Latest AI and machine learning research in genetics for healthcare professionals.
Although individual Mendelian diseases-those caused by a single gene-are rare, their collective dise...
DNA N 4-methylcytosine (4mC), a key epigenetic modification regulating DNA repair and replication, r...
Autopsy-derived brain tissue analysis is crucial for understanding neurobiology, but post-mortem han...
BACKGROUND: Early detection of hepatocellular carcinoma (HCC) remains a significant clinical challen...
PURPOSE: Germline pathogenic variants (GPV) are frequently identified as secondary findings in cance...
Cell lines are essential tools for studying biological mechanisms, advancing pre-clinical drug disco...
BACKGROUND: Current atopic dermatitis (AD) therapy selection does not account for molecular drivers ...
Infectious diseases remain a major global public health concern, demanding rapid and accurate identi...
The environmental, ecological, antimicrobial resistance (AMR), and human health risks of antibiotic ...
Immune checkpoint blockade, particularly programmed cell death protein 1 inhibition, has redefined t...
BACKGROUND: Osteoporosis (OP) is characterized by decreased bone mineral density and an increased fr...
Population screening for rare genetic diseases has the potential to increase early diagnosis and tre...
OBJECTIVE: Breast cancer is the most common malignancy in women and is characterized by a high recur...
Chimeric antigen receptor natural killer (CAR-NK) cell therapy is an emerging cancer treatment offer...
UNLABELLED: Genetically engineered mouse models (GEMM) of cancer are useful for exploring the develo...
UNLABELLED: Single-cell RNA sequencing facilitates the discovery of gene expression signatures that ...
Single-cell and single-nucleus RNA sequencing are used to reveal heterogeneity in cells, showing a g...
Sepsis remains one of the most diagnostically challenging syndromes due to its clinical heterogeneit...
Human tumor organoids represent a paradigm shift in cancer modeling, overcoming critical limitations...
Genome editing with CRISPR-Cas systems is revolutionizing medicine, molecular biology and biotechnol...
RNA-dependent protein assemblies - including the spliceosome, ribosome and RNA-dependent membraneles...