Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 4600-4620 of 11,117 articles
Predicting the animal hosts of coronaviruses from compositional biases of spike protein and whole genome sequences through machine learning.

The COVID-19 pandemic has demonstrated the serious potential for novel zoonotic coronaviruses to eme...

Apr 2021 33878118
Iterative single-cell multi-omic integration using online learning.

Integrating large single-cell gene expression, chromatin accessibility and DNA methylation datasets ...

Apr 2021 33875866
An approach using ddRADseq and machine learning for understanding speciation in Antarctic Antarctophilinidae gastropods.

Sampling impediments and paucity of suitable material for molecular analyses have precluded the stud...

Apr 2021 33875688
A convolutional neural network for the prediction and forward design of ribozyme-based gene-control elements.

Ribozyme switches are a class of RNA-encoded genetic switch that support conditional regulation of g...

Apr 2021 33860764
Detecting protein and DNA/RNA structures in cryo-EM maps of intermediate resolution using deep learning.

An increasing number of density maps of macromolecular structures, including proteins and DNA/RNA co...

Apr 2021 33863902
CBCR: A Curriculum Based Strategy For Chromosome Reconstruction.

In this paper, we introduce a novel algorithm that aims to estimate chromosomes' structure from thei...

Apr 2021 33923653
Accurate cancer phenotype prediction with AKLIMATE, a stacked kernel learner integrating multimodal genomic data and pathway knowledge.

Advancements in sequencing have led to the proliferation of multi-omic profiles of human cells under...

Apr 2021 33861732
The Predictive Value of Monocytes in Immune Microenvironment and Prognosis of Glioma Patients Based on Machine Learning.

Gliomas are primary malignant brain tumors. Monocytes have been proved to actively participate in tu...

Apr 2021 33959130
Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning.

The optimization of therapeutic antibodies is time-intensive and resource-demanding, largely because...

Apr 2021 33859386
Novel application of automated machine learning with MALDI-TOF-MS for rapid high-throughput screening of COVID-19: a proof of concept.

The 2019 novel coronavirus infectious disease (COVID-19) pandemic caused by severe acute respiratory...

Apr 2021 33859233
Analysis of Tumor Microenvironment Characteristics in Bladder Cancer: Implications for Immune Checkpoint Inhibitor Therapy.

The tumor microenvironment (TME) plays a crucial role in cancer progression and recent evidence has ...

Apr 2021 33936117
Machine learning, transcriptome, and genotyping chip analyses provide insights into SNP markers identifying flower color in Platycodon grandiflorus.

Bellflower is an edible ornamental gardening plant in Asia. For predicting the flower color in bellf...

Apr 2021 33850210
Improving protein domain classification for third-generation sequencing reads using deep learning.

BACKGROUND: With the development of third-generation sequencing (TGS) technologies, people are able ...

Apr 2021 33836667
Artificial neural network model for predicting changes in ion channel conductance based on cardiac action potential shapes generated via simulation.

Many studies have revealed changes in specific protein channels due to physiological causes such as ...

Apr 2021 33837240
i6mA-VC: A Multi-Classifier Voting Method for the Computational Identification of DNA N6-methyladenine Sites.

DNA N6-methyladenine (6 mA), as an essential component of epigenetic modification, cannot be neglect...

Apr 2021 33834381
Interpretation of allele-specific chromatin accessibility using cell state-aware deep learning.

Genomic sequence variation within enhancers and promoters can have a significant impact on the cellu...

Apr 2021 33832990
Optimal Bayesian Transfer Learning for Count Data.

There is often a limited amount of omics data to design predictive models in biomedicine. Knowing th...

Apr 2021 31180899
A Hybrid Supervised Approach to Human Population Identification Using Genomics Data.

Single nucleotide polymorphisms (SNPs) are one type of genetic variations and each SNP represents a ...

Apr 2021 31150342
DeepDSC: A Deep Learning Method to Predict Drug Sensitivity of Cancer Cell Lines.

High-throughput screening technologies have provided a large amount of drug sensitivity data for a p...

Apr 2021 31150344
Distinguishing between recent balancing selection and incomplete sweep using deep neural networks.

Balancing selection is an important adaptive mechanism underpinning a wide range of phenotypes. Desp...

Apr 2021 33749134
Prediction of PCR amplification from primer and template sequences using recurrent neural network.

We have developed a novel method to predict the success of PCR amplification for a specific primer s...

Apr 2021 33820936
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