Latest AI and machine learning research in genetics for healthcare professionals.
The Aedes aegypti mosquito is a vector for human arboviruses and zoonotic diseases and therefore poses a serious threat to public health. Understanding how Ae. aegypti adapts to environmental pressures-such as insecticides-is critical for developing effective mitigation strategies. However, most traditional methods for detecting recent positive selection search for signatures of classic "hard" sel...
INTRODUCTION: Age acceleration in survivors of breast cancer is a critical issue because cancer and its treatment can increase structural and numerical chromosomal aberrations, while simultaneously shortening telomere length and changing ageing phenotype. Therefore, the current study will be using machine learning architectures to accurately predict the factors that contribute to age acceleration ...
BACKGROUND: Fatal occupational injury rates among agricultural workers are within the top 10 most dangerous civilian jobs. However, tracking and docum...
BACKGROUND AND PURPOSE: Pediatric low-grade gliomas (pLGGs) are the most common brain tumors in children and frequently harbor BRAF alterations, most ...
BACKGROUND: Eosinophilic esophagitis (EoE) and its related subtypes-such as EoE-like esophagitis, lymphocytic esophagitis, and nonspecific esophagitis...
BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection and remains a major global health chall...
Intracellular delivery of therapeutic biomolecules represents a fundamental prerequisite for cell-based therapies and precision medicine, yet existing...
BACKGROUND: Emerging evidence highlights the pivotal role of ferroptosis in the pathophysiology of diabetic nephropathy (DN). This study aimed to iden...
Cell migration underlies immune surveillance, tissue repair, embryogenesis, and-when dysregulated-tumor metastasis. Yet unlike proliferation, which ca...
Heterogeneity in cancer gene expression is typically linked to genetic and epigenetic alterations, yet the extent of contribution from posttranscripti...
G-quadruplexes (G4s) and i-motifs (iMs) are emerging as key cis-regulatory elements in plant genomes, functioning at both DNA and RNA levels. This rev...
Single-cell RNA sequencing (scRNA-seq) provides an instantaneous snapshot of the transcriptional state of a cell, which results from the simultaneous ...
Aging is a major risk factor for neurodegenerative diseases, yet the underlying epigenetic mechanisms remain unclear. Here, we generated a comprehensi...
Drug resistance is a major challenge in cancer and infectious diseases, requiring innovative solutions. Recent research suggests that bacteria and can...
BRAF inhibitors (BRAFi) have transformed the treatment of BRAF mutant melanoma, but inherent and acquired resistance remains a major barrier to curati...
In the Krebs cycle, isocitrate dehydrogenase 1 (IDH1) catalyses the conversion of isocitrate (ICT) to α-ketoglutarate (α-KG), generating nicotinamide ...
This study aimed to characterize salivary microbiome compositions that can classify periodontal health and various stages of periodontitis. We collect...
Hybrid seed technology future depends on integrating advanced genomics, AI-driven breeding, and enabling policies to sustainably delivery climate-resi...
A fundamental question in immunology is how the adaptive immune system encodes antigen specificity while maintaining repertoire diversity. B cell rece...
MOTIVATION: MirtronDB provides a comprehensive and up-to-date resource for advancing mirtron research within RNA biology. Therefore, maintaining a spe...