Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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CRISPR-Cas-Based Biomonitoring for Marine Environments: Toward CRISPR RNA Design Optimization Via Deep Learning.

Almost all of Earth's oceans are now impacted by multiple anthropogenic stressors, including the spr...

Multi-batch single-cell comparative atlas construction by deep learning disentanglement.

Cell state atlases constructed through single-cell RNA-seq and ATAC-seq analysis are powerful tools ...

The deep arbitrary polynomial chaos neural network or how Deep Artificial Neural Networks could benefit from data-driven homogeneous chaos theory.

Artificial Intelligence and Machine learning have been widely used in various fields of mathematical...

Rm-LR: A long-range-based deep learning model for predicting multiple types of RNA modifications.

Recent research has highlighted the pivotal role of RNA post-transcriptional modifications in the re...

HydRA: Deep-learning models for predicting RNA-binding capacity from protein interaction association context and protein sequence.

RNA-binding proteins (RBPs) control RNA metabolism to orchestrate gene expression and, when dysfunct...

Explainable multi-task learning improves the parallel estimation of polygenic risk scores for many diseases through shared genetic basis.

Many complex diseases share common genetic determinants and are comorbid in a population. We hypothe...

A simulative deep learning model of SNP interactions on chromosome 19 for predicting Alzheimer's disease risk and rates of disease progression.

BACKGROUND: Identifying genetic patterns that contribute to Alzheimer's disease (AD) is important no...

Harnessing the power of artificial intelligence to advance cell therapy.

Cell therapies are powerful technologies in which human cells are reprogrammed for therapeutic appli...

Multi-Constraint Latent Representation Learning for Prognosis Analysis Using Multi-Modal Data.

The Cox proportional hazard model has been widely applied to cancer prognosis prediction. Nowadays, ...

A hierarchical self-attention-guided deep learning framework to predict breast cancer response to chemotherapy using pre-treatment tumor biopsies.

BACKGROUND: Pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) has demonstrated ...

High accuracy epidermal growth factor receptor mutation prediction via histopathological deep learning.

BACKGROUND: The detection of epidermal growth factor receptor (EGFR) mutations in patients with non-...

Prediction of on-target and off-target activity of CRISPR-Cas13d guide RNAs using deep learning.

Transcriptome engineering applications in living cells with RNA-targeting CRISPR effectors depend on...

Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring.

Plasma cell-free DNA (cfDNA) is a noninvasive biomarker for cell death of all organs. Deciphering th...

The prediction of drug sensitivity by multi-omics fusion reveals the heterogeneity of drug response in pan-cancer.

Cancer drug response prediction based on genomic information plays a crucial role in modern pharmaco...

Deep learning applications in single-cell genomics and transcriptomics data analysis.

Traditional bulk sequencing methods are limited to measuring the average signal in a group of cells,...

Sampling effect in predicting the evolutionary response of populations to climate change.

Genomic data and machine learning approaches have gained interest due to their potential to identify...

GR-m6A: Prediction of N6-methyladenosine sites in mammals with molecular graph and residual network.

RNA N6-methyladenine (m6A), which is produced by the methylation of the N6 position of eukaryotic ad...

Noninvasive genetic screening: current advances in artificial intelligence for embryo ploidy prediction.

This review discusses the use of artificial intelligence (AI) algorithms in noninvasive prediction o...

Artificial Intelligence-Assisted Diagnostic Cytology and Genomic Testing for Hematologic Disorders.

Artificial intelligence (AI) is a rapidly evolving field of computer science that involves the devel...

Supervised learning and model analysis with compositional data.

Supervised learning, such as regression and classification, is an essential tool for analyzing moder...

Classification and deep-learning-based prediction of Alzheimer disease subtypes by using genomic data.

Late-onset Alzheimer's disease (LOAD) is the most common multifactorial neurodegenerative disease am...

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