Gastroenterology

Latest AI and machine learning research in gastroenterology for healthcare professionals.

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Identification of potentially oncogenic alterations from tumor-only samples reveals Fanconi anemia pathway mutations in bladder carcinomas.

Cancer is caused by germline and somatic mutations, which can share biological features such as amino acid change. However, integrated germline and somatic analysis remains uncommon. We present a framework that uses machine learning to learn features of recurrent somatic mutations to (1) predict somatic variants from tumor-only samples and (2) identify somatic-like germline variants for integrated...

Oct 3 2017 29263839

Upgrade Combination Response Is Limited by Prolonged Nucelos(t)ide Analogue Therapy in HBeAg-positive Chronic Hepatitis B: A Real-life Study.

Few previous studies have reported on a combination response (hepatitis B virus (HBV) DNA undetected, alanine aminotransferase normalization and hepatitis B e antigen (HBeAg) seroconversion) following nucleos(t)ide analogue (NAs) long-term therapy in patients with chronic hepatitis B (CHB). This study aimed to investigate the combination response on long-term NAs therapy in patients with HBeAg-po...

Sep 30 2017 29577027
A successful case of a para-aortic lymphocele treated with autologous peripheral blood injection.

A lymphocele is one of the complications of systematic pelvic or para-aortic lymphadenectomy. Although most patients are entirely asymptomatic, our pa...

Sep 28 2017 29484065
A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae.

(Wuweizi in Chinese), a common traditional Chinese herbal medicine, has been used for centuries to treat chronic liver disease. The therapeutic effic...

Sep 28 2017 28956809
Serum levels of chemical elements in esophageal squamous cell carcinoma in Anyang, China: a case-control study based on machine learning methods.

OBJECTIVES: Esophageal squamous cell carcinoma (ESCC) is the predominant form of esophageal carcinoma with extremely aggressive nature and low surviva...

Sep 24 2017 28947442
Pharmacokinetics, bioavailability, tissue distribution and excretion of tangeretin in rat.

Tangeretin, 4',5,6,7,8-pentamethoxyflavone, is one of the major polymethoxyflavones (PMFs) existing in citrus fruits, particularly in the peels of swe...

Sep 22 2017 29567257
Risk Prediction for Portal Vein Thrombosis in Acute Pancreatitis Using Radial Basis Function.

BACKGROUND: Acute pancreatitis (AP) can induce portosplenomesenteric vein thrombosis (PVT), which may generate higher morbidity and mortality. However...

Sep 22 2017 28943487
Combined effects of chitosan and microencapsulated CG1.0007 probiotic supplementation on performance and diarrhea incidences in enterotoxigenic K88 challenged piglets.

The aim of this study was to investigate the combined effects of chitosan oligosaccharide (COS) and a microencapsulated CG1.0007 probiotic (PRO) on g...

Sep 21 2017 29767090
Survivability prediction of colon cancer patients using neural networks.

We utilize deep neural networks to develop prediction models for patient survival and conditional survival of colon cancer. Our models are trained and...

Sep 19 2017 28927314
Effect of combined farnesoid X receptor agonist and angiotensin II type 1 receptor blocker on hepatic fibrosis.

The farnesoid X receptor (FXR) agonist, a bile acid-activated nuclear receptor, has been shown to improve the histologic features of nonalcoholic stea...

Sep 19 2017 29404501
Evaluation of thyme and ajwain as antibiotic growth promoter substitutions on growth performance, carcass characteristics and serum biochemistry in Japanese quails ().

The present study was to evaluate thyme and ajwain as antibiotic growth promoter substitutions on growth performance, carcass characteristics and seru...

Sep 18 2017 30167488
Computer-assisted cytologic diagnosis in pancreatic FNA: An application of neural networks to image analysis.

BACKGROUND: Fine-needle aspiration (FNA) biopsy is an accurate method for the diagnosis of solid pancreatic masses. However, a significant number of c...

Sep 8 2017 28885766
Intelligent visual localization of wireless capsule endoscopes enhanced by color information.

Wireless capsule endoscopy (WCE) is performed with a miniature swallowable endoscope enabling the visualization of the whole gastrointestinal (GI) tra...

Sep 1 2017 28886480
DRMDA: deep representations-based miRNA-disease association prediction.

Recently, microRNAs (miRNAs) are confirmed to be important molecules within many crucial biological processes and therefore related to various complex...

Aug 31 2017 28857494
Comparison of hydrocortisone and prednisone in the glucocorticoid replacement therapy post-adrenalectomy of Cushing's Syndrome.

Cushing's syndrome requires glucocorticoid replacement following adrenalectomy. Based on a simplified glucocorticoid therapy scheme and the peri-opera...

Aug 31 2017 29285318
Nonparametric Online Learning Control for Soft Continuum Robot: An Enabling Technique for Effective Endoscopic Navigation.

Bioinspired robotic structures comprising soft actuation units have attracted increasing research interest. Taking advantage of its inherent complianc...

Aug 28 2017 29251567
Optimized preparation of anthocyanin-rich extract from black rice and its effects on in vitro digestibility.

The procedure for obtaining anthocyanin-enriched extracts from black rice was optimized by response surface methodology, and the effects of the optimi...

Aug 28 2017 30263677
Early Colorectal Cancer Detected by Machine Learning Model Using Gender, Age, and Complete Blood Count Data.

BACKGROUND: Machine learning tools identify patients with blood counts indicating greater likelihood of colorectal cancer and warranting colonoscopy r...

Aug 23 2017 28836087
Use of Mac-2 binding protein as a biomarker for nonalcoholic fatty liver disease diagnosis.

In contrast to patients with viral hepatitis, patients with nonalcoholic fatty liver disease (NAFLD) can progress to hepatocellular carcinoma during t...

Aug 16 2017 29404494
Effect of deoxynivalenol on apoptosis, barrier function, and expression levels of genes involved in nutrient transport, mitochondrial biogenesis and function in IPEC-J2 cells.

This study was conducted to determine the effect of 200 ng mL and 2000 ng mL deoxynivalenol (DON) on apoptosis, barrier function, nutrient transporter...

Aug 15 2017 30090549
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