Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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FLYNC: a machine-learning-driven framework for discovering long noncoding RNAs in Drosophila melanogaster.

Noncoding RNAs have increasingly recognized roles in critical molecular mechanisms of disease. Howev...

Jan 2026 41551930
Machine learning-based typing of Clostridium botulinum group III by FT-IR spectroscopy.

This study aimed to investigate the utility of Fourier-Transform Infrared Spectroscopy (FT-IRS) for ...

Jan 2026 41537581
Utilisation of Machine Learning Approaches Improves RNA-Seq Transcriptome Analyses in Alzheimer's Disease Brain.

UNLABELLED: Alzheimer’s disease (AD) is a neurodegenerative disorder that progressively deteriorates...

Jan 2026 41537925
Biologically explicable multimodal model predicting local tumor progression and tumor invasiveness of hepatocellular carcinoma.

PURPOSE: Local tumor progression (LTP) of hepatocellular carcinoma (HCC) after thermal ablation (TA)...

Jan 2026 41538135
BreastDCEDL: A standardized deep learning-ready breast DCE-MRI dataset of 2,070 patients.

Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) is essential for monitoring breast ca...

Jan 2026 41540040
GSR-ST: A generalized spatial-temporal framework for genomic signals and regions prediction using multi-scale feature fusion.

Genomic DNA sequences contain diverse functional genomic signals and regions (GSRs) that are crucial...

Jan 2026 41558219
Integrating CAR-T therapy with PD-1/PD-L1 blockade: Mechanisms, synergy, and optimized strategies in NSCLC.

Non-small cell lung cancer (NSCLC) presents persistent challenges in immunotherapy, as the clinical ...

Jan 2026 41675056
Characterizing RNA Tetramer Conformational Landscape Using Explainable Machine Learning.

The conformational flexibility of RNA molecules enables them to play vital physiological roles, incl...

Jan 2026 41532431
Gastric cancer organoids and their convergence in engineering approaches.

Gastric cancer research has rapidly progressed due to interdisciplinary advances in stem cell biolog...

Jan 2026 41532472
Thermophiles in the genomic Era (2015-2025): a review on biodiversity, metagenome-assembled genomes, and future directions.

Thermophile research has been transformed over the past decade by advances in genome sequencing. Onc...

Jan 2026 41532487
Exploring structural diversity and dynamic stability of small-molecule PRMT5 inhibitors through machine learning-based QSAR and molecular modelling.

Protein arginine methyltransferase 5 (PRMT5) is a key epigenetic enzyme that catalyses symmetric arg...

Jan 2026 41533017
Machine learning and multi-omics integration identifies immunological predictors and mechanistic insights in autoimmune encephalitis.

OBJECTIVE: To develop an interpretable prognostic prediction model for autoimmune encephalitis (AE) ...

Jan 2026 41533076
A Boruta-SMOTE Integrated Approach for Rapid Donkey Breed Classification Using SNP Data: Addressing High-Dimensionality and Small Sample Challenges.

With the increasing complexity of genomic data, traditional classification methods face dual challen...

Jan 2026 41533190
Challenges and Opportunities with CRISPR-Based Genome Editing in Legume Crops.

Over the last couple of decades, tremendous progress has been made in legume genomics. Genomics info...

Jan 2026 41533202
Ultrahigh Interfacial Thermal Conductance in Borophene Heterostructures Enabled by the Phonon Bridge.

The rapid integration of nano- and microdevices underscores the critical role of interfacial thermal...

Jan 2026 41533966
Multi-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma.

Medullary thyroid carcinoma (MTC) is a rare, aggressive neuroendocrine tumor with limited treatment ...

Jan 2026 41535264
Comprehensive mapping of RNA modification dynamics and crosstalk via deep learning and nanopore direct RNA-sequencing.

Despite the extensive studies of individual RNA modifications, the lack of methods to detect multipl...

Jan 2026 41535294
Digital CRISPR-based diagnostics for quantification of Candida auris and resistance mutations.

Candida auris, an increasingly prevalent fungal pathogen, requires both rapid identification and ant...

(1)
Jan 2026 41535388
IdentifiHR predicts homologous recombination deficiency in high-grade serous ovarian carcinoma using gene expression.

BACKGROUND: Approximately half of all high-grade serous ovarian carcinomas (HGSCs) have a therapeuti...

(2)
Jan 2026 41535393
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