Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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EGeRepDR: An enhanced genetic-based representation learning for drug repurposing using multiple biomedical sources.

MOTIVATION: Drug repurposing (DR) is an imminent approach for identifying novel therapeutic indicati...

Oct 2023 37858852
Chromosome classification via deep learning and its application to patients with structural abnormalities of chromosomes.

BACKGROUND AND OBJECTIVE: Karyotyping is an important technique in cytogenetic practice for the earl...

Oct 2023 37985030
Deep-LASI: deep-learning assisted, single-molecule imaging analysis of multi-color DNA origami structures.

Single-molecule experiments have changed the way we explore the physical world, yet data analysis re...

Oct 2023 37848439
Deep learning based on susceptibility-weighted MR sequence for detecting cerebral microbleeds and classifying cerebral small vessel disease.

BACKGROUND: Cerebral microbleeds (CMBs) serve as neuroimaging biomarkers to assess risk of intracere...

Oct 2023 37848906
Improving Enhancer Identification with a Multi-Classifier Stacked Ensemble Model.

Enhancers are DNA regions that are responsible for controlling the expression of genes. Enhancers ar...

Oct 2023 37852600
KDeep: a new memory-efficient data extraction method for accurately predicting DNA/RNA transcription factor binding sites.

This paper addresses the crucial task of identifying DNA/RNA binding sites, which has implications i...

Oct 2023 37845681
[The Swecrit Biobank, associated clinical registries, and machine learning (artificial intelligence) improve critical care knowledge].

The unique Swecrit Biobank and its associated clinical registries for sepsis, ARDS, cardiac arrest, ...

Oct 2023 37846149
Predicting 3D RNA structure from the nucleotide sequence using Euclidean neural networks.

Fast and accurate 3D RNA structure prediction remains a major challenge in structural biology, mostl...

Oct 2023 37838833
c-Diadem: a constrained dual-input deep learning model to identify novel biomarkers in Alzheimer's disease.

BACKGROUND: Alzheimer's disease (AD) is an incurable, debilitating neurodegenerative disorder. Curre...

Oct 2023 37833700
Epigenetic target identification strategy based on multi-feature learning.

The identification of potential epigenetic targets for a known bioactive compound is essential and p...

Oct 2023 37827992
The impact of misclassification errors on the performance of biomarkers based on next-generation sequencing, a simulation study.

The development of next-generation sequencing (NGS) opens opportunities for new applications such as...

Oct 2023 37819021
One label is all you need: Interpretable AI-enhanced histopathology for oncology.

Artificial Intelligence (AI)-enhanced histopathology presents unprecedented opportunities to benefit...

Oct 2023 37832751
Enhanced detection of Listeria monocytogenes using tetraethylenepentamine-functionalized magnetic nanoparticles and LAMP-CRISPR/Cas12a-based biosensor.

BACKGROUND: Listeria monocytogenes is a pathogenic bacterium that can lead to severe illnesses, espe...

Oct 2023 38783743
disperseNN2: a neural network for estimating dispersal distance from georeferenced polymorphism data.

Spatial genetic variation is shaped in part by an organism's dispersal ability. We present a deep le...

Oct 2023 37817115
Inherently interpretable position-aware convolutional motif kernel networks for biological sequencing data.

Artificial neural networks show promising performance in detecting correlations within data that are...

Oct 2023 37821530
A Machine-Learning-Based Approach to Prediction of Biogeographic Ancestry within Europe.

Data obtained with the use of massive parallel sequencing (MPS) can be valuable in population geneti...

Oct 2023 37894775
Ultra-fast deep-learned CNS tumour classification during surgery.

Central nervous system tumours represent one of the most lethal cancer types, particularly among chi...

Oct 2023 37821699
Emerging applications of machine learning in genomic medicine and healthcare.

The integration of artificial intelligence technologies has propelled the progress of clinical and g...

Oct 2023 37815417
Reliable interpretability of biology-inspired deep neural networks.

Deep neural networks display impressive performance but suffer from limited interpretability. Biolog...

Oct 2023 37816807
Patient Graph Deep Learning to Predict Breast Cancer Molecular Subtype.

Breast cancer is a heterogeneous disease consisting of a diverse set of genomic mutations and clinic...

Oct 2023 37379184
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