Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 2101-2121 of 11,076 articles
Non-invasive prediction of DCE-MRI radiomics model on CCR5 in breast cancer based on a machine learning algorithm.

BackgroundNon-invasive methods with universal prognostic guidance for detecting breast cancer (BC) s...

May 2025 40395152
A pathway-informed disease-related gene identification approach and its application to screen novel risk genes for Alzheimer's disease.

BACKGROUND: Alzheimer's disease (AD) is a severe neurodegenerative disorder, yet its molecular mecha...

May 2025 40406678
Imaging patterns and recommendations for diagnosis, staging, and management of lung cancer.

Lung cancer is the second most commonly diagnosed cancer worldwide. In the present era of targeted t...

May 2025 40486071
Microbial vitamin biosynthesis links gut microbiota dynamics to chemotherapy toxicity.

Dose-limiting toxicities pose a major barrier to cancer treatment. While preclinical studies show th...

May 2025 40391895
Genomics-assisted breeding for designing salinity-smart future crops.

Climate change induces many abiotic stresses, including soil salinity, significantly challenging glo...

May 2025 40390692
XVir: A Transformer-Based Architecture for Identifying Viral Reads from Cancer Samples.

It is estimated that approximately 15% of cancers worldwide can be linked to viral infections. The v...

May 2025 40392695
An artificial intelligence-based model for prediction of clonal hematopoiesis variants in cell-free DNA samples.

Circulating tumor DNA is a critical biomarker in cancer diagnostics, but its accurate interpretation...

May 2025 40394286
CMImpute: cross-species and tissue imputation of species-level DNA methylation samples across mammalian species.

The large-scale application of the mammalian methylation array has substantially expanded the availa...

May 2025 40394556
Integrating Artificial Intelligence and Precision Therapeutics for Advancing the Diagnosis and Treatment of Age-Related Macular Degeneration.

Age-related macular degeneration (AMD) is a multifactorial retinal disease influenced by complex mol...

May 2025 40428167
Integration of Bulk and Single-Cell RNA Sequencing to Identify RNA Modifications-Related Prognostic Signature in Ovarian Cancer.

BACKGROUND: Ovarian cancer (OC), a common fatal malignancy in women, has a poor prognosis. RNA modif...

May 2025 40417417
Application of temperature replica exchange molecular dynamics: Structure of mitotic spindle-associated protein SHE1 and its binding to dynein.

Cytoskeletal motor protein dynein belongs to the AAA+ superfamily of enzymes, functioning as a mecha...

May 2025 40529183
Sex-Based Differences in Prenatal and Perinatal Predictors of Autism Spectrum Disorder Using Machine Learning With National Health Data.

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder influenced by genetic, epige...

May 2025 40384623
The Future of Parasomnias.

Parasomnias are abnormal behaviours or mental experiences during sleep or the sleep-wake transition....

May 2025 40387303
Whole-Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib.

OBJECTIVE: Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK...

May 2025 40388487
Novel marker genes and small molecule drugs for radiotherapy resistance in cervical cancer identified based on single-cell multi-omics analysis.

Radiotherapy is the cornerstone of treatment for cervical cancer, yet the variability of patient res...

May 2025 40389794
Integrative analysis of epigenetic and transcriptional interrelations identifies histotype-specific biomarkers in early-stage ovarian carcinoma.

BACKGROUND: Epithelial ovarian cancer (EOC) is a deadly and heterogenous disease comprising five maj...

May 2025 40390000
An integrated multiscale computational framework deciphers SARS-CoV-2 resistance to sotrovimab.

The emergence of resistance mutations in the SARS-CoV-2 spike (S) protein presents a challenge for m...

May 2025 40394898
Integration of structural study and machine learning to elucidate the RNA-SFs interaction atlas in eukaryotic cells.

Alternative splicing (AS) occupies a central position in plant growth and development, stress respon...

May 2025 40398644
Association of [F]-FDG PET/CT-Derived Radiomic Features with Clinical Outcomes and Genomic Profiles in Patients with Chronic Lymphocytic Leukemia.

The role of PET/CT imaging in chronic lymphoproliferative syndromes (CLL) is debated. This study ex...

May 2025 40428274
Investigation of the Significance of Blood Signatures on Sepsis-Induced Acute Lung Injury in Sepsis Within 24 Hours.

Sepsis is an infection-induced dysregulated cellular response that leads to multiorgan dysfunction....

May 2025 40421173
Integrating next-generation sequencing and artificial intelligence for the identification and validation of pathogenic variants in colorectal cancer.

BACKGROUND: Colorectal cancer (CRC) is recognized as a multifactorial disease, where both genetic an...

May 2025 40458721
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