Flu & URI

Artificial Intelligence Model of Drive-Through Vaccination Simulation.

Planning for mass vaccination against SARS-Cov-2 is ongoing in many countries considering that vaccine will be available for the general public in the near future. Rapid mass vaccination while a pandemic is ongoing requires the use of traditional and new temporary vaccination clinics. Use of drive-through has been suggested as one of the possible effective temporary mass vaccinations among other m...

Design of novel orotransmucosal vaccine-delivery platforms using artificial intelligence.

The linings of the oral cavity are excellent needle-free vaccination sites, able to induce immune responses at distal sites and confer systemic protection. However, owing to the mucosal tissues' intrinsic characteristics, the design of effective antigen-delivery systems is not an easy task. In the present work, we propose to develop and characterize thermosensitive and mucoadhesive hydrogels for o...

Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2 leading to universal blueprints for vaccine designs.

The global population is at present suffering from a pandemic of Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus Severe Acute Res...

Repurposing potential of FDA-approved and investigational drugs for COVID-19 targeting SARS-CoV-2 spike and main protease and validation by machine learning algorithm.

The present study aimed to assess the repurposing potential of existing antiviral drug candidates (FDA-approved and investigational) against SARS-CoV-...

Hepatitis C viral load and genotypes among Nigerian subjects with chronic infection and implication for patient management: a retrospective review of data.

INTRODUCTION: Hepatitis C Virus (HCV) is highly infectious with no currently available vaccine. Prior to treatment, it is recommended to confirm HCV i...

How to Determine the Early Warning Threshold Value of Meteorological Factors on Influenza through Big Data Analysis and Machine Learning.

Infectious diseases are a major health challenge for the worldwide population. Since their rapid spread can cause great distress to the real world, in...

Development of machine learning models to predict RT-PCR results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with influenza-like symptoms using only basic clinical data.

BACKGROUND: Reverse Transcription-Polymerase Chain Reaction (RT-PCR) for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) diagnosis curren...

Predicted Cellular Immunity Population Coverage Gaps for SARS-CoV-2 Subunit Vaccines and Their Augmentation by Compact Peptide Sets.

Subunit vaccines induce immunity to a pathogen by presenting a component of the pathogen and thus inherently limit the representation of pathogen pept...

Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools.

The outbreak of SARS-CoV-2 (2019-nCoV) virus has highlighted the need for fast and efficacious vaccine development. Stimulation of a proper immune res...

Performance evaluation of machine learning-based infectious screening flags on the HORIBA Medical Yumizen H550 Haematology Analyzer for vivax malaria and dengue fever.

BACKGROUND: Automated detection of malaria and dengue infection has been actively researched for more than two decades. Although many improvements hav...

Virtual screening of anti-HIV1 compounds against SARS-CoV-2: machine learning modeling, chemoinformatics and molecular dynamics simulation based analysis.

COVID-19 caused by the SARS-CoV-2 is a current global challenge and urgent discovery of potential drugs to combat this pandemic is a need of the hour....

Repurposing therapeutics for COVID-19: Rapid prediction of commercially available drugs through machine learning and docking.

BACKGROUND: The outbreak of the novel coronavirus disease COVID-19, caused by the SARS-CoV-2 virus has spread rapidly around the globe during the past...

Comparing machine learning with case-control models to identify confirmed dengue cases.

In recent decades, the global incidence of dengue has increased. Affected countries have responded with more effective surveillance strategies to dete...

A gradient boosting machine learning approach in modeling the impact of temperature and humidity on the transmission rate of COVID-19 in India.

Meteorological parameters were crucial and effective factors in past infectious diseases, like influenza and severe acute respiratory syndrome (SARS),...

Use of Deep Learning to Analyze Social Media Discussions About the Human Papillomavirus Vaccine.

IMPORTANCE: Human papillomavirus (HPV) vaccine hesitancy or refusal is common among parents of adolescents. An understanding of public perceptions fro...

An Interpretable Predictive Model of Vaccine Utilization for Tanzania.

Providing accurate utilization forecasts is key to maintaining optimal vaccine stocks in any health facility. Current approaches to vaccine utilizatio...

Influenza Screening via Deep Learning Using a Combination of Epidemiological and Patient-Generated Health Data: Development and Validation Study.

BACKGROUND: Screening for influenza in primary care is challenging due to the low sensitivity of rapid antigen tests and the lack of proper screening ...

Measuring and Preventing COVID-19 Using the SIR Model and Machine Learning in Smart Health Care.

COVID-19 presents an urgent global challenge because of its contagious nature, frequently changing characteristics, and the lack of a vaccine or effec...

2019 Novel Coronavirus-Infected Pneumonia on CT: A Feasibility Study of Few-Shot Learning for Computerized Diagnosis of Emergency Diseases.

COVID-19 is an emerging disease with transmissibility and severity. So far, there are no effective therapeutic drugs or vaccines for COVID-19. The mos...

Development of a prognostic model for mortality in COVID-19 infection using machine learning.

Coronavirus disease 2019 (COVID-19) is a novel disease resulting from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), whi...