Genetics

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Predicting RNA SHAPE scores with deep learning.

Secondary structure prediction approaches rely typically on models of equilibrium free energies that...

Beyond the limitation of targeted therapy: Improve the application of targeted drugs combining genomic data with machine learning.

Precision oncology involves effectively selecting drugs for cancer patients and planning an effectiv...

A machine learning model that classifies breast cancer pathologic complete response on MRI post-neoadjuvant chemotherapy.

BACKGROUND: For breast cancer patients undergoing neoadjuvant chemotherapy (NAC), pathologic complet...

Machine Learning and Multiparametric Brain MRI to Differentiate Hereditary Diffuse Leukodystrophy with Spheroids from Multiple Sclerosis.

BACKGROUND AND PURPOSE: Hereditary diffuse leukoencephalopathy with spheroids (HDLS) and multiple sc...

Artificial intelligence in gastroenterology: where are we heading?

Artificial intelligence (AI) is coming to medicine in a big wave. From making diagnosis in various m...

Predicting host taxonomic information from viral genomes: A comparison of feature representations.

The rise in metagenomics has led to an exponential growth in virus discovery. However, the majority ...

Identifying barley pan-genome sequence anchors using genetic mapping and machine learning.

We identified 1.844 million barley pan-genome sequence anchors from 12,306 genotypes using genetic m...

CHEER: HierarCHical taxonomic classification for viral mEtagEnomic data via deep leaRning.

The fast accumulation of viral metagenomic data has contributed significantly to new RNA virus disco...

LPI-CNNCP: Prediction of lncRNA-protein interactions by using convolutional neural network with the copy-padding trick.

Long noncoding RNAs (lncRNAs) play critical roles in many pathological and biological processes, suc...

Rosetta custom score functions accurately predict ΔΔG of mutations at protein-protein interfaces using machine learning.

Protein-protein interfaces play essential roles in a variety of biological processes and many therap...

Combining gene expression profiling and machine learning to diagnose B-cell non-Hodgkin lymphoma.

Non-Hodgkin B-cell lymphomas (B-NHLs) are a highly heterogeneous group of mature B-cell malignancies...

A biochemically-interpretable machine learning classifier for microbial GWAS.

Current machine learning classifiers have successfully been applied to whole-genome sequencing data ...

A novel graph attention adversarial network for predicting disease-related associations.

Identifying complex human diseases at molecular level is very helpful, especially in diseases diagno...

Drug Resistance Prediction Using Deep Learning Techniques on HIV-1 Sequence Data.

The fast replication rate and lack of repair mechanisms of human immunodeficiency virus (HIV) contri...

Jupyter notebook-based tools for building structured datasets from the Sequence Read Archive.

The Sequence Read Archive (SRA) is a large public repository that stores raw next-generation sequenc...

Putative cell type discovery from single-cell gene expression data.

We present the Single-Cell Clustering Assessment Framework, a method for the automated identificatio...

Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature.

The transcriptional activation and repression during NK cell ontology are poorly understood. Here, u...

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