Genetics

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DeepSV: accurate calling of genomic deletions from high-throughput sequencing data using deep convolutional neural network.

BACKGROUND: Calling genetic variations from sequence reads is an important problem in genomics. Ther...

Identification of aberrantly methylated‑differentially expressed genes and gene ontology in prostate cancer.

Prostate cancer (PCa) is the most frequent urological malignancy in men worldwide. DNA methylation h...

Hollow Alginate-Poly-L-Lysine-Alginate Microspheres Promoted an Epithelial-Mesenchymal Transition in Human Colon Adenocarcinoma Cells.

Today, there is an urgent need to develop a three-dimentional culture systems mimicking native con...

Effective machine-learning assembly for next-generation amplicon sequencing with very low coverage.

BACKGROUND: In short-read DNA sequencing experiments, the read coverage is a key parameter to succes...

Machine-learning based patient classification using Hepatitis B virus full-length genome quasispecies from Asian and European cohorts.

Chronic infection with Hepatitis B virus (HBV) is a major risk factor for the development of advance...

PharmVar GeneFocus: CYP2D6.

The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic hu...

The complete chloroplast genome of , lights into phylogenetic and taxonomic analyses.

a precious endangered species in China, it has a long history of growth and high ornamental and edi...

Discovery and annotation of novel microRNAs in the porcine genome by using a semi-supervised transductive learning approach.

Despite the broad variety of available microRNA (miRNA) prediction tools, their application to the d...

Identifying pseudoenzymes using functional annotation: pitfalls of common practice.

Pseudoenzymes are proteins that are evolutionary related to enzymes but lack relevant catalytic acti...

Global transcriptome analysis reveals relevant effects at environmental concentrations of cypermethrin in honey bees (Apis mellifera).

Cypermethrin is a frequently used insecticide in agriculture and households but its chronic and mole...

Filtering maxRatio results with machine learning models increases quantitative PCR accuracy over the fit point method.

With qPCR reaching thousands of reactions per run, assay validation needs automation. We applied sup...

Afann: bias adjustment for alignment-free sequence comparison based on sequencing data using neural network regression.

Alignment-free methods, more time and memory efficient than alignment-based methods, have been widel...

Machine learning approach to single nucleotide polymorphism-based asthma prediction.

Machine learning (ML) is poised as a transformational approach uniquely positioned to discover the h...

Machine Learning Enables High-Throughput Phenotyping for Analyses of the Genetic Architecture of Bulliform Cell Patterning in Maize.

Bulliform cells comprise specialized cell types that develop on the adaxial (upper) surface of grass...

TSLRF: Two-Stage Algorithm Based on Least Angle Regression and Random Forest in genome-wide association studies.

One of the most important tasks in genome-wide association analysis (GWAS) is the detection of singl...

The integrative knowledge base for miRNA-mRNA expression in colorectal cancer.

"miRNA colorectal cancer" (https://mirna-coadread.omics.si/) is a freely available web application f...

CDSeq: A novel complete deconvolution method for dissecting heterogeneous samples using gene expression data.

Quantifying cell-type proportions and their corresponding gene expression profiles in tissue samples...

NNTox: Gene Ontology-Based Protein Toxicity Prediction Using Neural Network.

With advancements in synthetic biology, the cost and the time needed for designing and synthesizing ...

RNA secondary structure prediction using an ensemble of two-dimensional deep neural networks and transfer learning.

The majority of our human genome transcribes into noncoding RNAs with unknown structures and functio...

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