Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 2437-2457 of 11,076 articles
RNA-protein interaction prediction using network-guided deep learning.

Accurate computational determination of RNA-protein interactions remains challenging, particularly w...

Feb 2025 39956833
Breaking barriers: noninvasive AI model for BRAF mutation identification.

OBJECTIVE: BRAF is the most common mutation found in thyroid cancer and is particularly associated w...

Feb 2025 39955452
Identifying RNA-small Molecule Binding Sites Using Geometric Deep Learning with Language Models.

RNAs are emerging as promising therapeutic targets, yet identifying small molecules that bind to the...

Feb 2025 39961524
Cloning, Characterization, and Computer-Aided Evolution of a Thermostable Laccase of the DUF152 Family From Klebsiella michiganensis.

Bacterial laccases exhibit relatively high optimal reaction temperatures and possess a broad substra...

Feb 2025 39950717
A deep-learning model for predicting tyrosine kinase inhibitor response from histology in gastrointestinal stromal tumor.

Over 90% of gastrointestinal stromal tumors (GISTs) harbor mutations in KIT or PDGFRA that can predi...

Feb 2025 39950223
Interpretable AI for inference of causal molecular relationships from omics data.

The discovery of molecular relationships from high-dimensional data is a major open problem in bioin...

Feb 2025 39951525
A Perspective on Artificial Intelligence for Molecular Pathologists.

The widespread adoption of next-generation sequencing technology in molecular pathology has enabled ...

Feb 2025 39954999
Integrating single-cell sequencing and machine learning to uncover the role of mitophagy in subtyping and prognosis of esophageal cancer.

Globally, esophageal cancer stands as a prominent contributor to cancer-related fatalities, distingu...

Feb 2025 39948301
Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.

Hundreds of loci have been robustly associated with obesity-related traits, but functional character...

Feb 2025 39948378
Reliability-enhanced data cleaning in biomedical machine learning using inductive conformal prediction.

Accurately labeling large datasets is important for biomedical machine learning yet challenging whil...

Feb 2025 39946419
metaCDA: A Novel Framework for CircRNA-Driven Drug Discovery Utilizing Adaptive Aggregation and Meta-Knowledge Learning.

In the emerging field of RNA drugs, circular RNA (circRNA) has attracted much attention as a novel m...

Feb 2025 39937612
Self-supervised machine learning methods for protein design improve sampling but not the identification of high-fitness variants.

Machine learning (ML) is changing the world of computational protein design, with data-driven method...

Feb 2025 39937901
Deep learning-based quick MLC sequencing for MRI-guided online adaptive radiotherapy: a feasibility study for pancreatic cancer patients.

One bottleneck of magnetic resonance imaging (MRI)-guided online adaptive radiotherapy is the time-c...

Feb 2025 39883962
DeepInterAware: Deep Interaction Interface-Aware Network for Improving Antigen-Antibody Interaction Prediction from Sequence Data.

Identifying interactions between candidate antibodies and target antigens is a key step in developin...

Feb 2025 39932383
Interpretable deep learning of single-cell and epigenetic data reveals novel molecular insights in aging.

Deep learning (DL) and explainable artificial intelligence (XAI) have emerged as powerful machine-le...

Feb 2025 39934290
Circular RNA-Drug Association Prediction Based on Multi-Scale Convolutional Neural Networks and Adversarial Autoencoders.

The prediction of circular RNA (circRNA)-drug associations plays a crucial role in understanding dis...

Feb 2025 40003977
Comparing statistical learning methods for complex trait prediction from gene expression.

Accurate prediction of complex traits is an important task in quantitative genetics. Genotypes have ...

Feb 2025 39932918
Deep learning for RNA structure prediction.

Predicting RNA structures from sequences with computational approaches is of vital importance in RNA...

Feb 2025 39933218
Machine learning-enhanced surface-enhanced spectroscopic detection of polycyclic aromatic hydrocarbons in the human placenta.

The detection and identification of polycyclic aromatic hydrocarbons (PAHs) and their derivatives, p...

Feb 2025 39928861
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