Latest AI and machine learning research in genetics for healthcare professionals.
Musculoskeletal injuries and interindividual variability in recovery remain critical challenges for sustaining elite athletic performance. Despite advances in diagnostics, training, and rehabilitation, unexplained differences in injury risk and recovery efficiency persist. Growing evidence implicates genetic and epigenetic mechanisms in these disparities, influencing collagen integrity, inflammato...
Endometrial cancer represents a major global health concern, with rising incidence particularly in developed countries despite declining mortality rates. This comprehensive review examines the evolution of endometrial cancer screening techniques, encompassing traditional methods, emerging technologies, and integrated approaches. Traditional screening methods including transvaginal ultrasound and h...
BACKGROUND: Lymph node metastasis is important for the management and surgical procedures of patients with colorectal cancer. Preoperative identificat...
Precision medicine has transformed healthcare by tailoring treatment plans to an individual's genetic profile, in contrast to standardized therapies. ...
Adeno-associated virus (AAV) vectors are excellent gene-delivery carriers in gene therapy; however, improperly packaged capsids produced during manufa...
Microsatellite instability (MSI) has gained increasing attention as a promising biomarker for cancer immunotherapy in diverse cancer types. As a resul...
Transposable elements (TEs) are key drivers of genomic variation and species evolution. Although advances in high-throughput sequencing have enabled p...
Molecular diagnostics have transformed clinical microbiology by enabling rapid, accurate, and highly sensitive detection of infectious agents, signifi...
Liquid biopsies are transforming oncology, enabling earlier diagnosis, dynamic treatment guidance, and personalized precision medicine, yet current ap...
INTRODUCTION: Gastric cancer remains a major global health burden, with high mortality driven by late-stage diagnoses that limit treatment options and...
BACKGROUND & AIMS: The incidence of early-onset colorectal cancer (EOCRC; diagnosed before age 50 years) continues to increase, now standing as the le...
INTRODUCTION: Blood-based biomarkers that can aid diagnosis of Parkinson's Disease (PD) dementia (PDD), and predict PDD onset in people with PD are ur...
Epigenetic macromolecular enzyme complexes tightly regulate gene expression at the chromatin level and have recently been found to colocalize with RNA...
Accurate prediction of IDH mutation status in gliomas is critical for guiding diagnosis, prognosis, and treatment planning. We enrolled 2,537 preopera...
The steady-state abundance of mRNA is governed by the interplay between transcription and degradation, yet the contribution of RNA stability to cancer...
UNLABELLED: Single-cell RNA sequencing (scRNA-seq) technology enables researchers to explore heterogeneity of diverse cell types within complex tissue...
Parkinson's disease (PD), the second most prevalent neurodegenerative disorder, is marked by dopaminergic neuron loss and α-synuclein aggregation. Alt...
Foodborne pathogens represent a significant threat to public health. The development of rapid and sensitive detection methods is critical for the effe...
Prostate cancer remains one of the most prevalent malignancies and a major cause of cancer‑related mortality among men worldwide. Despite widespread u...
Alternative splicing (AS) is one of the principal mechanisms of post‑transcriptional regulation that confers transcriptomic plasticity and proteomic d...