Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Toward automatic prediction of EGFR mutation status in pulmonary adenocarcinoma with 3D deep learning.

To develop a deep learning system based on 3D convolutional neural networks (CNNs), and to automatic...

Recent methodology progress of deep learning for RNA-protein interaction prediction.

Interactions between RNAs and proteins play essential roles in many important biological processes. ...

Gene pathogenicity prediction of Mendelian diseases via the random forest algorithm.

The study of Mendelian diseases and the identification of their causative genes are of great signifi...

New Deep Learning Genomic-Based Prediction Model for Multiple Traits with Binary, Ordinal, and Continuous Phenotypes.

Multiple-trait experiments with mixed phenotypes (binary, ordinal and continuous) are not rare in an...

Association of genomic subtypes of lower-grade gliomas with shape features automatically extracted by a deep learning algorithm.

Recent analysis identified distinct genomic subtypes of lower-grade glioma tumors which are associat...

Statistical learning approaches in the genetic epidemiology of complex diseases.

In this paper, we give an overview of methodological issues related to the use of statistical learni...

Hemochromatosis in India: First Report of Whole Exome Sequencing With Review of the Literature.

BACKGROUND: Primary hemochromatosis is unusual in India. The homeostatic iron regulator (HFE) gene C...

MLSeq: Machine learning interface for RNA-sequencing data.

BACKGROUND AND OBJECTIVE: In the last decade, RNA-sequencing technology has become method-of-choice ...

Deep Learning/Artificial Intelligence and Blood-Based DNA Epigenomic Prediction of Cerebral Palsy.

The etiology of cerebral palsy (CP) is complex and remains inadequately understood. Early detection ...

Predicting miRNA-lncRNA interactions and recognizing their regulatory roles in stress response of plants.

It has been found that each non-coding RNA (ncRNA) can act not only through its target gene, but als...

Prediction of binding property of RNA-binding proteins using multi-sized filters and multi-modal deep convolutional neural network.

RNA-binding proteins (RBPs) are important in gene expression regulations by post-transcriptional con...

Cells in ExperimentaL Life Sciences (CELLS-2018): capturing the knowledge of normal and diseased cells with ontologies.

Cell cultures and cell lines are widely used in life science experiments. In conjunction with the 20...

Machine learning technology in the application of genome analysis: A systematic review.

Machine learning (ML) is a powerful technique to tackle many problems in data mining and predictive ...

Machine-learning based radiogenomics analysis of MRI features and metagenes in glioblastoma multiforme patients with different survival time.

BACKGROUND: This study aimed to examine multi-dimensional MRI features' predictability on survival o...

PGxO and PGxLOD: a reconciliation of pharmacogenomic knowledge of various provenances, enabling further comparison.

BACKGROUND: Pharmacogenomics (PGx) studies how genomic variations impact variations in drug response...

SPINDLE: End-to-end learning from EEG/EMG to extrapolate animal sleep scoring across experimental settings, labs and species.

Understanding sleep and its perturbation by environment, mutation, or medication remains a central p...

DNAPred: Accurate Identification of DNA-Binding Sites from Protein Sequence by Ensembled Hyperplane-Distance-Based Support Vector Machines.

Accurate identification of protein-DNA binding sites is significant for both understanding protein f...

A directed learning strategy integrating multiple omic data improves genomic prediction.

Genomic prediction (GP) aims to construct a statistical model for predicting phenotypes using genome...

Hybrid model for efficient prediction of poly(A) signals in human genomic DNA.

Polyadenylation signals (PAS) are found in most protein-coding and some non-coding genes in eukaryot...

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