Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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A first perturbome of Pseudomonas aeruginosa: Identification of core genes related to multiple perturbations by a machine learning approach.

Tolerance to stress conditions is vital for organismal survival, including bacteria under specific e...

Mar 2021 33757842
Deep generative neural network for accurate drug response imputation.

Drug response differs substantially in cancer patients due to inter- and intra-tumor heterogeneity. ...

Mar 2021 33741950
iORI-ENST: identifying origin of replication sites based on elastic net and stacking learning.

DNA replication is not only the basis of biological inheritance but also the most fundamental proces...

Mar 2021 33730950
Integrated multi-omics analysis of ovarian cancer using variational autoencoders.

Cancer is a complex disease that deregulates cellular functions at various molecular levels (e.g., D...

Mar 2021 33737557
Machine Learning Prediction and Experimental Validation of Antigenic Drift in H3 Influenza A Viruses in Swine.

The antigenic diversity of influenza A viruses (IAV) circulating in swine challenges the development...

Mar 2021 33731472
PhotoModPlus: A web server for photosynthetic protein prediction from genome neighborhood features.

A new web server called PhotoModPlus is presented as a platform for predicting photosynthetic protei...

Mar 2021 33730083
Sparse deep neural networks on imaging genetics for schizophrenia case-control classification.

Deep learning methods hold strong promise for identifying biomarkers for clinical application. Howev...

Mar 2021 33724588
AptaNet as a deep learning approach for aptamer-protein interaction prediction.

Aptamers are short oligonucleotides (DNA/RNA) or peptide molecules that can selectively bind to thei...

Mar 2021 33727685
JSOM: Jointly-evolving self-organizing maps for alignment of biological datasets and identification of related clusters.

With the rapid advances of various single-cell technologies, an increasing number of single-cell dat...

Mar 2021 33724985
DeepTCR is a deep learning framework for revealing sequence concepts within T-cell repertoires.

Deep learning algorithms have been utilized to achieve enhanced performance in pattern-recognition t...

Mar 2021 33707415
A two-stream convolutional neural network for microRNA transcription start site feature integration and identification.

MicroRNAs (miRNAs) play important roles in post-transcriptional gene regulation and phenotype develo...

Mar 2021 33707582
DeepVISP: Deep Learning for Virus Site Integration Prediction and Motif Discovery.

Approximately 15% of human cancers are estimated to be attributed to viruses. Virus sequences can be...

Mar 2021 33977077
Deep learning-based enhancement of epigenomics data with AtacWorks.

ATAC-seq is a widely-applied assay used to measure genome-wide chromatin accessibility; however, its...

Mar 2021 33686069
Prioritizing non-coding regions based on human genomic constraint and sequence context with deep learning.

Elucidating functionality in non-coding regions is a key challenge in human genomics. It has been sh...

Mar 2021 33686085
Development of a neuron model based on DNAzyme regulation.

Neural networks based on DNA molecular circuits play an important role in molecular information proc...

Mar 2021 35423534
seqQscorer: automated quality control of next-generation sequencing data using machine learning.

Controlling quality of next-generation sequencing (NGS) data files is a necessary but complex task. ...

Mar 2021 33673854
Deep Matrix Factorization Improves Prediction of Human CircRNA-Disease Associations.

In recent years, more and more evidence indicates that circular RNAs (circRNAs) with covalently clos...

Mar 2021 32750925
Machine Learning Model for Computational Tracking and Forecasting the COVID-19 Dynamic Propagation.

A computational model with intelligent machine learning for analysis of epidemiological data, is pro...

Mar 2021 33449891
Discovering Collective Variables of Molecular Transitions via Genetic Algorithms and Neural Networks.

With the continual improvement of computing hardware and algorithms, simulations have become a power...

Mar 2021 33662202
Artificial intelligence prediction model for overall survival of clear cell renal cell carcinoma based on a 21-gene molecular prognostic score system.

We developed and validated a new prognostic model for predicting the overall survival in clear cell ...

Mar 2021 33686949
DeeReCT-APA: Prediction of Alternative Polyadenylation Site Usage Through Deep Learning.

Alternative polyadenylation (APA) is a crucial step in post-transcriptional regulation. Previous bio...

Mar 2021 33662629
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