinology for healthcare professionals.
BACKGROUND: Accurate preoperative evaluation of cT1N0M0 papillary thyroid carcinoma (PTC) is essential for guiding appropriate treatment strategies. Although ultrasound is widely used for clinical staging, it has limitations in detecting lymph node metastasis (LNM) and capsular invasion (CI), which may lead to misclassification of high-risk patients. Such undetected risks pose safety concerns for ...
The pathogenesis of diabetic cardiomyopathy (DCM) remains incompletely understood. The present study employed weighted gene co‑expression network analysis to analyze the DCM transcriptome dataset from the Gene Expression Omnibus (GEO) database to identify genes associated with this disease. Subsequently, both internal and external validation of the expression of the characterized genes was perform...
The automatic screening of thyroid nodules using computer-aided diagnosis holds great promise in reducing missed and misdiagnosed cases in clinical pr...
Breast cancer is the leading cause of cancer-related mortality among women worldwide. The development of predictive biomarkers and immunologic markers...
Prediabetes represents an early stage of glucose metabolism disorder with significant public health implications. Although traditional lifestyle inter...
PURPOSE: To evaluate and quantify diabetes-related retinal and choroid perfusion changes in individuals with and without high myopia and explore their...
The pain-free monitoring of blood-based biomarkers is essential for early detection of diseases like cancers, infections, and metabolic disorders such...
Highly sensitive detection and in situ tracing analysis of small-molecule biomarkers are particularly indispensable to deciphering the pathogenesis an...
The association between obesity and cancer risk carries substantial public health ramifications as obesity promotes cancer advancement via many cellul...
Glioma is a highly malignant brain tumor with limited treatment options. We employed the Computational Analysis of Novel Drug Opportunities (CANDO) pl...
Long COVID can develop in individuals who have had COVID-19, regardless of the severity of their initial infection or the treatment they received. Se...
BACKGROUND: This study investigated the cost-effectiveness and clinical impact of the 3E model (education, empowerment, and economy) in diabetes manag...
Over the past few decades, the rising burden of metabolic disease, including type 2 diabetes, prediabetes, obesity, and metabolic dysfunction-associat...
Aging processes underlie common chronic cardiometabolic diseases such as heart failure and diabetes. Cross-organ/tissue interactions can accelerate ag...
α-Glucosidase is a key enzyme responsible for controlling the blood glucose, making a pivotal target in the treatment of type 2 diabetes mellitus. Pre...
BACKGROUND: Cytopathology cannot be used to reliably distinguish follicular thyroid adenoma (FTA) from follicular thyroid carcinoma (FTC), the second ...
RATIONALE AND OBJECTIVES: Our objective is to develop and validate a deep learning radiomics nomogram (DLRN) based on preoperative ultrasound images a...
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) has been shown to play an important role in the treatment of impaired glucose tolerance, insulin re...
Decreased glucose tolerance is recognized as a factor associated with Parkinson's disease (PD) progression, yet the relationship between HbA1c and PD ...
BACKGROUND: Diabetic osteoporosis (DOP) can cause abnormal brain neural activity, but its mechanism is still unclear. This study aims to further explo...