Gastroenterology

Latest AI and machine learning research in gastroenterology for healthcare professionals.

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An algorithm for the classification of mRNA patterns in eosinophilic esophagitis: Integration of machine learning.

BACKGROUND: Diagnostic evaluation of eosinophilic esophagitis (EoE) remains difficult, particularly the assessment of the patient's allergic status.

Dec 19 2017 29273402

5-fluorouracil combined with cisplatin and mitomycin C as an optimized regimen for hyperthermic intraperitoneal chemotherapy in gastric cancer.

BACKGROUND AND OBJECTIVES: Optimized drug regimens for hyperthermic intraperitoneal chemotherapy (HIPEC) have not been standardized completely in patients with advanced gastric cancer (GC). We evaluated an optimized anti-tumor protocol comprising 5-fluorouracil (5-FU) combined with cisplatin (CDDP) and mitomycin C (MMC) in vitro for clinical use of HIPEC.

Dec 19 2017 29266509
Elevation of serum pyruvate kinase M2 (PKM2) in IBD and its relationship to IBD indices.

OBJECTIVES: Endoscopy remains the gold standard to diagnose and evaluate inflammatory bowel disease (IBD) activity. Current biomarkers or their combin...

Dec 19 2017 29273328
Serum microRNA panel excavated by machine learning as a potential biomarker for the detection of gastric cancer.

Early detection of gastric cancer (GC) is crucial to improve the therapeutic effect and prolong the survival of patients. MicroRNAs (miRNAs) are a gro...

Dec 19 2017 29286167
Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea.

Stress-induced diarrhea is a frequent and challenging threat to humans and domestic animals. Serotonin (5-HT) has been shown to be involved in the pat...

Dec 19 2017 29260435
Enhanced antitumor efficacy of doxorubicin-encapsulated halloysite nanotubes.

To improve the antitumor efficacy of doxorubicin (DOX) and provide novel clinical treatment of gastric cancer, halloysite nanotubes (HNTs) loaded with...

Dec 19 2017 29296083
Triple-stapled quadrilateral anastomosis: a new technique for creation of an esophagogastric anastomosis.

BACKGROUND: Esophagogastric anastomosis performed after esophagectomy is technically complex and often the source of postoperative complications. The ...

Dec 16 2017 29892931
Symtosis: A liver ultrasound tissue characterization and risk stratification in optimized deep learning paradigm.

Background and Objective Fatty Liver Disease (FLD) - a disease caused by deposition of fat in liver cells, is predecessor to terminal diseases such as...

Dec 16 2017 29512496
Hydrogen protects against liver injury during CO pneumoperitoneum in rats.

The aim of the current study was to identify the protective effect of hydrogen gas against liver injury during CO pneumoperitoneum. Rats were randomly...

Dec 15 2017 29416797
Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC).

BACKGROUND: DNA methylation has been implicated as a promising biomarker for precise cancer diagnosis. However, limited DNA methylation-based biomarke...

Dec 15 2017 29270239
Florfenicol pharmacokinetics following intravenous and oral administrations and its elimination after oral and bath administrations in common carp .

The aim of this study was to evaluate pharmacokinetic profiles of florfenicol after a single dose of intravenous (5.00 mg kg body weight) and oral (40...

Dec 15 2017 29326792
Antigiardial Effect of Kramecyne in Experimental Giardiasis.

A variety of drugs are used in giardiasis treatment with different levels of efficiency, presence of side effects, and even formation of resistant str...

Dec 13 2017 29387130
Hybrid Method Based on Information Gain and Support Vector Machine for Gene Selection in Cancer Classification.

It remains a great challenge to achieve sufficient cancer classification accuracy with the entire set of genes, due to the high dimensions, small samp...

Dec 12 2017 29246519
Development of Decision Forest Models for Prediction of Drug-Induced Liver Injury in Humans Using A Large Set of FDA-approved Drugs.

Drug-induced liver injury (DILI) presents a significant challenge to drug development and regulatory science. The FDA's Liver Toxicity Knowledge Base ...

Dec 11 2017 29229971
Anti-Lipase Potential of the Organic and Aqueous Extracts of Ten Traditional Edible and Medicinal Plants in Palestine; a Comparison Study with Orlistat.

Herbs have played a fundamental and essential role in the humans life since ancient times, especially those which are used as food and/or folk medici...

Dec 8 2017 29292744
Identification of recent cases of hepatitis C virus infection using physical-chemical properties of hypervariable region 1 and a radial basis function neural network classifier.

BACKGROUND: Identification of acute or recent hepatitis C virus (HCV) infections is important for detecting outbreaks and devising timely public healt...

Dec 6 2017 29244000
The addition of inulin and Lactobacillus casei 01 in sheep milk ice cream.

The effect of the Lactobacillus casei 01 and inulin addition on sheep milk ice cream during storage (-18 °C, 150 days) was investigated. Control, prob...

Dec 5 2017 29291874
Robotic assisted gait as a tool for rehabilitation of individuals with spinal cord injury: a systematic review.

BACKGROUND: Spinal cord injury (SCI) is characterized by a total or partial deficit of sensory and motor pathways. Impairments of this injury compromi...

Dec 4 2017 29202845
extract inhibits hepatocellular carcinoma via induction of caspase-dependent apoptosis.

INTRODUCTION: Cancer is a disease with a global burden and is a major and increasing threat to public health. The demand for new modalities to treat a...

Dec 4 2017 29270021
Cannabidiol Does Not Convert to Δ-Tetrahydrocannabinol in an Animal Model.

Cannabidiol (CBD) can convert to Δ-tetrahydrocannabinol (THC) with prolonged exposure to simulated gastric fluid; however, conditions may not be re...

Dec 1 2017 29285522
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