Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 2185-2205 of 11,655 articles
Induced Dipole Calculation with E(3)-Equivariant Neural Networks and Multipole Field Perturbation.

Polarizable force fields based on induced dipoles are widely implemented in molecular dynamics simul...

Mar 2026 41854103
DeepIM: Integrating Channel-Spatial Attention with Transformer for DNA i-Motif Folding Status Prediction.

i-Motif (iM), a quadruplex structure formed by C-rich DNA sequences under acidic conditions, is sign...

(2)
Mar 2026 41854168
Circulating MicroRNA Signatures in Severe Alopecia Areata: Diagnostic Discrimination, Pathway Analysis, and Therapeutic Implications.

INTRODUCTION: Alopecia areata (AA) is an autoimmune disorder characterized by non-scarring hair loss...

Mar 2026 41854972
Critical Assessment of a Structure-Based Pipeline for Targeting the Long Noncoding RNA MALAT1.

Long noncoding RNAs (lncRNAs) are increasingly recognized as druggable targets due to their conserve...

(2)
Mar 2026 41855101
Hypoxia-related and immune phenotype-related fusion model for non-invasive prognostication of hepatocellular carcinoma treated by TACE: a multicentre study.

BACKGROUND: Survival outcomes after transarterial chemoembolisation (TACE) vary in hepatocellular ca...

Mar 2026 41856522
The ATF5-GPER1 axis drives female protection in hepatocellular carcinoma through dual tumor-suppressive and immune-modulatory mechanisms.

Hepatocellular carcinoma (HCC) exhibits marked sexual dimorphism, with females demonstrating superio...

Mar 2026 41850858
Genomic evolution of SARS-CoV-2 delta variants pre- and post-omicron emergence using alignment-free machine learning models.

The SARS-CoV-2 Delta variant (B.1.617.2), initially classified as a variant of concern due to its en...

(2)
Mar 2026 41855150
AbDist: a lightweight, distance-based model for antibody affinity prediction as an interpretable benchmark for machine learning models.

Many complex models for antibody affinity prediction have been developed and successfully deployed. ...

Mar 2026 41847928
MuTemAPR: Enhance Multilocation Patches with Template-Based Neural Program Repair.

Automated program repair (APR) has been studied extensively in recent years. Existing approaches mai...

Mar 2026 41848642
Hyperspectral phenotyping reveals the genetic basis of grain quality in rice.

Rice (Oryza sativa) grain quality is an important breeding target, yet its genetic basis remains inc...

Mar 2026 42003996
EPI-CAT: Prediction of enhancer-promoter interactions based on cross-attention transformer.

BACKGROUND: Enhancer-promoter interactions (EPIs) play a central role in transcriptional regulation,...

Mar 2026 41861881
Identification and validation of NETs-associated biomarkers in osteoporosis with diabetes.

Osteoporosis and diabetes represent major global public health challenges. Neutrophil extracellular ...

Mar 2026 41851246
Thymic health and immunotherapy outcomes in patients with cancer.

Although immunotherapy has revolutionized cancer treatment, many patients still experience limited b...

Mar 2026 41851467
Improving the efficiency of high-fidelity Cas9 by enhancing PAM-distal interactions.

Engineering CRISPR enzymes for high fidelity often impairs cleavage activity. Meanwhile, a mechanist...

Mar 2026 41851507
Identification of hypoxia-related gene signatures and molecular subtypes in chronic rhinosinusitis with nasal polyps.

OBJECTIVES: Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a common and severe subtype of Chro...

Mar 2026 41855680
Precision harvest: path to genetically modified organism-free crops with CRISPR by 2035.

Recent advances in clustered regularly interspaced short palindromic repeats (CRISPR) technology ena...

(1)
Mar 2026 41856885
dMMR prediction from colorectal cancer histopathology: Leveraging non-tumor and low-magnification regions.

BACKGROUND AND OBJECTIVE: Colorectal cancer is the second leading cause of cancer-related mortality ...

(1)
Mar 2026 41875848
Manufacturing-aware generative models enable petascale synthesis of designed DNA.

Generative modeling offers a robust framework for designing functional DNA, RNA and protein sequence...

Mar 2026 41844990
BKDRP: a biological knowledge-driven approach for drug response prediction using multi-omics data in cancer cell lines.

BACKGROUND: Cancer heterogeneity results in patients with the same diagnosis responding differently ...

Mar 2026 41845230
Adaptive Niching-Based Gradient-Accelerated Differential Evolution for High-Dimensional Nonconvex Optimization.

Nonconvex optimization presents significant challenges in many fields, particularly in training deep...

(2)
Mar 2026 41843521
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