Gastroenterology

Identifying cathepsin B as a key regulator of programmed cell death in acute pancreatitis.

Acute pancreatitis (AP) lacks effective therapies, and excessive programmed cell death (PCD) drives ...

Standardized scoring systems-essential for the AI Era in small-bowel capsule endoscopy.

Radiomics and artificial intelligence in pancreatic cyst characterization: future or fiction?

Pancreatic cystic lesions (PCLs) are increasingly detected due to the widespread use of cross-sectio...

Radiomics based on multiphasic contrast-enhanced CT combined with clinical features for differentiating hypovascular pancreatic neuroendocrine tumors and pancreatic ductal adenocarcinoma.

Toward Precise Risk Stratification after the Functional Cure of Chronic Hepatitis B.

Chronic hepatitis B remains a major global health challenge despite the advances in antiviral therap...

Artificial intelligence-based reclassification of gastric adenocarcinoma enables prognostic stratification via diffuse-type patch proportion.

BACKGROUND: Gastric adenocarcinoma (GAC) remains a major global health burden with marked heterogene...

Delisting From Clinical Improvement in Liver Cirrhosis: A Machine Learning Decision Tree Analysis.

BACKGROUND: Following therapeutic advancements, recompensation has gained increasing recognition in ...

Machine learning-based identification of key genes underlying sex differences in hepatocellular carcinoma and targeted drug screening.

Hepatocellular carcinoma (HCC) shows a marked predominance in men, yet the molecular basis for this ...

Prediction of trajectories and outcomes in early-stage metabolic dysfunction-associated steatotic liver disease: a narrative review.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver...

Artificial Intelligence in Colonoscopy Surveillance for Lynch Syndrome: Emerging Evidence, Lessons Learned From Average-Risk Populations, and Future Directions.

Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome and is characteri...

Urinary Metabolomics and One-Class Classification To Discover Children Affected by Bile Acid Synthetic Disorders: A Case-Study.

Bile acid synthetic disorders (BASDs) are a group of rare metabolic disorders that involve the synth...

In Silico Prediction of Potential Bile Salt Export Pump Inhibitors Using Pharmacophore Models and Consensus Machine Learning.

The ATP-dependent bile salt export pump (BSEP) is a transporter responsible for moving bile salts fr...

Deep learning-based renal artery segmentation and angle estimation for registration of endoscopic images and 3D models in robot-assisted partial nephrectomy.

PURPOSE: Image-guided robot-assisted partial nephrectomy (RAPN) that incorporates three-dimensional ...

A time-series feature-based nomogram for the prediction of severe acute pancreatitis.

Integrating multi-omics data for enhanced prognosis prediction in gastric cancer post-neoadjuvant therapy.

BACKGROUND: Neoadjuvant therapy is crucial for locally advanced gastric cancer (LAGC), yet response ...

Machine Learning Analysis of Serum Metabolomics for Multi-Disease Classification and Proteome-Metabolome Pathway Insights in T2D, IBD, and CRC.

Type 2 diabetes (T2D), inflammatory bowel disease (IBD), and colorectal cancer (CRC) share overlappi...

IL11⁺ fibroblasts are implicated in non-response to anti-TNFα via fibrosis in inflammatory bowel disease.

Inflammatory bowel disease (IBD) is frequently accompanied by intestinal fibrosis, with non-response...

Screening for Colorectal Cancer with Colonoscopy.

Colorectal cancer (CRC) imposes a substantial global burden, with highest incidence in Australia/New...

Early detection and subtyping of gastric cancer: A cell-free DNA fragmentome-based liquid biopsy method.

Cell-free DNA (cfDNA) in plasma provides attractive opportunities for early cancer diagnosis. This s...

Calculation and evaluation of the effective withdrawal time of colonoscopy on the basis of internimage.

Urinary extracellular vesicle miRNA signature reflects pancreatic islet stress in type 2 diabetes.

INTRODUCTION: Type 2 diabetes (T2D) is a progressive metabolic disorder characterized by insulin res...