Fungal Infection

Machine learning enables identification of an alternative yeast galactose utilization pathway.

How genomic differences contribute to phenotypic differences is a major question in biology. The recently characterized genomes, isolation environments, and qualitative patterns of growth on 122 sources and conditions of 1,154 strains from 1,049 fungal species (nearly all known) in the yeast subphylum Saccharomycotina provide a powerful, yet complex, dataset for addressing this question. We used a...

iAFPs-Mv-BiTCN: Predicting antifungal peptides using self-attention transformer embedding and transform evolutionary based multi-view features with bidirectional temporal convolutional networks.

Globally, fungal infections have become a major health concern in humans. Fungal diseases generally occur due to the invading fungus appearing on a specific portion of the body and becoming hard for the human immune system to resist. The recent emergence of COVID-19 has intensely increased different nosocomial fungal infections. The existing wet-laboratory-based medications are expensive, time-con...

Enhancing pediatric pneumonia diagnosis through masked autoencoders.

Pneumonia, an inflammatory lung condition primarily triggered by bacteria, viruses, or fungi, presents distinctive challenges in pediatric cases due t...

INTERPRETABLE MACHINE LEARNING FOR PREDICTING RISK OF INVASIVE FUNGAL INFECTION IN CRITICALLY ILL PATIENTS IN THE INTENSIVE CARE UNIT: A RETROSPECTIVE COHORT STUDY BASED ON MIMIC-IV DATABASE.

The delayed diagnosis of invasive fungal infection (IFI) is highly correlated with poor prognosis in patients. Early identification of high-risk patie...

A high-speed microscopy system based on deep learning to detect yeast-like fungi cells in blood.

Blood-invasive fungal infections can cause the death of patients, while diagnosis of fungal infections is challenging. A high-speed microscopy detec...

Novel graph-based machine-learning technique for viral infectious diseases: application to influenza and hepatitis diseases.

BACKGROUND: Most infectious diseases are caused by viruses, fungi, bacteria and parasites. Their ability to easily infect humans and trigger large-sca...

Chemical composition, antioxidant, and antimicrobial properties of : in sight and analysis.

Our research focused on assessing essential oils (MSEO) and aqueous extracts (MSAE) derived from M. subtomentella leaves, with a primary focus on eval...

Coordinating virus research: The Virus Infectious Disease Ontology.

The COVID-19 pandemic prompted immense work on the investigation of the SARS-CoV-2 virus. Rapid, accurate, and consistent interpretation of generated ...

Antifungal activity of eumelanin-inspired indoylenepheyleneethynylene against .

is an opportunistic fungal pathogen that causes meningitis in >152,000 immunocompromised individuals annually, leading to 112,000 yearly deaths. The ...

Production of natural flavor compounds using fermented soybean meal extract and their biological potential: a comprehensive study.

This study aims to investigate the production of natural flavor compounds through the utilization of -fermented soybean meal extract and evaluate thei...

Effective microorganisms input efficiently improves the vegetation and microbial community of degraded alpine grassland.

Soil beneficial microorganism deficiency in the degraded grasslands have emerged as the major factors negatively impacting soil quality and vegetation...

characterization and molecular epidemiology of spp. isolates from non-HIV patients in Guangdong, China.

BACKGROUND: The burden of cryptococcosis in mainland China is enormous. However, the characterization and molecular epidemiology in Guangdong, a key ...

Efficient production and characterization of melanin from SP1, isolated from the coal mines of Chhattisgarh, India.

In the present study, fungi were isolated and screened from barren land in south-eastern Coalfields limited (SECL) in Chhattisgarh, India. Out of 14 i...

Antifungal activity of the repurposed drug disulfiram against .

Fungal infections have become clinically challenging owing to the emergence of drug resistance in invasive fungi and the rapid increase in the number ...

The critical role of neutrophil-endothelial cell interactions in sepsis: new synergistic approaches employing organ-on-chip, omics, immune cell phenotyping and modeling to identify new therapeutics.

Sepsis is a global health concern accounting for more than 1 in 5 deaths worldwide. Sepsis is now defined as life-threatening organ dysfunction caused...

Anti-ultraviolet, antibacterial, and biofilm eradication activities against of melanins and melanin derivatives from and .

and produced significant amounts of water-insoluble melanins, and our previous study successfully enhanced their water solubility by arginine modifi...

Taxonomy, biological characterization and fungicide sensitivity assays of Hypomyces cornea sp. nov. causing cobweb disease on Auricularia cornea.

Auricularia cornea is an important edible mushroom crop in China but the occurrence of cobweb disease has cause significance economic loss in its prod...

Natural Occurrence of Fungi and Aflatoxins Associated Sugarcane Plant and Sugarcane Juice and Their Control.

Sugarcane is one of the most important crops in the world. It is also considered the most popular fresh juice in Egypt. The sugar content of the sugar...

Antifungal Activity of Thirty Essential Oils to Control Pathogenic Fungi of Postharvest Decay.

Essential oils (EOs) extracted from aromatic or medicinal plants are biodegradable, safe, and regarded as alternatives to chemical pesticides to reduc...

Anti-Staphylococcal, Anti-Candida, and Free-Radical Scavenging Potential of Soil Fungal Metabolites: A Study Supported by Phenolic Characterization and Molecular Docking Analysis.

and are recognized as causative agents in numerous diseases, and the rise of multidrug-resistant strains emphasizes the need to explore natural sour...