Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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DNA is not an ontologically distinctive developmental cause.

In this article I critically evaluate the thesis that DNA is an ontologically distinctive developmen...

Dec 2019 31899119
The sweet detection of rolling circle amplification: Glucose-based electrochemical genosensor for the detection of viral nucleic acid.

Herein, an isothermal padlock probe-based assay for the simple and portable detection of pathogens c...

Dec 2019 31999596
Prediction of IDH and TERT promoter mutations in low-grade glioma from magnetic resonance images using a convolutional neural network.

Identification of genotypes is crucial for treatment of glioma. Here, we developed a method to predi...

Dec 2019 31889117
Using transfer learning from prior reference knowledge to improve the clustering of single-cell RNA-Seq data.

In many research areas scientists are interested in clustering objects within small datasets while m...

Dec 2019 31889137
Epigenetics Analysis and Integrated Analysis of Multiomics Data, Including Epigenetic Data, Using Artificial Intelligence in the Era of Precision Medicine.

To clarify the mechanisms of diseases, such as cancer, studies analyzing genetic mutations have been...

Dec 2019 31905969
iProDNA-CapsNet: identifying protein-DNA binding residues using capsule neural networks.

BACKGROUND: Since protein-DNA interactions are highly essential to diverse biological events, accura...

Dec 2019 31881828
Predicting RNA secondary structure via adaptive deep recurrent neural networks with energy-based filter.

BACKGROUND: RNA secondary structure prediction is an important issue in structural bioinformatics, a...

Dec 2019 31874602
JCDB: a comprehensive knowledge base for Jatropha curcas, an emerging model for woody energy plants.

BACKGROUND: Jatropha curcas is an oil-bearing plant, and has seeds with high oil content (~ 40%). Se...

Dec 2019 31874631
iEnhancer-ECNN: identifying enhancers and their strength using ensembles of convolutional neural networks.

BACKGROUND: Enhancers are non-coding DNA fragments which are crucial in gene regulation (e.g. transc...

Dec 2019 31874637
Towards Improving Skin Cancer Diagnosis by Integrating Microarray and RNA-Seq Datasets.

Many clinical studies have revealed the high biological similarities existing among different skin p...

Dec 2019 31871000
A tri-functional probe mediated exponential amplification strategy for highly sensitive detection of Dnmt1 and UDG activities at single-cell level.

Multiplex DNA methylation and glycosylation are ubiquitous in the human body to ensure the normal fu...

Dec 2019 32081181
High-Throughput Prediction of MHC Class I and II Neoantigens with MHCnuggets.

Computational prediction of binding between neoantigen peptides and major histocompatibility complex...

Dec 2019 31871119
Super-Soft and Super-Elastic DNA Robot with Magnetically Driven Navigational Locomotion for Cell Delivery in Confined Space.

Soft organisms such as earthworms can access confined, narrow spaces, inspiring scientists to fabric...

Dec 2019 31769147
Adipocyte Fatty Acid-Binding Protein 4 is Altered in Growth Discordant Dichorionic, but not in Monochorionic Twins.

CONTEXT: The fetal period has a critical and long-lasting impact on the regulation of metabolic proc...

Dec 2019 32258957
Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures.

OBJECTIVE: Type 2 diabetes (T2D) is a complex disease characterized by pancreatic islet dysfunction,...

Dec 2019 32029221
In vitro selection of DNA aptamers and their integration in a competitive voltammetric biosensor for azlocillin determination in waste water.

The uncontrolled usage of veterinary antibiotics has led to their widespread pollution in waterways ...

Dec 2019 32029106
Transcriptome analysis and identification of genes associated with chicken sperm storage duration.

The sperm storage tubules located in the mucosal folds of the uterovaginal junction (UVJ) are the pr...

Dec 2019 32036969
Characterization of the complete chloroplast genome of traditional Tibetan herb, Maxim. (Polygonaceae).

The complete chloroplast genome sequence of traditional Tibetan herb, Maxim. was analyzed. The comp...

Dec 2019 33366455
Characterization and phylogenetic analysis of the complete chloroplast genome of 'Forest Pansy'.

'Forest Pansy' is a tree species with high ornamental value, which complete chloroplast (cp) genome...

Dec 2019 33366464
Complete chloroplast genome of (Rosaceae), a wild flowering cherry endemic to the Himalayan region.

is a species of Prunus native to the Himalayan region. We determined the first complete chloroplast...

Dec 2019 33366467
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