Fungal Infection

A critical review on occurrence, speciation, mobilization, and toxicity of per- and polyfluoroalkyl substances in the soil-microbe-plant system and bioremediation strategies.

Per- and polyfluoroalkyl substances (PFAS) are a group of recalcitrant anthropogenic compounds that are extensively utilized for numerous industrial applications globally. Despite such vast utilization, PFAS accumulation in the soils and sediments with further uptake, toxicity and translocation to the plants, microbes and microhabitats has led a serious concern. The present review primarily focuse...

Recent research frontiers of heterocycles as antifungal Agents: Insights from the past five years.

This review explores the growing global concern of fungal infections, particularly in immunocompromised individuals, and highlights the critical need for improved antifungal therapies. With the rise of multidrug-resistant strains, such as Candida auris and Aspergillus fumigatus, current antifungal treatments face limitations, including toxicity, low bioavailability, and the development of resistan...

Analysing protein complexes in plant science: insights and limitation with AlphaFold 3.

AlphaFold 3 (AF3), an artificial intelligence (AI)-based software for protein complex structure prediction, represents a significant advancement in st...

Landscape of essential growth and fluconazole-resistance genes in the human fungal pathogen Cryptococcus neoformans.

Fungi can cause devastating invasive infections, typically in immunocompromised patients. Treatment is complicated both by the evolutionary similarity...

Exploring Hidden Dangers: Predicting Mycotoxin-like Toxicity and Mapping Toxicological Networks in Hepatocellular Carcinoma.

Mycotoxins are potent triggers of hepatocellular carcinoma (HCC) due to their intricate interplay with cellular macromolecules and signaling pathways....

Advanced droplet microfluidic platform for high-throughput screening of industrial fungi.

Industrial fungi are pivotal candidates for the production of a diverse array of bioproducts. To enhance their productivity, these strains are frequen...

Editorial: Advancing sustainable management of fungal diseases in berry crops.

Multiple mutations in succinate dehydrogenase subunits conferring resistance to fungicide Pydiflumetofen in Magnaporthe oryzae.

BACKGROUND: Magnaporthe oryzae is the causal agent of rice blast disease. Pydiflumetofen, a novel succinate dehydrogenase inhibitor (SDHI), has promis...

Design and synthesis of novel cinnamamide derivatives-based lansiumamide B as potent fungicidal candidates.

BACKGROUND: Natural products have been and continue to be a significant resource for developing environmentally friendly pesticides with distinctive s...

Variations of the chemical components and biological activities of Thymus capitatus essential oil from three regions in Palestine.

Thymus capitatus is a widely utilized medicinal plant in Palestine. The main goal of this study was to assess the phytochemical content of T. capitatu...

In vitro antimicrobial and anticancer potentials of green synthesized luminescent carbon quantum dots derived from artichoke leaves.

Naturally derived carbon quantum dots (CQDs) are novel carbon-based nanomaterials with excellent traits. It is highly demanded to develop CQDs from bi...

Temporal wheat proteome remodeling by deoxynivalenol reveals novel detoxification signatures and strategies across cultivars.

Fusarium head blight (FHB) is a globally devastating fungal disease resulting in reduced grain yield and quality, along with contamination of grains w...

Investigating endophytic fungi of Calotropis procera for novel bioactive compounds: molecular docking and bioactivity insights.

BACKGROUND: The rising danger of antibiotic resistance and the increasing burden of cancer worldwide have highlighted the necessity for a constant sup...

Bioactivity and chemical screening of endophytic fungi associated with seaweeds Gracilaria sp. and Sargassum sp. of the Bay of Bengal, Bangladesh.

This study explored the great potential of endophytic fungi associated with red seaweed Gracilaria sp. and brown seaweed Sargassum sp. of the Bay of B...

Functions and Mechanisms of Secreted Proteinaceous Effectors of Broad-Host-Range Necrotrophic Fungal Pathogens.

This review focuses on the intricate interaction mechanisms between necrotrophic fungal pathogens and their host plants, emphasizing the pivotal role ...

Neural networks for the prediction of bacterial and fungal infections: current evidence and implications.

In the present narrative review, we discuss the use of artificial neural networks (ANNs) for predicting bacterial and fungal infections based on commo...

Identification of potential riboswitch elements in Homo sapiens mRNA 5'UTR sequences using positive-unlabeled machine learning.

Riboswitches are a class of noncoding RNA structures that interact with target ligands to cause a conformational change that can then execute some reg...

Deep learning based ensemble model for accurate tomato leaf disease classification by leveraging ResNet50 and MobileNetV2 architectures.

Global food security depends on tomato growing, but several fungal, bacterial, and viral illnesses seriously reduce productivity and quality, therefor...

Consecutive low-frequency shifts in A/T content denote nucleosome positions across microeukaryotes.

Nucleosomes are the basic repeating unit, each spanning ≈150bp, that structures DNA in the nucleus and their positions have major consequences on gene...

MALDI-TOF mass spectrometry combined with machine learning algorithms to identify protein profiles related to malaria infection in human sera from Côte d'Ivoire.

BACKGROUND: In sub-Saharan Africa, Plasmodium falciparum is the most prevalent species of malaria parasites. In endemic areas, malaria is mainly diagn...